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NEET MDS Shorts

40499
General Medicine

In developing countries, the most common cause of primary adrenal insufficiency is tuberculosis, due to its higher prevalence and ability to spread to various organs, including the adrenal glands.

97164
Pharmacology

Dimercaprol (British antilewisite; BAL)  

1. Poisoning by As, Hg, Au, Bi, Ni, Sb: it is administered i.m., 5 mg/kg stat, followed by 2-3 mg/kg every 4 – 8 hours for 2 days, then once or twice a day for 10 days. It is partly oxidized and glucuronide conjugated, but mainly excreted as such in 4 – 6 hours. Earlier the treatment is instituted, the better it is. Because the dimercaprolmetal complex dissociates faster in acidic urine and the released metal can damage the kidney, urine is alkalinized during dimercaprol therapy. 

2. As an adjuvant to Cal. Disod. Edentate in lead poisoning. 

3. As an adjuvant to penicillamine in Cu poisoning and in Wilson’s disease – 300 mg/day i.m. for 10 days every second month.  

It is contraindicated in iron and cadmium poisoning, because the dimercaprol-Fe and dimercaprol-Cd complex is itself toxic.

63063
Oral Pathology

Myositis ossificans generalisata (fibrodysplasia ossificans progressiva) causes progressive ossification of muscles, tendons, and ligaments, leading to a "petrified" or stone-like condition where the patient becomes immobilized. This rare genetic disorder progressively restricts movement as soft tissues calcify. Dystrophic myotonia, dermatomyositis, and proliferative myositis do not cause this petrification process.

58128
Radiology

Double intensifying screens with screen film significantly reduce exposure time by amplifying the X-ray effect. The screens convert X-ray photons to light photons, which expose the film more efficiently than direct X-ray exposure. This reduces radiation dose to the patient while maintaining image quality.

84215
Oral Pathology

Anitschow's cells, also known as "caterpillar cells," are a type of histiocyte that can be found in the context of certain inflammatory conditions, including aphthous ulcers. These cells are indicative of a specific immune response and are often associated with the healing process of these painful oral lesions.

51469
Physiology

In the sympathetic nervous system, the pre-to-post ganglionic fiber ratio of 1:20 to 1:100 indicates that there are fewer postganglionic fibers than preganglionic fibers. This ratio suggests that each preganglionic neuron synapses with multiple postganglionic neurons, thereby amplifying the sympathetic response to a given input.

44156
Dental Anatomy

A mandibular primate space is usually found in the primary dentition between canine and first molar

68043
INI CET

Pain that disappears immediately after the removal of a stimulus (like cold) is indicative of reversible pulpitis or dentin hypersensitivity, which is treated conservatively with desensitizing agents.

60992
Medicine

PEP should be started as soon as possible (preferably within 2 hours, and not later than 72 hours).

The duration is 28 days (4 weeks).

The recommended regimen is a triple-drug combination to maximize efficacy and reduce the risk of resistance.

Zidovudine (AZT) + Lamivudine (3TC): These are nucleoside reverse transcriptase inhibitors (NRTIs) and form the backbone of most HIV prophylaxis regimens.

Indinavir: A protease inhibitor, added to strengthen the regimen and provide a third mechanism of action.

Together, this triple therapy is recommended for occupational exposure to HIV-positive blood

21363
Oral Pathology

A large tongue is a common feature of acromegaly.

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