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NEET MDS Synopsis

The developing tooth bud
Dental Anatomy

Tooth development is commonly divided into the following stages: the bud stage, the cap, the bell, and finally maturation. The staging of tooth development is an attempt to categorize changes that take place along a continuum; frequently it is difficult to decide what stage should be assigned to a particular developing tooth. This determination is further complicated by the varying appearance of different histological sections of the same developing tooth, which can appear to be different stages.

Bud stage

The bud stage is characterized by the appearance of a tooth bud without a clear arrangement of cells. The stage technically begins once epithelial cells proliferate into the ectomesenchyme of the jaw. The tooth bud itself is the group of cells at the end of the dental lamina.

Onlay Preparation
Conservative Dentistry

Onlay Preparation
Onlay preparations are a type of indirect restoration used to restore teeth
that have significant loss of structure but still retain enough healthy tooth
structure to support a restoration. Onlays are designed to cover one or more
cusps of a tooth and are often used when a full crown is not necessary.

1. Definition of Onlay
A. Onlay

An onlay is a restoration that is
fabricated using an indirect procedure, covering one or more cusps of a
tooth. It is designed to restore the tooth's function and aesthetics while
preserving as much healthy tooth structure as possible.


2. Indications for Onlay Preparation

Extensive Caries: When a tooth has significant decay
that cannot be effectively treated with a filling but does not require a
full crown.
Fractured Teeth: For teeth that have fractured cusps or
significant structural loss.
Strengthening: To reinforce a tooth that has been
weakened by previous restorations or caries.


3. Onlay Preparation Procedure
A. Initial Assessment

Clinical Examination: Assess the extent of caries or
damage to determine if an onlay is appropriate.
Radiographic Evaluation: Use X-rays to evaluate the
tooth structure and surrounding tissues.

B. Tooth Preparation


Burs Used:

Commonly used burs include No. 169 L for initial cavity preparation
and No. 271 for refining the preparation.



Cavity Preparation:

Occlusal Entry: The initial occlusal entry should
be approximately 1.5 mm deep.
Divergence of Walls: All cavity walls should
diverge occlusally by 2-5 degrees:
2 degrees: For short vertical walls.
5 degrees: For long vertical walls.





Proximal Box Preparation:

The proximal box margins should clear adjacent teeth by 0.2-0.5 mm,
with 0.5 ± 0.2 mm being ideal.



C. Bevels and Flares


Facial and Lingual Flares:

Primary and secondary flares should be created on the facial and
lingual proximal walls to form the walls in two planes.
The secondary flare widens the proximal box, allowing for better
access and cleaning.



Gingival Bevels:

Should be 0.5-1 mm wide and blend with the secondary flare,
resulting in a marginal metal angle of 30 degrees.



Occlusal Bevels:

Present on the cavosurface margins of the cavity on the occlusal
surface, approximately 1/4th the depth of the respective wall, resulting
in a marginal metal angle of 40 degrees.




4. Dimensions for Onlay Preparation
A. Depth of Preparation

Occlusal Depth: Approximately 1.5 mm to ensure adequate
thickness of the restorative material.
Proximal Box Depth: Should be sufficient to accommodate
the onlay while maintaining the integrity of the tooth structure.

B. Marginal Angles

Facial and Lingual Margins: Should be prepared with a
30-degree angle for burnishability and strength.
Enamel Margins: Ideally, the enamel margins should be
blunted to a 140-degree angle to enhance strength.

C. Cusp Reduction

Cusp Coverage: Cusp reduction is indicated when more
than 1/2 of a cusp is involved, and mandatory when 2/3 or more is involved.
Uniform Metal Thickness: The reduction must provide for
a uniform metal thickness of approximately 1.5 mm over the reduced cusps.
Facial Cusp Reduction: For maxillary premolars and
first molars, the reduction of the facial cusp should be 0.75-1 mm for
esthetic reasons.

D. Reverse Bevel

Definition: A bevel on the margins of the reduced cusp,
extending beyond any occlusal contact with opposing teeth, resulting in a
marginal metal angle of 30 degrees.


5. Considerations for Onlay Preparation

Retention and Resistance: The preparation should be
designed to maximize retention and resistance form, which may include the
use of proximal retentive grooves and collar features.
Aesthetic Considerations: The preparation should
account for the esthetic requirements, especially in anterior teeth or
visible areas.
Material Selection: The choice of material (e.g., gold,
porcelain, composite) will influence the preparation design and dimensions.

