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NEETMDS- Pharmacology short notes

NEET MDS Shorts

192104
Pharmacology

In humans, isosorbide mononitrate is not subject to first pass metabolism in the liver.

This reduces the intra- and interindividual variations in plasma evels and leads to predictable and reproducible clinical effects.

930075
Pharmacology

Beta-1 selective blockers

These include atenolol and metoprolol (as well as betaxolol, bevantolol, and perhaps esmolol). 

Non-selective beta blockers

propranolol 

429048
Pharmacology

Is a TCA- block neuronal uptake of noradrenaline and serotonin. and thus increase its conc. at synapse. they also block muscarinic, histaminergic, and adrenergic receptor

879475
Pharmacology

Dopamine as a first line of drug in patients with shock 

Dopamine in low doses can dilate renal vasculature therefore maintaining glomerular filtration.

Activates adenylate cyclase - cAMP – relaxation of vascular smooth muscle

303778
Pharmacology

Permanent auditory nerve deafness is frequently associated with use of streptomycin

616313
Pharmacology

Adrenaline is contraindicated in hypertensive, hyperthyroid and angina patient.

Hypersensitivity to drug is absolute contraindication to any drug.

330141
Pharmacology

Phenytoin inhibits insulin secretion and causes hyperglycemia.

634117
Pharmacology

Liposomal delivery systems decrease the amount of free drug in the blood Infected cells interact with the liposomes, resulting in the release of amphotericin B at the site of action.

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