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NEETMDS- Pathology mcq
MDS PREP
Scleroderma involves 
 1. Tightening of oral mucosa and periodontal involvement
 2. Multiple palmar keratosia
 3. Raynaud"s phenomenon
 4. All of the above
Oral Pathology Answer: 4

Scleroderma involves tightening of oral mucosa, periodontal involvement, and Raynaud's phenomenon.

Quantity of current can be increased by 
 1. Increased milliamperage
 2. Increased time
 3. Increased tube current
 4. All of the above
Oral Pathology Answer: 4

Quantity of current can be increased by increasing milliamperage, time, and tube current.

In sickle cell trait, number of bands found in Hb-
1) 2
2) 1
3) 4
4) 5
General Pathology Answer: 1

In sickle cell trait, the number of bands found in hemoglobin is typically 2, representing both HbA and HbS.

The following protein defects can cause hereditary spherocytosis except -
1) Ankyrin
2) Palladin
3) Glycophorin C
4) Anion transport protein
General Pathology Answer: 3

Glycophorin C is not associated with hereditary spherocytosis; it is a sialoglycoprotein found in the red blood cell membrane, while ankyrin, palladin, and anion transport protein are involved in the structural integrity of the membrane.

Diapedesis Connotes:
1. Pavementing of neutrophils
2. Migration of
neutrophils In tissues
3. Increased urine output
4. Exodus of neutrophils from
vascular compartment


Pathology Answer: 4

Diapedesis is a critical process in the body's immune response, particularly in the context of inflammation.

Paroxymal noctural hemoglobinuria is due to -
1) Acquired red cell defect
2) Congential red cell defect
3) Auto immune defect
4) Lead poisoning
General Pathology Answer: 1

Paroxysmal nocturnal hemoglobinuria is due to an acquired red cell defect, specifically a defect in the cell membrane that makes red blood cells susceptible to lysis.

Letterer-Siwe disease is a disturbance of
1) Protein metabolism
2) Lipid metabolism
3) Mucopolysaccharide metabolism
4) Carbohydrate metabolism
Oral Pathology Answer: 2

Letterer-Siwe disease is a type of Langerhans cell histiocytosis that is associated with disturbances in lipid metabolism.

Letterer-Siwe disease is a form of Langerhans cell
histiocytosis (LCH), which is characterized by the proliferation of
Langerhans cells, a type of dendritic cell involved in immune response. This
disease primarily affects children and can present with a variety of symptoms,
including:

Bone Lesions: Osteolytic bone lesions, particularly in
the skull, vertebrae, and long bones.
Skin Rash: Erythematous lesions or seborrheic
dermatitis-like rashes.
Hematological Abnormalities: Anemia, thrombocytopenia,
and leukopenia may occur.
Organ Involvement: It can affect multiple organs,
including the liver, spleen, and lungs.

Metabolic Disturbance:

Lipid Metabolism: Letterer-Siwe disease is associated
with disturbances in lipid metabolism, particularly due to the accumulation
of lipids in the affected tissues. The Langerhans cells in this condition
can exhibit abnormal lipid storage, which is a hallmark of the disease.


Birbeck’s granules in the cytoplasm are seen in:
1) Langerhans cells
2) Mast cells
3) Myelocytes
4) Thrombocytes
General Pathology Answer: 1

Birbeck’s granules are characteristic of Langerhans cells, which are involved in the immune response and are found in the skin.

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