NEET MDS Synopsis
Blood Supply to the Head and Neck
AnatomyBlood Supply to the Head and Neck
Most arteries in the anterior cervical triangle arise from the common carotid artery or one of the branches of the external carotid artery.
Most veins in the anterior cervical triangle are tributaries of the large internal jugular vein.
The Common Carotid Arteries
The right common carotid artery begins at the bifurcation of the brachiocephalic trunk, posterior to the right sternoclavicular joint.
The left common carotid artery begins arises from the arch of the aorta and ascends into the neck, posterior to the left sternoclavicular joint.
Each common carotid artery ascends into the neck within the carotid sheath to the level of the superior border of the thyroid cartilage.
Here it terminates by dividing into the internal and external carotid arteries.
The Internal Carotid Artery
This is the direct continuation of the common carotid artery and it has no branches in the neck.
It supplies structures inside the skull.
The internal carotid arteries are two of the four main arteries that supply blood to the brain.
Each artery arises from the common carotid at the level of the superior border of the thyroid cartilage.
It then passes superiorly, almost in a vertical plane, to enter the carotid canal in the petrous part of the temporal bone.
A plexus of sympathetic fibres accompany it.
During its course through the neck, the internal carotid artery lies on the longus capitis muscle and the sympathetic trunk.
The vagus nerve (CN X) lies posterolateral to it.
The internal carotid artery enters the middle cranial fossa beside the dorsum sellae of the sphenoid bone.
Within the cranial cavity, the internal carotid artery and its branches supply the hypophysis cerebri (pituitary gland), the orbit, and most of the supratentorial part of the brain.
The External Carotid Arteries
This vessel begins at the bifurcation of the common carotid, at the level of the superior border of the thyroid cartilage.
It supplies structures external to the skull.
The external carotid artery runs posterosuperiorly to the region between the neck of the mandible and the lobule of the auricle.
It terminates by dividing into two branches, the maxillary and superficial temporal arteries.
The stems of most of the six branches of the external carotid artery are in the carotid triangle.
The Superior Thyroid Artery
This is the most inferior of the 3 anterior branches of the external carotid.
It arises close to the origin of the vessel, just inferior to the greater horn of the hyoid.
The superior thyroid artery runs anteroinferiorly, deep to the infrahyoid muscles and gives off the superior laryngeal artery. This artery pierces the thyrohyoid membrane in company with the internal laryngeal nerve and supplies the larynx.
The Lingual Artery
This arises from the external carotid artery as it lies on the middle constrictor muscle of the pharynx.
It arches superoanteriorly, about 5 mm superior to the tip of the greater horn of the hyoid bone, and then passes deep to the hypoglossal nerve, the stylohyoid muscle, and the posterior belly of digastric muscle.
It disappears deep to the hyoglossus muscle.
At the anterior border of this muscle, it turns superiorly and ends by becoming the deep lingual artery.
The Facial Artery
This arises from the carotid artery either, in common with the lingual artery, or immediately superior to it.
In the neck the facial artery gives off its important tonsillar branch and branches to the palate and submandibular gland.
The facial artery then passes superiorly under the cover of the digastric and stylohyoid muscles and the angle of the mandible.
It loops anteriorly and enters a deep groove in the submandibular gland.
The facial artery hooks around the inferior border of the mandible and enters the face. Here the pulsation of this artery can be felt (anterior to the masseter muscle).
The Ascending Pharyngeal Artery
This is the 1st or 2nd branch of the external carotid artery.
This small vessel ascends on the pharynx, deep to the internal carotid artery.
It sends branches to the pharynx, prevertebral muscles, middle ear and meninges.
The Occipital Artery
This arises from the posterior surface of the external carotid near the level of the facial artery.
It passes posteriorly along the inferior border of the posterior belly of digastric.
It ends in the posterior part of the scalp.
During its course, it is superficial to the internal carotid artery and three cranial nerves (CN IX, CN X and CN XI).
The Posterior Auricular Artery
This is a small posterior branch of the external carotid artery.
It arises from it at the superior border of the posterior belly of the digastric muscle.
It ascends posteriorly to the external acoustic meatus and supplies adjacent muscles, the parotid gland, the facial nerve, structures in the temporal bone, the auricle, and the scalp.
The Internal Jugular Vein
This is usually the largest vein in the neck.
The internal jugular vein drains blood from the brain and superficial parts of the face and neck.
Its course corresponds to a line drawn from a point immediately inferior to the external acoustic meatus to the medial end of the clavicle.
