MDS PREP
Varicose veins may be seen in the
1) Calf
2) Thigh
3) Scrotum
4) All of the above
Oral medicine
Answer: 4
Varicose veins are characterized by twisted, swollen veins that often
appear blue or purple. Common signs and symptoms include aching or heavy
legs, burning or throbbing sensations, muscle cramps, swelling in the lower
legs, and skin changes such as color alterations or sores
Visible Changes:
Twisted, swollen veins that are often blue or dark purple.
Bulging veins that may appear just below the skin surface.
Physical Sensations:
Aching or heavy feeling in the legs.
Burning, throbbing, or cramping sensations, particularly in the
calves.
Swelling in the lower legs and ankles.
Skin Changes:
Color changes in the skin, which may appear red or brown.
Development of sores or ulcers on the skin that do not heal easily.
Scaly or irritated skin that may crack easily.
Other Symptoms:
Restless legs syndrome, which can cause discomfort and an urge to
move the legs.
Pain in the legs or calves after prolonged sitting or standing.
Complications of Varicose Veins
Severe Symptoms:
Increased leg swelling and pain, especially after long periods of
inactivity.
Risk of developing deep vein thrombosis (DVT), which can lead to
serious complications if blood clots form.
Skin Conditions:
Lipodermatosclerosis, a condition that causes inflammation and
hardening of the skin.
Venous ulcers, which are painful sores that can develop due to poor
circulation.
What is the most common site of venous thrombosis in patients with cancer?
1) Superficial veins
2) Cerebral sinuses
3) Deep veins of the lower extremities
4) Hepatic veins
The most common site of venous thrombosis in patients with cancer is the deep veins of the lower extremities, often referred to as deep vein thrombosis (DVT). This is due to a combination of factors such as immobility, cancer-induced hypercoagulability, and damage to the vessels from tumor infiltration or surgery.
In the context of antitubercular therapy, which of the following is true about the metabolism of isoniazid and streptomycin?
(1) Both are metabolized in the liver
(2) Both are metabolized in the kidneys
(3) Isoniazid is metabolized in the liver, while streptomycin is metabolized in the kidneys
(4) Isoniazid is metabolized in the kidneys, while streptomycin is metabolized in the liver
Isoniazid is metabolized by the liver, while streptomycin is metabolized by the kidneys. This is important to consider when administering these drugs, especially in patients with hepatic or renal impairment.
Which of the following is a risk factor for developing atherosclerosis?
1) High HDL cholesterol
2) Low LDL cholesterol
3) High triglycerides
4) Low triglycerides
High triglycerides are a risk factor for atherosclerosis as they contribute to the formation of lipid-rich plaques in the arterial walls.
A patient with severe asthma is prescribed a combination of albuterol and ipratropium. What is the primary mechanism of action for each medication?
(1) Albuterol: beta2-adrenergic agonist; Ipratropium: muscarinic antagonist
(2) Albuterol: muscarinic antagonist; Ipratropium: beta2-adrenergic agonist
(3) Albuterol: beta-adrenergic agonist; Ipratropium: muscarinic antagonist
(4) Albuterol: muscarinic agonist; Ipratropium: beta2-adrenergic antagonist
Albuterol is a beta2-adrenergic agonist that relaxes bronchial smooth muscles, while ipratropium is a muscarinic antagonist that blocks the parasympathetic effects on the airways, leading to bronchodilation.
What is the role of tissue plasminogen activator (tPA) in the treatment of pulmonary embolism?
1) Prevents thrombus formation
2) Dissolves existing thrombi
3) Inhibits platelet aggregation
4) Enhances fibrinolysis
tPA is a thrombolytic agent used to dissolve blood clots. In the treatment of pulmonary embolism, it is administered to break down the clot in the pulmonary artery, thereby improving blood flow and reducing the risk of complications.
A patient with a history of heart failure is prescribed digoxin. Which of the following is a common side effect of digoxin therapy?
(1) Hypertension
(2) Hyperkalemia
(3) Hypokalemia
(4) Hypercalcemia
Digoxin can cause hyperkalemia due to its effect on sodium-potassium ATPase pumps in cardiac cells, leading to increased intracellular sodium and decreased intracellular potassium. However, it is important to note that digoxin can also cause arrhythmias in the presence of high serum potassium levels.
What is the typical age of onset for Huntington's disease?
(1) Childhood
(2) Fourth or fifth decade
(3) Seventh or eighth decade
(4) Second or third decade
Huntington's disease typically begins in the fourth or fifth decade of life. It is an autosomal dominant disorder that affects both men and women, and the symptoms include chorea, behavioral disturbances, and cognitive decline. While there is a wide range in age of onset, the average age of symptom manifestation is around 30 to 50 years.