MDS PREP
Bence Jones proteins are seen in
1. Uraemia
2. Diabetes mellitus
3. Polycythaemia vera
4. Mediterranean anaemia
Oral Pathology
Answer: 3
Bence Jones proteins are seen in multiple myeloma, not polycythemia vera.
Precancerous potential in Plummer-Vinson syndrome may be due to change in the epithelium like
1. Atrophy
2. Hypertrophy
3. Acanthosia
4. All the above
Oral Pathology
Answer: 1
Plummer-Vinson syndrome is associated with atrophic changes in the
epithelium, which can lead to an increased risk of cancer
Plummer-Vinson syndrome is characterized by a classic triad of
clinical features: dysphagia (difficulty swallowing), iron-deficiency anemia,
and esophageal webs. Additional symptoms may include glossitis (inflammation of
the tongue), koilonychia (spoon-shaped nails), and cheilitis (inflammation of
the lips).
Clinical Features of Plummer-Vinson Syndrome:
Dysphagia:
Difficulty swallowing due to the presence of esophageal webs, which
can obstruct the esophagus.
Iron-Deficiency Anemia:
Resulting from chronic blood loss or malabsorption, leading to
fatigue and weakness.
Esophageal Webs:
Thin membranes that form in the esophagus, contributing to
swallowing difficulties.
Glossitis:
Inflammation of the tongue, which may appear smooth and swollen.
Koilonychia:
Spoon-shaped nails that can indicate iron deficiency.
Cheilitis:
Inflammation and cracking of the lips, often associated with
nutritional deficiencies.
Fatigue and Weakness:
Common symptoms due to anemia and nutritional deficiencies.
Associated Risks:
Esophageal Cancer:
There is an increased risk of developing esophageal cancer in
individuals with Plummer-Vinson syndrome.
Prevention:
Iron Intake:
Ensuring adequate dietary iron may help prevent the onset of this
syndrome. Diagnosis and Management:
Diagnosis:
Diagnosis is typically made through clinical evaluation, endoscopy,
and imaging studies to identify esophageal webs and assess for anemia.
Management:
Treatment often involves iron supplementation to address anemia and
dietary modifications to improve iron intake. In some cases, dilation of
esophageal webs may be necessary to alleviate dysphagia
Which of the following cell types show abnormal function when there is a history in a young adult of multiple arm and leg fractures following minor falls, with a slight weakness of facial muscles on the left, mild anemia, and with generalized bony widening with partial obliteration of marrow spaces?
1) Granulocytic stem cells
2) Megakaryocytes
3) Plasma cells
4) Osteoclasts
General Pathology Answer: 4
Osteoclasts show abnormal function in conditions leading to multiple fractures, as they are responsible for bone resorption.
Grid is used
1. To remove secondary radiation
2. Filter the radiation
3. Removes scattered radiation
4. None of the above
Oral Pathology
Answer: 3
Grids are used to remove scattered radiation from the X-ray beam.
Which of the following is true regarding seminoma?
1) 40% cases occur in children <1 year of age
2) Alpha fetoprotein can be used as a marker
3) Dysgerminoma is its ovarian counterpart
4) All of the above statements are true
General Pathology Answer: 3Dysgerminoma is the ovarian counterpart of seminoma, which is a germ cell tumor found in the testes.
The residual biologic damage tha remains following an exposure to radiation is called
1. Direct effect
2. Indirect effect
3. Cumulative effect
4. Tolerance
Oral Pathology
Answer: 3
The residual biological damage that remains following exposure to radiation is called cumulative effect.
All of the following statements about idiopathic thrombocytopenic purpura are true except
1. It is associated with platelet-specific autoantibodies
2. It causes a prolonged bleeding time
3. It is often controllable by immunosuppressive treatment
4. It causes more prolonged haemorrhage than haemophilia
Oral Pathology Answer: 4
It is associated with platelet-specific autoantibodies:
This statement is true. ITP is characterized by the
presence of autoantibodies that specifically target and destroy platelets,
leading to thrombocytopenia (low platelet count).
It causes a prolonged bleeding time: This statement is true.
In ITP, the low platelet count results in a prolonged bleeding time, as
there are fewer platelets available to form a clot.
It is often controllable by immunosuppressive treatment:
This statement is true. ITP can often be managed with
immunosuppressive therapies, such as corticosteroids, intravenous
immunoglobulin (IVIG), or other immunosuppressive agents, to help increase
platelet counts.
It causes more prolonged hemorrhage than hemophilia:
This statement is not true. While both ITP and hemophilia
can lead to bleeding, the mechanisms are different. Hemophilia is a clotting
factor deficiency, which can lead to more severe and prolonged bleeding
episodes, especially after trauma or surgery. In contrast, ITP primarily
affects the number of platelets rather than the clotting factors. Therefore,
the bleeding in hemophilia can be more severe and prolonged compared to that
in ITP.
Reversible pulpitis change to irreversible pulpits primarily because of
1) Vascular strangulation
2) Reduced host resistance
3) Invasion of microorganisms
4) An increase in microbial virulence
Oral Pathology
Answer: 3
Reversible pulpitis changes to irreversible pulpitis primarily because of
invasion of microorganisms.
Reversible pulpitis is a condition where the pulp is inflamed but can
potentially heal if the causative agent is removed and the pulp remains vital.
Irreversible pulpitis, however, occurs when the inflammation is severe or
chronic, leading to irreversible damage to the pulp. The primary reason for this
progression is typically the invasion of microorganisms and their byproducts,
which can cause further inflammation and necrosis of pulpal tissue, making
healing unlikely.