MDS PREP
Orange peel and ground glass radiographic appearance is observed in case of
1. Paget"s disease
2. Ewing"s sarcoma
3. Osteosarcoma
4. Fibrous dysplasia
Orange peel and ground glass radiographic appearance is observed in fibrous dysplasia.
The typical ‘crew cut’ appearance seen in sickle cell anemia because
of:
1. Capillary stasis — decreased blood supply to bone
2. Resorption of marrow leads to expansion of skull bone
3. Expansion of marrow leads to resorption of bone with apposition of new bone
on skull
4. All of the above
Pathology Answer: 3
The expansion of the marrow space due to increased hematopoiesis can lead to resorption of the outer cortical bone and the formation of new bone, resulting in the characteristic "crew cut" appearance on X-rays. This appearance is due to the trabecular pattern of the skull becoming more prominent as the outer layer is resorbed.
Letterer-Siwe disease is a disturbance of
1. Protein metabolism
2. Lipid metabolism
3. Mucopolysaccharide metabolism
4. Carbohydrate metabolism
Oral Pathology
Answer: 2
Letterer-Siwe disease is a disturbance of lipid metabolism.
Which of the following statements is false about Niemann-Pick disease?
1) Type A has bad prognosis
2) Type B has associated organomegaly
3) Chromosome 11 is involved
4) Inherited deficiency of aryl sulfatase is present
General Pathology
Answer: 4
Niemann-Pick disease is characterized by a deficiency of sphingomyelinase, not aryl sulfatase, and involves chromosome 11 in its genetic basis.
Reticulocytosis is seen in -
1) Hemolytic anemia
2) Megaloblastic anemia
3) Aplastic anemia
4) Iron deficiency
General Pathology
Answer: 1
Reticulocytosis is commonly seen in hemolytic anemia, where there is increased production of red blood cells in response to anemia.
Alkaline phosphatase increases in
1. Paget"s disease
2. Osteopetrosis
3. Fibrous dysplasia
4. Both A and D
Oral Pathology
Answer: 4
Alkaline phosphatase increases in both Paget's disease and fibrous dysplasia.
The deficiency of which of the following vitamins does not affect tooth development
1. Vit A
2. Vit D
3. Vit C
4. Vit K
Oral Pathology
Answer: 4
Vitamin K deficiency does not affect tooth development.
In thalassemia the microscopic picture of RBCs is:
1. Microcytic, hypo chromic and target cells present
2. Macrocytic, hypochromic and target cell present
3. Microcytic. hypochromic and target cell absent
4. Macrocytic. hypochromic and target cells absent
Pathology
Answer: 1
Mcroscopic picture of red blood cells (RBCs) in thalassemia, the following
characteristics are typically observed:
Microcytic: The RBCs are smaller than normal (microcytic)
due to the reduced hemoglobin content.
Hypochromic: The RBCs have a lower concentration of
hemoglobin, leading to a paler appearance (hypochromic).
Target cells: These are RBCs that have a bullseye
appearance due to an abnormal distribution of hemoglobin within the cell.
Target cells are often seen in thalassemia due to the imbalance of globin
chains and the resultant membrane changes.