MDS PREP
Crew haircut appearance in X-ray skull and Gamna Gandy bodies are seen in -
1) G-6-PD deficiency
2) Hodgkin's lymphoma
3) Hereditary spherocytosis
4) Sickle cell anaemia
General Pathology
Answer: 4
Crew haircut appearance in X-ray skull and Gamna Gandy bodies are associated with sickle cell anemia due to chronic hemolysis and bone marrow hyperplasia.
A disease which only affects the formation and eruption of tooth but does not cause hypoplasia is
1. Hypoparathyroidsm
2. Hyperthyroidism
3. Hyperpituitarism
4. Hypoadrenalism
Oral Pathology
Answer: 3
Hyperpituitarism affects the formation and eruption of teeth without causing hypoplasia.
What is the primary lesion associated with an increased risk of adenocarcinoma of the distal esophagus?
1) Generalized fatigue
2) Goodpasture's syndrome
3) Barrett's esophagus
4) Sarcoma
Barrett's esophagus is the primary lesion associated with an increased risk of adenocarcinoma of the distal esophagus.
A wound which Was sutured attains:
1. Normal tensile strength after 6 months
2. 70-80% of tensile strength of unwounded skin which may persist for life
3. 100% tensile strength of unwounded skin after 9 months
4. 100% of tensile strength can be achieved if sutures were of nylon or vicryl
Pathology Answer: 2
The newly formed collagen in the scar tissue is arranged differently compared to the organized collagen fibers in the unwounded skin, leading to a weaker structure. The 70-80% tensile strength is typically what is seen in well-healed sutured wounds. This remaining deficit is because scar tissue is less elastic and more prone to dehiscence (reopening) under tension compared to normal skin.
Recurrent ulcers occuring on gingival and palate are most probably
1) Aphthous ulcers
2) Herpes simplex
3) Koplick spots
4) Lesions of Behcet"s syndrome
Oral Pathology
Answer: 2
Recurrent ulcers on the gingiva and palate are most commonly associated with herpes simplex virus (HSV) infections. Herpes simplex can cause painful vesicular lesions that eventually ulcerate, leading to recurrent oral ulcers, particularly in the mucosal areas such as the gingiva and palate.
Aphthous ulcers (option 1) typically occur on non-keratinized mucosa and are not usually found on the gingiva. Koplick spots (option 3) are associated with measles and are not ulcers but rather small, bluish-white spots on the buccal mucosa. Behcet's syndrome (option 4) can cause oral ulcers, but they are often more widespread and associated with systemic symptoms. Therefore, the most probable cause of recurrent ulcers specifically on the gingiva and palate is herpes simplex.
A patient exhibits radiolucent areas in the jaw bones which stimulate both periapical and periodontal lesions. The serum calcium is 13.5 mg% and serum phosphorus is 2.3 mg%. A biopsy from one of the radiolucent areas reveals a giant cell lesion. The most likely diagnosis is
1. Hyperparathyroidism
2. Hypoparathyroidism
3. Hultiple myeloma
4. Muxoedema
Oral Pathology
Answer: 1
The most likely diagnosis for the patient is hyperparathyroidism, given the symptoms and lab findings.
Commonest type of Basal cell carcinoma is -
1. Ulcerated
2. Cystic
3. Morphoeic
4. Pigmented
Pathology
Answer: 1
1. Noduloulcerative Basal Cell Carcinoma: This is the most common subtype of
BCC, making up about 60-70% of all cases. It typically appears as a slowly
growing, round to oval, pearly or translucent nodule with a central ulceration
that may bleed or ooze. The borders of the lesion are often not well-defined and
may have a rolled, pearly edge with telangiectasias (small, dilated blood
vessels).
2. Cystic Basal Cell Carcinoma: This subtype presents as a round, dome-shaped
lesion with a cystic or fluid-filled center. It is less common than the
noduloulcerative type, and it may be mistaken for a benign cyst or epidermoid
cyst.
3. Morphoeic Basal Cell Carcinoma: Also known as sclerosing or morpheaform BCC,
this type is characterized by a slowly growing, ill-defined, firm, plaque-like
lesion that can infiltrate deeply into the skin. It may have a whitish, waxy
appearance with a scar-like texture. Morphoeic BCC tends to be more aggressive
and can be challenging to diagnose due to its subtlety.
4. Pigmented Basal Cell Carcinoma: This is a less common variant of BCC,
accounting for approximately 6-15% of cases. It presents with pigmentation in
the lesion, which can be brown, blue, or black. The presence of pigment can make
it look similar to melanoma, another type of skin cancer, so a biopsy is often
necessary to confirm the diagnosis.
Yellowish discolouration of oral mucous membrane, skin and sclera of eye is
1. Pernicious anaemia
2. Sickle cell anaemia
3. Chloromycin therapy
4. Carotinemia
Oral Pathology
Answer: 4
Yellowish discoloration of the oral mucous membrane, skin, and sclera of the eye is seen in carotinemia.