MDS PREP
Chlortetracycline acts by interfering with
1. protein synthesis on bacterial but not mammalian ribosomes
2. cell wall synthesis
3. nucleic acid synthesis
4. protein synthesis on mammalian but not bacterial ribosomes
Pharmacology
Answer: 1
Chlortetracycline acts by interfering with protein synthesis on bacterial but not mammalian ribosomes
Penicillinase may inactivate penicillin by splitting the
1. beta-lactum ring
2. benzene ring
3. amide bond
4. thiazolidine ring
Pharmacology
Answer: 1
Penicillinase may inactivate penicillin by splitting the beta-lactum ring
The main excitatory neuro transmitter in CNS is
1) Glycine
2) Acetyl choline
3) Aspartate
4) Glutamate
Pharmacology Answer: 2
The chemical compound acetylcholine (ACh) is a neurotransmitter in both the peripheral nervous system (PNS)and central nervous system (CNS) in many organisms including humans. Acetylcholine is one of many neurotransmitters in the autonomic nervous system (ANS) and the only neurotransmiter used in the somatic nervous system.
Which of the following antibiotics shows an incidence of approximately 8% cross-allergencity with penicillins?
1) Bacitracin
2) Erythromycin
3) Cephalexin
4) Vancomycin
Pharmacology Answer: 3
Cephalosporins can cause allergic reactions in people with penicillin allergy. The overall rate of allergy to cephalosporins in people with penicillin allergy is approximately 5 to 10%, although rates may be higher for certain people. Allergic reactions to cephalosporins can be severe and even lifethreatening;
it is generally recommended that those allergic to penicillin avoid cephalosporins all together.
Drug class causing free water clearance:
a) Diuretic
b) Saluretic
c) Uricosuric
d) Aquaretic
Pharmacology Answer: 4
Vasopressin antagonists like tolvaptan are aquaretics
Which of the following antihypertensive drugs should not be used in a patient on Lithium in order to prevent Lithium Toxicity?
1) Clonidine
2) Beta blockers
3) Calcium Channel Blockers
4) Diuretics
Pharmacology Answer: 4
Diuretics increase sodium loss in urine and increase lithium retention. Hence they should not be used in patients on Lithium.