MDS PREP
Glycolysis occurs in:
1. Cytoplasm
2. Mitochondrion
3. Both In cytoplasm and mitochondria
4. Only in presence of O2
Biochemistry
Answer: 1
Glycolysis is a metabolic process that occurs in the cytoplasm of the cell.
The process is central to the conversion of glucose into energy in the form of
adenosine triphosphate (ATP) and is a fundamental part of cellular respiration.
1. Cytoplasm: Glycolysis takes place in the cytoplasm of the cell. The cytoplasm
is the fluid-filled space between the cell membrane and the nucleus (and other
organelles in eukaryotes) where various metabolic reactions occur. This process
involves a series of enzymatic reactions that break down one molecule of glucose
into two molecules of pyruvate, yielding two net molecules of ATP and two
molecules of NADH (a reduced form of nicotinamide adenine dinucleotide) along
with some other byproducts.
2. Mitochondrion: Although glycolysis does not occur in the mitochondrion, the
mitochondrion plays a crucial role in the subsequent stages of glucose
metabolism. After glycolysis, the pyruvate molecules produced in the cytoplasm
can be transported into the mitochondria, where they are further processed in
the citric acid cycle (also known as the Krebs cycle or TCA cycle) and the
electron transport chain to produce more ATP.
The lipids associated with very low density lipoprotein
1. are usually linked covalently to apoproteins.
2. belong primarily to the phosphatidylcholine class.
3. incorporate fatty acids that are synthesized in the liver.
4. reflect, in general, the types of lipids found in the diet.
Biochemistry
Answer: 3
VLDL is a lipoprotein particle synthesized in the liver and secreted into the bloodstream to transport endogenously synthesized triglycerides and cholesterol to peripheral tissues. The triglycerides in VLDL are derived from fatty acids synthesized in the liver, and the cholesterol is derived from both dietary sources and de novo synthesis in the liver. They are not usually linked covalently to apoproteins (Answer 1), nor do they primarily consist of phosphatidylcholine (Answer 2). While the types of lipids found in the diet (Answer 4) can influence the liver's synthesis of VLDL, the statement does not accurately describe the direct composition of VLDL.
Features of Vitamin C deficiency is due to defect of which enzyme
1. Lysyl hydroxylase
2. Lysyl oxidase
3. Procollagen peptidase
4. None of the above
Biochemistry
Answer: 1
Vitamin C deficiency is due to defect of Lysyl hydroxylase
In addition to the influence of the oxygen concentration, the formation of oxyhemoglobin is influenced by
1. pH
2. CO2 concentration
3. Temperature
4. All of the above
Biochemistry
Answer: 4
The formation of oxyhemoglobin is influenced by
1. pH
2. CO2 concentration
3. Temperature
The immunoglobulin secreted in Bile is
1. IgG
2. 1gM
3. IgA
4. IgE
Biochemistry
Answer: 3
The immunoglobulin secreted in Bile is IgA
Anemia is frequently associated with a deficiency of
1. vitamins A and D.
2. vitamins C and D.
3. vitamins E and K.
4. vitamin B12 and folic acid.
Biochemistry
Answer: 4
Anemia is a condition characterized by a decrease in the number of red blood
cells or a reduction in their oxygen-carrying capacity. Vitamin B12 and folic
acid are essential for the production of red blood cells. Deficiencies in these
vitamins can lead to megaloblastic anemia, where the bone marrow produces
abnormally large and immature red blood cells.
Which of the following dental tissues is most likely to be effected by Vit-A
deficiency
1. enamel
2. dentin
3. cementum
4. pulp
Biochemistry Answer: 1
Enamel most likely effected by deficiency of vitamin A
Gout is a disease of purine overproduction. In this disease, joints develop crystals of
1. urea.
2. sodium urate.
3. guanine.
4. hypoxanthine.
Biochemistry
Answer: 2
Gout is a form of arthritis caused by the accumulation of uric acid crystals,
specifically sodium urate crystals, in the joints. The body produces uric acid
as a waste product during the metabolism of purines, which are substances found
in certain foods and also synthesized by the body. High levels of uric acid can
lead to the formation of these crystals, which cause inflammation and pain in
the affected joints. Urea (Answer 1) is a waste product formed from the
metabolism of proteins and amino acids, while guanine (Answer 3) and
hypoxanthine (Answer 4) are purine bases involved in nucleotide metabolism, but
they do not directly form the crystals seen in gout.