MDS PREP
Gingiva is most commonly affected by deficiency of
1. Vitamin A
2. Vitamin D
3. Vitamin C
4. Vitamin B
Oral Pathology
Answer: 3
Gingiva is most commonly affected by a deficiency of Vitamin C.
What is the typical clinical presentation of a patient with a gastrinoma?
1) Sudden painful enlargement of the thyroid
2) Severe abdominal pain, diarrhea, and hypercalcemia
3) Hypoglycemic episodes and abdominal pain
4) Patches of erythematous mucosa in the stomach
Severe abdominal pain, diarrhea, and hypercalcemia are typical clinical presentations of a gastrinoma.
Cafe-au-lait spots are seen in
1. Paget"s disease of bone
2. Cherubism
3. Von Recklinghausen disease
4. Von Willebrand disease
Oral Pathology
Answer: 3
Cafe-au-lait spots are seen in Von Recklinghausen disease.
Which of the following proteins is most likely under-expressed in this boy?
1) Late complement components
2) Transcobalamin II
3) Integrins
4) ?2-globulins
General Pathology
Answer: 3
Integrins are likely under-expressed in this boy, as they play a crucial role in cell adhesion and signaling, and their deficiency can lead to various immunological issues.
Which of the following complement component can be activated in both common as well as alternate pathways?
1) C1
2) C2
3) C3
4) C4
General Pathology Answer: 3C3 is the complement component that can be activated in both the classical and alternative pathways of the complement system.
Oral lesions on the tongue and other mucosal surfaces of the oral cavity is commonly caused by the deficiency of
1. Vit B
2. Niacin
3. Vit C
4. Vit K
Oral Pathology
Answer: 2
Oral lesions on the tongue are commonly caused by a deficiency of Niacin (Vitamin B3).
Recurrent ulcers occuring on gingival and palate are most probably
1) Aphthous ulcers
2) Herpes simplex
3) Koplick spots
4) Lesions of Behcet"s syndrome
Oral Pathology
Answer: 2
Recurrent ulcers on the gingiva and palate are most commonly associated with herpes simplex virus (HSV) infections. Herpes simplex can cause painful vesicular lesions that eventually ulcerate, leading to recurrent oral ulcers, particularly in the mucosal areas such as the gingiva and palate.
Aphthous ulcers (option 1) typically occur on non-keratinized mucosa and are not usually found on the gingiva. Koplick spots (option 3) are associated with measles and are not ulcers but rather small, bluish-white spots on the buccal mucosa. Behcet's syndrome (option 4) can cause oral ulcers, but they are often more widespread and associated with systemic symptoms. Therefore, the most probable cause of recurrent ulcers specifically on the gingiva and palate is herpes simplex.
Precancerous potential in Plummer-Vinson syndrome may be due to change in the epithelium like
1. Atrophy
2. Hypertrophy
3. Acanthosia
4. All the above
Oral Pathology
Answer: 1
Plummer-Vinson syndrome is associated with atrophic changes in the
epithelium, which can lead to an increased risk of cancer
Plummer-Vinson syndrome is characterized by a classic triad of
clinical features: dysphagia (difficulty swallowing), iron-deficiency anemia,
and esophageal webs. Additional symptoms may include glossitis (inflammation of
the tongue), koilonychia (spoon-shaped nails), and cheilitis (inflammation of
the lips).
Clinical Features of Plummer-Vinson Syndrome:
Dysphagia:
Difficulty swallowing due to the presence of esophageal webs, which
can obstruct the esophagus.
Iron-Deficiency Anemia:
Resulting from chronic blood loss or malabsorption, leading to
fatigue and weakness.
Esophageal Webs:
Thin membranes that form in the esophagus, contributing to
swallowing difficulties.
Glossitis:
Inflammation of the tongue, which may appear smooth and swollen.
Koilonychia:
Spoon-shaped nails that can indicate iron deficiency.
Cheilitis:
Inflammation and cracking of the lips, often associated with
nutritional deficiencies.
Fatigue and Weakness:
Common symptoms due to anemia and nutritional deficiencies.
Associated Risks:
Esophageal Cancer:
There is an increased risk of developing esophageal cancer in
individuals with Plummer-Vinson syndrome.
Prevention:
Iron Intake:
Ensuring adequate dietary iron may help prevent the onset of this
syndrome. Diagnosis and Management:
Diagnosis:
Diagnosis is typically made through clinical evaluation, endoscopy,
and imaging studies to identify esophageal webs and assess for anemia.
Management:
Treatment often involves iron supplementation to address anemia and
dietary modifications to improve iron intake. In some cases, dilation of
esophageal webs may be necessary to alleviate dysphagia