Extraction Patterns for Presurgical Orthodontics
Oral and Maxillofacial Surgery

Extraction Patterns for Presurgical Orthodontics
In orthodontics, the extraction pattern chosen can significantly influence
treatment outcomes, especially in presurgical orthodontics. The extraction
decisions differ based on the type of skeletal malocclusion, specifically Class
II and Class III malocclusions. Here’s an overview of
the extraction patterns for each type:
Skeletal Class II Malocclusion

General Approach:
In skeletal Class II malocclusion, the goal is to prepare the dental
arches for surgical correction, typically involving mandibular
advancement.


Extraction Recommendations:
No Maxillary Tooth Extraction: Avoid extracting
maxillary teeth, particularly the upper first premolars or any maxillary
teeth, to prevent over-retraction of the maxillary anterior teeth.
Over-retraction can compromise the planned mandibular advancement.
Lower First Premolar Extraction: Extraction of the
lower first premolars is recommended. This helps:
Level the arch.
Correct the proclination of the lower anterior teeth, allowing
for better alignment and preparation for surgery.





Skeletal Class III Malocclusion


General Approach:

In skeletal Class III malocclusion, the extraction pattern is
reversed to facilitate the surgical correction, often involving
maxillary advancement or mandibular setback.



Extraction Recommendations:

Upper First Premolar Extraction: Extracting the
upper first premolars is done to:
Correct the proclination of the upper anterior teeth, which is
essential for achieving proper alignment and aesthetics.


Lower Second Premolar Extraction: If additional
space is needed in the lower arch, the extraction of lower second
premolars is recommended. This helps:
Prevent over-retraction of the lower anterior teeth, maintaining
their position while allowing for necessary adjustments in the arch.





Functions of the nervous system
Physiology

Functions of the nervous system:

1) Integration of body processes

2) Control of voluntary effectors (skeletal muscles), and mediation of voluntary reflexes.

3) Control of involuntary effectors (  smooth muscle, cardiac muscle, glands) and mediation of autonomic reflexes (heart rate, blood pressure, glandular secretion, etc.)

4) Response to stimuli

5) Responsible for conscious thought and perception, emotions, personality, the mind.

Hormones of the Pituitary -The Posterior Lobe
Physiology

The Posterior Lobe

The posterior lobe of the pituitary releases two hormones, both synthesized in the hypothalamus, into the circulation.


Antidiuretic Hormone (ADH).
ADH is a peptide of 9 amino acids. It is also known as arginine vasopressin. ADH acts on the collecting ducts of the kidney to facilitate the reabsorption of water into the blood.

A deficiency of ADH

leads to excessive loss of urine, a condition known as diabetes  nsipidus.




Oxytocin
Oxytocin is a peptide of 9 amino acids. Its principal actions are:

stimulating contractions of the uterus at the time of birth
stimulating release of milk when the baby begins to suckle



Intrinsic pigmentation of teeth

Pedodontics

Erythroblastosis fetalis
Blue-green colour of primary teeth only. It is due to excessive haemolysis of
RBC. The Staining occurs due to diffusion of bilirubin and biliverdin into the
dentin

Porphyria
Purplish brown pigmentation. to light and blisters on The other features hands
and face e Hypersensitivity are are red red coloured urine, urine,

Cystic fibrosis
(Yellowish gray to dark brown. It is due to tetracycline, which is the drug of
choice in this disease

Tetracycline
Yellow or yellow-brown pigmentation in dentin and to a lesser extent in enamel
that are calcifying during the time the drug is administered. The teeth
fluoresce yellow under UV light 

Levofloxacin
Pharmacology

Levofloxacin

Levofloxacin is effective against a number of gram-positive and gram-negative bacteria. Because of its broad spectrum of action, levofloxacin is frequently prescribed in hospitals for pulmonary infections


Glycogen Storage Diseases

Biochemistry


Glycogen Storage Diseases are genetic enzyme deficiencies associated with excessive glycogen accumulation within cells.


When an enzyme defect affects mainly glycogen storage in liver, a common symptom is hypoglycemia (low blood glucose), relating to impaired mobilization of glucose for release to the blood during fasting.
When the defect is in muscle tissue, weakness and difficulty with exercise result from inability to increase glucose entry into Glycolysis during exercise.


Various type of Glycogen storage disease are





Type


Name


Enzyme Deficient




I


Von Geirke’s Disease


Glucose -6-phosphate




II


Pompe’s Disease


(1, 4)glucosidase




III


Cori’s Disease


Debranching Enzymes




IV


Andersen’s Disease


Branching Enzymes




V


McArdle’s Disease


Muscles Glycogen Phosphorylase





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