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Tobacco usage has been associated with 
 1. Hyperkeratosis
 2. Erythema
 3. Ulceration
 4. None of the above
Oral Pathology Answer: 1

Tobacco use, particularly smoking, is known to cause various oral lesions, including hyperkeratosis, which is a thickening of the outer layer of the skin or mucous membranes. This can manifest as leukoplakia or other forms of keratosis in the oral cavity. While tobacco can also lead to erythema and ulceration, hyperkeratosis is the most directly associated condition.

Mitotic delay is longer with 
 1. Smaller dose
 2. Moderate dose
 3. Large dose
 4. A and B
Oral Pathology Answer: 3

Mitotic delay is longer with a large dose of radiation.


Koplik spots
1) First manifestation of measles
2) Rarely seen in measles
3) Are seen 2-3 days after cutaneous rashes
4) Is first manifestation but seldom seen
Oral Pathology Answer: 4

Koplik spots are first manifestation but seldom seen.

Koplik spots are small, white spots with a bluish-white color that appear on the
inside of the cheek opposite the molars in individuals with measles. They are
considered a pathognomonic sign of measles and typically appear 2-3 days before
the onset of the characteristic skin rash. However, they are not commonly
observed in all cases, making them a less frequently seen early manifestation of
the disease. They are small and can be easily overlooked or mistaken for other
oral conditions.

Dentinogenesis imperfecta is always associated with osteogenesis imperfecta in 
 1. Type I
 2. Type II
 3. Type III
 4. All of the above
Oral Pathology Answer: 1

Dentinogenesis imperfecta is always associated with osteogenesis imperfecta in Type I.

Which of the following complement component can be activated in both common as well as alternate pathways?


1) C1


2) C2


3) C3


4) C4

General Pathology Answer: 3

C3 is the complement component that can be activated in both the classical and alternative pathways of the complement system.

What is the effect of hyperparathyroidism on serum and urine calcium levels?

1) Both are decreased
2) Both are normal
3) Serum is elevated, urine is decreased
4) Both are elevated

General Pathology Answer: 4

In hyperparathyroidism, serum calcium levels are elevated due to increased bone resorption, and urine calcium levels are also elevated as the kidneys excrete the excess calcium.

The following protein defects can cause hereditary spherocytosis except -
1) Ankyrin
2) Palladin
3) Glycophorin C
4) Anion transport protein
General Pathology Answer: 3

Glycophorin C is not associated with hereditary spherocytosis; it is a sialoglycoprotein found in the red blood cell membrane, while ankyrin, palladin, and anion transport protein are involved in the structural integrity of the membrane.


Which of the following additional clinical findings would MOST be associated with a woman who has oral mucosal swelling, xerostomia, and intense salivary gland destructive inflammation, as well as antibodies against ribonucleoprotein?

1) Conjunctivitis
2) Goiter
3) Hemolytic anemia
4) Proximal muscle weakness


General Pathology Answer: 1

Conjunctivitis is often associated with Sjögren's syndrome, which can cause oral mucosal swelling and xerostomia.

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