MDS PREP
Asymptomatic facial swelling is seen in
1. Ludwings angina
2. Angioneurotic oedema
3. Bell"s palsy
4. All of the above
Oral Pathology
Answer: 2
Angioneurotic edema is characterized by asymptomatic facial swelling.
The major stimulator of monocytes
1. IL-I
2. ã-interferon
3. IgE
4. lgG
Pathology Answer: 1
1. Interleukin-1 (IL-1): Interleukin-1 is a pro-inflammatory cytokine that
plays a crucial role in the activation and regulation of the immune system. It
is produced mainly by macrophages and monocytes in response to various stimuli,
including bacterial endotoxins, viruses, and tissue damage. IL-1 is a major
stimulator of monocytes, as it promotes their proliferation, differentiation
into macrophages, and enhances their phagocytic and antigen-presenting
capabilities. It also induces the production of other cytokines, such as
TNF-alpha and IL-6, which further amplify the inflammatory response. Thus, it
acts as a critical mediator in the early stages of the immune response and is
involved in the initiation of the acute phase reaction.
2. α-Interferon: Interferons (IFNs) are a family of cytokines that play an
essential role in the innate immune response to viral infections. They are
mainly produced by cells in response to viral infection and can induce an
antiviral state in nearby cells by upregulating the expression of proteins that
inhibit viral replication. While α-interferon does not directly stimulate
monocytes, it does have some effects on the immune system, such as enhancing the
natural killer (NK) cell activity and modulating the function of macrophages and
other immune cells. However, it is not the primary stimulator of monocytes like
IL-1 is.
3. Immunoglobulin E (IgE): IgE is a class of antibodies that are involved in the
allergic response and the immune response to parasites. It is produced in
response to allergens and parasitic antigens. While IgE is important in the
activation of mast cells and basophils, which play a key role in the immediate
allergic response, it does not serve as a major stimulator of monocytes.
Monocytes are more closely associated with the innate immune response and are
not primarily activated by antibodies.
4. Immunoglobulin G (IgG): IgG is the most abundant and versatile class of
antibodies in the blood. It plays a pivotal role in the immune response by
binding to pathogens and facilitating their destruction through various
mechanisms, such as opsonization (enhancing phagocytosis), activation of the
complement system, and neutralization of toxins. IgG can interact with
macrophages via Fcγ receptors, which can lead to phagocytosis of
antigen-antibody complexes. However, IgG is not a direct stimulator of monocytes
in the same sense that IL-1 is. Monocytes are primarily activated by cytokines
and other signaling molecules released during inflammation and infection, rather
than by antibodies.
The antecedents of Sq. cell carcinoma is/are:
1. Leukoplakia
2. Solar keratosis
3. Margins of long standing draining sinuses
4. All of the above
Pathology
Answer: 4
All of the listed conditions (leukoplakia, solar keratosis, and margins of long-standing draining sinuses) are known precursors to squamous cell carcinoma.
Which of the following has the potential of undergoing spontaneous malignant transformation
1. Osteomalacia
2. Albright"s syndrome
3. Paget"s disease of bone
4. Osteogenesis imperfecta
Oral Pathology
Answer: 3
Paget's disease of bone has the potential for spontaneous malignant transformation.
Oral manifestation of infectious mononucleosis is most commonly
1. Bluish red spots opposite maxillary molar
2. Pseudomembrane on gingival
3. Pinpoint petechiae on the palate
4. Gingival hyperplasia
Oral Pathology
Answer: 3
Pinpoint petechiae on the palate is the most common oral manifestation of infectious mononucleosis.
When treated with simple curettage which odontogenic tumour is most likely to recur
1) Complex odontoma
2) Compound odonotoma
3) Odentogenic myxoma
4) Ameloblastic fibroma
Oral Pathology
Answer: 3
Explanation: Odontogenic myxoma is known for its aggressive behavior and tendency to recur after treatment, including curettage. It is a benign but locally invasive tumor, and simple curettage often does not remove the entire tumor, leading to recurrence.
A young patient who has a long standing habit of sucking lemons has loss of tooth substance affecting the anterior teeth. The correct term for this gradual loss of tooth substance is called
1. Abrasion
2. Attrition
3. Erosion
4. Intrusion
Oral Pathology
Answer: 3
The gradual loss of tooth substance due to sucking lemons is called erosion.
What condition is typically characterized by a malar rash, arthritis, serositis, and the presence of antinuclear antibodies?
1) Goodpasture's syndrome
2) Friedreich ataxia
3) Huntington's disease
4) Systemic lupus erythematosus (SLE)
Systemic lupus erythematosus (SLE) is characterized by a malar rash, arthritis, serositis, and the presence of antinuclear antibodies.