MDS PREP
Which of the following is NOT a clinical sign associated with Bell's palsy?
(1) Paralysis of the lower part of the face only.
(2) Inability to close the affected eye completely.
(3) Preservation of the ability to wrinkle the forehead.
(4) Impaired articulation of labial sounds.
Bell's palsy typically involves the entire side of the face, not just the lower part. The affected side may become asymmetric and motionless, with wrinkles disappearing from the forehead and an inability to close the eye completely. Impaired articulation of labial sounds is a common symptom due to the involvement of the facial muscles used for speech.
What is the prevalence of Huntington's disease in the general population?
1) 1/1000
2) 1/10,000
3) 1/100,000
4) 1/1,000,000
Huntington's disease has a prevalence of approximately 10 per 100,000 people in the general population. It is more common in certain ethnic groups, particularly those of Western European descent.
What is the primary action of acetaminophen?
1) Anti-inflammatory
2) Analgesic and antipyretic
3) Muscle relaxant
4) Antihypertensive
Acetaminophen is primarily known for its analgesic and antipyretic (fever-reducing) effects. It is a common component in many over-the-counter pain relief medications.
A patient with severe nausea and vomiting is prescribed metoclopramide. What is the primary mechanism of action of metoclopramide?
(1) Antihistaminic action
(2) Dopamine antagonism in the CNS
(3) Muscarinic receptor antagonism
(4) 5-HT3 receptor antagonism
Metoclopramide acts primarily as a dopamine D2 receptor antagonist in the chemoreceptive trigger zone in the brain and in the gastrointestinal tract, which helps to reduce nausea and vomiting by decreasing gastric emptying and increasing gastric tone.
What is the target INR range for a patient on warfarin therapy to undergo minor oral surgery?
(1) Less than 2
(2) 2-3
(3) 3-4
(4) Less than 1.5
For a patient on warfarin therapy, the target INR (International Normalized Ratio) for undergoing minor oral surgery is typically 2-3. This range provides adequate thromboprophylaxis while minimizing the risk of excessive bleeding. However, the decision to proceed with surgery should be made on a case-by-case basis, considering the patient's overall health and surgical risks.
What is the primary defect in familial hypokalemic periodic paralysis?
1) Marked increase in muscle potassium permeability
2) Marked decrease in muscle sodium permeability
3) Marked decrease in muscle potassium permeability
4) Impaired sodium-potassium pump function
In familial hypokalemic periodic paralysis, the primary defect is a decrease in muscle potassium permeability, leading to a reduced efflux of potassium from muscle cells.
Which of the following is a true statement about amylase levels in pleural fluid?
(1) High amylase levels in pleural fluid indicate a pancreatic origin of the effusion
(2) High amylase levels in pleural fluid are always due to esophageal rupture
(3) High amylase levels in pleural fluid can be seen in both pancreatic and esophageal rupture
(4) High amylase levels in pleural fluid are diagnostic of pulmonary tuberculosis
High amylase levels in pleural fluid can indicate either a pancreatic or an esophageal origin of the effusion. It is not specific to one condition and further diagnostic tests are needed to determine the source.
What is the treatment for respiratory alkalosis?
1) Inhalation of carbon dioxide
2) Injection of sodium bicarbonate
3) Ingestion of antacids
4) Increase in respiratory rate
The treatment for respiratory alkalosis typically involves correcting the underlying cause. However, if symptoms are severe, inhalation of a small amount of carbon dioxide can be administered.