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FAST REVISION
General Medicine
⚛️ Hodgkin’s Disease
| Feature | Insight |
|---|---|
| Distinct subtype | Lymphocyte predominant |
| Hallmark cells | Reed-Sternberg & Lacunar cells |
| Markers | CD15 & CD30 |
| Best prognosis | Lymphocyte predominant |
| Treatment | Stage IA → Radiotherapy; Advanced → ABVD regimen |
- Most common subtype: Nodular sclerosis
- Common in India: Mixed cellularity
🧬 Non-Hodgkin’s Lymphoma
- Classification: REAL
- Burkitt lymphoma: Most malignant; t(8;14) & t(2;8) translocations
- EBV association noted
- Angiocentric lymphoma: Non – B-cell