NEET MDS Shorts
866271
AnatomyThe largest resting membrane potential is observed in skeletal muscle.
Resting membrane potential (RMP) is the electrical potential difference across
the membrane of a cell when it is not undergoing an action potential or a
similar excitation. It is crucial for the functioning of excitable cells, such
as neurons and muscle cells, as it is the basis for the transmission of
electrical signals. The RMP is primarily determined by the concentration
gradients of ions across the cell membrane and the permeability of the membrane
to those ions.
In skeletal muscle cells, the resting membrane potential is typically around -90
millivolts (mV). This relatively high negative value is due to the higher
concentration of potassium ions (K+) inside the cell compared to the outside,
and the lower concentration of sodium ions (Na+) inside the cell compared to the
outside. The cell membrane is more permeable to K+ than to Na+ at rest, which
allows K+ to leak out through potassium channels and sets up the resting
membrane potential.
Smooth muscle cells, on the other hand, have a resting membrane potential that
is generally less negative than that of skeletal muscle cells. The typical RMP
in smooth muscle cells ranges from -40 to -70 mV, which is closer to the
threshold for depolarization and makes these cells more responsive to stimuli
that could cause contraction. The difference in RMP between smooth and skeletal
muscle is due to variations in ion channel expression and the activity of ion
pumps, which control the ionic composition of the intracellular and
extracellular environments.
To summarize:
1. Skeletal muscle cells have a resting membrane potential of approximately -90
mV.
2. Smooth muscle cells have a resting membrane potential that is generally more
positive than skeletal muscle cells, typically ranging from -40 to -70 mV.
564048
AnatomyFacial Artery:
1: True, it has cervical and facial portions.
2: True, it arises from the external carotid artery above the lingual artery.
3: True, it crosses the mandible at the anterior edge of the masseter muscle.
4: False, the cervical portion lies beneath the platysma,
but the facial portion does not exactly lie "superficial in the carotid
triangle"; rather, the facial artery travels more superficially than the
cervical part in its course.
632729
AnatomyThe artery chiefly responsible for blood supply to the mandible is inferior alveolar artery
854756
AnatomyThe medial pterygoid muscle is attached to the medial surface of lateral pterygoid plate
104500
AnatomyThese form specialized fibres of the heart and are supposed to be terminal filaments of bundle of His. They are placed beneath the endocardium and intervene between it and the myocardium.
213003
AnatomyIt attaches superiorly at the medial border of the mandible and inferiorly at the body of the hyoid
604410
AnatomyThe nerve to masseter passes through the mandibular notch to enter the muscle on its medial surface
The nerve to the masseter muscle is the masseteric nerve, which is a branch
of the mandibular nerve (CN V3), the largest division of the trigeminal nerve
(cranial nerve V). The masseter muscle is one of the muscles of mastication that
lifts the lower jaw, contributing to the action of biting and chewing.
The masseteric nerve originates from the anterior division of the mandibular
nerve and typically passes:
1. Deep to the medial pterygoid muscle: The medial pterygoid muscle is located
in the infratemporal fossa, which is the space deep to the zygomatic arch and
medial to the temporomandibular joint (TMJ). The masseteric nerve runs in a deep
position relative to the medial pterygoid muscle as it travels towards the
masseter muscle. This muscle is involved in the side-to-side movement of the
jaw, known as lateral excursion.
2. Posterior to the temporomandibular joint: The TMJ is the articulation between
the mandible and the temporal bone of the skull. It is a synovial joint that
allows for the hinge movement of the jaw, such as opening and closing the mouth.
The masseteric nerve passes behind the TMJ to reach the masseter muscle. This
nerve does not actually cross the joint itself but runs in a position posterior
to it.
3. Superior to the zygomatic arch: The zygomatic arch is the bony structure that
extends from the zygomatic process of the temporal bone to the zygomatic bone of
the skull. It forms the prominence of the cheek. The masseteric nerve runs
superior to the zygomatic arch to reach the masseter muscle. The arch serves as
a landmark for the nerve's course, and the nerve typically does not pass through
the arch itself.
4. Through the mandibular notch: This statement is not entirely correct. The
masseteric nerve does not pass through the mandibular notch, which is a
depression on the medial surface of the ramus of the mandible, but rather it
passes above (superior to) the notch. The mandibular notch is the location where
the masseteric nerve and the other branches of the mandibular nerve leave the
infratemporal fossa and enter the submandibular space to innervate the muscles
of mastication, including the masseter. The nerve then runs along the lateral
surface of the lateral pterygoid plate and enters the deep surface of the
masseter muscle.
In summary, the masseteric nerve passes deep to the medial pterygoid muscle,
posterior to the TMJ, and superior to the zygomatic arch. It does not pass
through the mandibular notch; instead, it runs superior to it before reaching
the masseter muscle. The anatomical pathway of this nerve allows it to
effectively innervate the masseter muscle, which is crucial for the function of
the muscle in mastication.
908559
AnatomyThe spleen follows the long axes of ribs 9 to 11 and lies mostly posterior to the stomach, above the colon, and partly anterior to the kidney. It is attached to the stomach by a broad mesenterial band, the gastrosplemic ligament. Therefore, it is the most likely organ of the group to be pierced by a sharp object penetrating just above rib 10 at the posterior axillary line. Note that the pleural cavity, and possibly the lower part of the inferior lobe of the lung, would be pierced before the spleen. The ascending colon (choice 1) is on the wrong side (the right) to be penetrated by a sharp instrument piercing the left side.
Most of the duodenum (choice 2) is positioned too far to the right to be affected by this injury.
Even the third part of the duodenum, which runs from right to left, would still be out of harm's way. In addition, the duodenum lies at about levels L1 to L3, placing it too low to be injured in this case.
The superior pole of the left kidney (choice 3) is bordered by the lower part of the spleen. However, it is crossed by rib 12 and usually does not extend above rib 11. It would probably be too low and medial to be injured in this case because this penetration is at the posterior axillary line.