This large vein commences at the jugular foramen in the posterior cranial fossa, as the direct continuation of the sigmoid sinus.
The dilation at its origin is called the superior bulb of the internal jugular vein.
From here it runs inferiorly through the neck in the carotid sheath.
The internal jugular vein leaves the anterior triangle of the neck by passing deep to the SCM muscle.
Posterior to the sternal end of the clavicle, it unites with the subclavian vein to form the brachiocephalic vein.
Near its termination is the inferior bulb of the jugular vein contains a bicuspid valve similar to that of the subclavian vein.
The deep cervical lymph nodes lie along the course of the internal jugular vein, mostly lateral and posterior.
Tributaries of the Internal Jugular Vein
This large vein is joined at its origin by the: inferior petrosal sinus, the facial, lingual, pharyngeal, superior and middle thyroid veins, and often the occipital vein.
Colla Cote
PedodonticsColla Cote
Colla Cote is a biocompatible, soft, white, and pliable sponge derived from
bovine collagen. It is designed for various dental and surgical applications,
particularly in endodontics. Here are its key features and benefits:
Biocompatibility: Colla Cote is made from natural bovine
collagen, ensuring compatibility with human tissue and minimizing the risk
of adverse reactions.
Moisture Tolerance: This absorbable collagen barrier can
be effectively applied to moist or bleeding canals, making it suitable for
use in challenging clinical situations.
Extravasation Prevention: Colla Cote is specifically
designed to prevent or reduce the extravasation of root canal filling
materials during primary molar pulpectomies, enhancing the success of the
procedure.
Versatile Applications: Beyond endodontic therapy, Colla
Cote serves as a scaffold for bone growth, making it useful in various
surgical contexts, including wound management.
Absorbable Barrier: As an absorbable material, Colla
Cote gradually integrates into the body, eliminating the need for removal
and promoting natural healing processes.
Dermatomes of the lower limb
Anatomy
Dermatome
Area supplied
L1
Inguinal area (over inguinal canal).
L2
Anterior and Lateral part of Upper 2/3rdof thigh.
L.3
Anterior, Lateral & Medial part of Lower 1I3'd of thigh and knee.
L4
Medial side of leg.
L5
Lateral side of leg, Medial half of dorsum of foot, first web space.
SI
Posterior surface of ankle, and lateral half of dorsum of foot.
S2
Posterior of thigh and leg.
S3
Gluteal area around perianal region, Groin.
S4
Perianal skin &Groin.
Glycogenolysis
Biochemistry
Glycogenolysis
Breakdown of glycogen to glucose is called glycogenolysis. The Breakdown of glycogen takes place in liver and muscle. In Liver , the end product of glycodgen breakdown is glucose where as in muscles the end product is Lactic acid Under the combined action of Phosphorylase (breaks only –α-(1,4) linkage )and Debranching enzymes (breaks only α-(1,6) linkage )glycogen is broken down to glucose.
Distraction Techniques
PedodonticsDistraction Techniques in Pediatric Dentistry
Distraction is a valuable technique used in pediatric dentistry to help
manage children's anxiety and discomfort during dental procedures. By diverting
the child's attention away from the procedure, dental professionals can create a
more positive experience and reduce the perception of pain or discomfort.
Purpose of Distraction
Divert Attention: The primary goal of distraction is to
shift the child's focus away from the dental procedure, which may be
perceived as unpleasant or frightening.
Reduce Anxiety: Distraction can help alleviate anxiety
and fear associated with dental visits, making it easier for children to
cooperate during treatment.
Enhance Comfort: Providing a break or a moment of
distraction during stressful procedures can enhance the overall comfort of
the child.
Techniques for Distraction
Storytelling:
Engaging the child in a story can capture their attention and
transport them mentally away from the dental environment.
Stories can be tailored to the child's interests, making them more
effective.
Counting Teeth:
Counting the number of teeth loudly can serve as a fun and
interactive way to keep the child engaged.
This technique can also help familiarize the child with the dental
procedure.
Repetitive Statements of Encouragement:
Providing continuous verbal encouragement can help reassure the
child and keep them focused on positive outcomes.
Phrases like "You're doing great!" or "Just a little longer!" can be
effective.
Favorite Jokes or Movies:
Asking the child to recall a favorite joke or movie can create a
light-hearted atmosphere and distract them from the procedure.
This technique can also foster a sense of connection between the
dentist and the child.
