NEET MDS Shorts
688612
General PathologyNiemann-Pick disease is characterized by a deficiency of sphingomyelinase, not aryl sulfatase, and involves chromosome 11 in its genetic basis.
997849
General PathologySickle cell mutation is a point mutation, specifically a single nucleotide substitution in the ?-globin gene.
203536
General PathologyOsteopetrosis is characterized by thick and brittle bones due to increased osteoclast activity, which is impaired, leading to abnormal bone remodeling.
795173
General PathologyThromboxane A2, produced in the lipooxygenase pathway, promotes platelet aggregation and vasoconstriction, playing a key role in hemostasis.
652256
General PathologyDiverticulitis is characterized by left lower quadrant pain, fever, and leukocytosis, especially in elderly patients.
942585
General PathologyReticulocytosis is commonly seen in hemolytic anemia, where there is increased production of red blood cells in response to anemia.
896892
General PathologyConjunctivitis is often associated with Sjögren's syndrome, which can cause oral mucosal swelling and xerostomia.
738961
General PathologyHeterozygous sickle cell anemia provides protection against malaria due to the altered red blood cell environment that is less hospitable to the malaria parasite.