What is the primary mechanism of action of antihistamines in the management of anaphylaxis?
1) Blocking the release of mediators from mast cells
2) Directly counteracting the effects of histamine on H1 receptors
3) Acting on beta-2 adrenergic receptors to dilate bronchioles
4) Inhibiting the production of leukotrienes and prostaglandins
📝 Explanation:
Antihistamines, particularly H1 blockers, are used to counteract the vasodilatory and bronchoconstrictive effects of histamine in anaphylaxis.