Audio-Visual Aids:
Utilizing videos, cartoons, or music can provide a visual and
auditory distraction that captures the child's attention.
Headphones with calming music or engaging videos can be particularly
effective during procedures like local anesthetic administration.
Application in Dental Procedures
Local Anesthetic Administration: Distraction techniques
can be especially useful during the administration of local anesthetics,
which may cause discomfort. Engaging the child in conversation or using
visual aids can help minimize their focus on the injection.
Haemolytic anaemia
General Pathology
Haemolytic anaemia
Anemia due to increased red cell destruction (shortened life span)
Causes:
A. Corpuscular defects:
1.Membrane defects:
- Spherocytosis.
- Elliptocytosis.
2. Haemoglobinopathies:
- Sickle cell anaemia.
- Thalassaemia
- Hb-C, HBD, HbE.
3. Enzyme defects .deficiency of:
- GIucose -6 phosphate dehydrogenase (G6-PD)
- Pyruvate kinase
4. Paroxysmal nocturnal haemoglobinuria.
B. Extracorpusular mechanisms
1. Immune based:
- Autoimmune haemolytic anaemia.
- Haemolytic disease of new born.
- Incompatible transfusion.
- Drug induced haemolysis
2. Mechanical haemolytic anaemia.
3. Miscellaneous due to :
- Drugs and chemicals.
- Infections.
- Burns.
features of haemolytic anaemia
- Evidence of increased Hb breakdown:
-> Unconjugated hyperbilirubinaemia.
-> Decreased plasma haptoglobin.
-> Increased urobilinogen and stercobilinogen.
-> Haemoglobinaemia, haemoglobinuria and haemosiderinuria if Intravascular haemolysis occurs.
- Evidence or compensatory erythroid hyperplasia:
-> Reticulocytosis and nucleated RBC in peripheral smear.
-> Polychromasia and macrocytes
-> Marrow erythroid hyperplasia
-> Skull and other bone changes.
- Evidences of damage to RBC:
-> Spherocytes and increased osmotic fragility
-> Shortened life span.
-> Fragmented RBC.
-> Heinz bodies.
Keratinized Gingiva and Attached Gingiva
PeriodontologyKeratinized Gingiva and Attached Gingiva
The gingiva is an essential component of the periodontal tissues, providing
support and protection for the teeth. Understanding the characteristics of
keratinized gingiva, particularly attached gingiva, is crucial for assessing
periodontal health.
Keratinized Gingiva
Definition:
Keratinized gingiva refers to the gingival tissue that is covered by
a layer of keratinized epithelium, providing a protective barrier
against mechanical and microbial insults.
Areas of Keratinized Gingiva:
Attached Gingiva:
Extends from the gingival groove to the mucogingival junction.
Marginal Gingiva:
The free gingival margin that surrounds the teeth.
Hard Palate:
The roof of the mouth, which is also covered by keratinized
tissue.
Attached Gingiva
Location:
The attached gingiva is the portion of the gingiva that is firmly
bound to the underlying alveolar bone.
Width of Attached Gingiva:
The width of attached gingiva varies based on location and can
increase with age and in cases of supraerupted teeth.
Measurements:
Greatest Width:
Found in the incisor region:
Maxilla: 3.5 mm - 4.5 mm
Mandible: 3.3 mm - 3.9 mm
Narrowest Width:
Found in the posterior region:
Maxillary First Premolar: 1.9 mm
Mandibular First Premolar: 1.8 mm
Clinical Significance
Importance of Attached Gingiva:
The width of attached gingiva is important for periodontal health,
as it provides a buffer zone against mechanical forces and helps
maintain the integrity of the periodontal attachment.
Insufficient attached gingiva may lead to increased susceptibility
to periodontal disease and gingival recession.
Assessment:
Regular assessment of the width of attached gingiva is essential
during periodontal examinations to identify potential areas of concern
and to plan appropriate treatment strategies.
BETA-LACTAM ANTIBIOTICS
Pharmacology
Carbapenems: Broadest spectrum of beta-lactam antibiotics.
imipenem with cilastatin
meropenem
ertapenem
Monobactams: Unlike other beta-lactams, there is no fused ring attached to beta-lactam nucleus. Thus, there is less probability of cross-sensitivity reactions.
aztreonam
Beta-lactamase Inhibitors No antimicrobial activity. Their sole purpose is to prevent the inactivation of beta-lactam antibiotics by beta-lactamases, and as such, they are co-administered with beta-lactam antibiotics.
clavulanic acid
tazobactam
sulbactam