NEETMDS.com -Pharmacology- demo

1 Pharmacology

Permanent auditory nerve deafness is frequently associated with use of 1. tetracycline 2. penicillin 3. bacitracin 4. streptomycin

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Option 4

Permanent auditory nerve deafness is frequently associated with use of streptomycin

2 Pharmacology

Which of the following is a Beta-1 selective blocker ?

1) propranolol
2) nadolol
3) pindolol
4) betaxolol

Option 1

Option 2

Option 3

Option 4

Beta-1 selective blockers

These include atenolol and metoprolol (as well as betaxolol, bevantolol, and perhaps esmolol).

Non-selective beta blockers

propranolol

3 Pharmacology

In Dicumarol poisoning which Vit K is used

1) Menadione
2) Menaqunone
3) Phytonadione
4) None of the above

Option 1

Option 2

Option 3

To reverse the effect of overdose of oral anticoagulants:
Phytonadione (K1) is the preparation of choice, because it acts most rapidly, dose depends on the severity of upoprothrombinemia & bleeding.

Option 4

4 Pharmacology

The neuromuscular blocker that does not need reversal of action by neostigmine at the end of the operation is :

1) d–Tubocurarine
2) Doxacurium
3) Pipecuronium
4) Mivacurium

Option 1

Option 2

Option 3

Option 4

Long acting non-depolarizing (competitive) NM blocking agents require reversal with neostigmine.
Mivacurium is the shortest acting NDMR. It does not require reversal due to its short duration of action.
Mivacurium can be used in day care surgery.

5 Pharmacology

A medication that reduces the rate of aqueous humor formation in acute glaucoma

1) phenothiazines
2) amphotericin B
3) Isoniazid
4) carbonic anhydrase inhibitors

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Option 2

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Option 4

Carbonic anhydrase is found in erythrocytes, kidney, gut, ciliary body, choroid plexus, and glial cells.
Carbonic anhydrase inhibitors are used primarily as probes for studying renal transport mechanisms and in the treatment of glaucoma
When used to treat glaucoma, carbonic anhydrase inhibitors diminish the transport of HCO3 - and Na+ by the ciliary process, which limits intraocular pressure.
This reduces the formation of aqueous humor by up to 50%, thereby reducing the intraocular pressure. These agents can also limit CSF and endolymph formation.

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