Oral Pathology

• Gingivitis - Immune Cells: Neutrophils are the predominant immune cells present in the first stage of gingivitis.

• Acute Necrotizing Ulcerative Gingivitis (ANUG): Involved papillae show punched out, crater-like necrotic areas covered by grayish pseudomembrane.

• Drug-Induced Gingival Enlargement: Never seen in edentulous areas, as there is no plaque in these areas for the drug to interact with.

• Papillon-Lefèvre Syndrome:

  • Cause: Mutation of the cathepsin C gene located on chromosome 11q14.

  • Result: Impaired chemotaxis and phagocytosis, leading to severe periodontitis and palmar/plantar hyperkeratosis.