NEET MDS Shorts
98141
Pharmacology
Tyrosine kinase inhibitors are used in the treatment of: Chronic myeloid leukemia
Acute lymphoblastic leukemia ( philadelphia chromosome positive cases )
Head and neck malignancies
Non small cell carcinoma lung
Gastrointestinal stromal tumours
Hepatocellular cancer
Renal cell carcinoma
Pancreatic cancer
Colorectal cancer
85770
Pharmacology
Morphine is contraindicated in head injury for the following reasons: Causes carbondioxide retention – this in turn increases intracranial tension
Therapeutic doses can cause respiratory depression in head injury patients Vomiting, miosis and altered mentation caused by morphine can interfere with assessment of neurological status
Morphine should be avoided in those with bronchial asthma as it can precipitate an attack of asthma. But it is not contraindicated
69365
Pharmacology
Other drugs with narrow therapeutic index:
Digoxin Gentamicin Amphotericin B Levothyroxine Prazosin Theophylline Quinidine Warfarin Valproic acid
41205
PharmacologyCarbamazepine is the primary and most effective medication used to treat trigeminal neuralgia. It is an anticonvulsant drug that works by reducing nerve impulses that cause pain.
11314
Pharmacology
Functions of delta type opioid receptors are: supraspinal analgesia
spinal analgesia
modulation of hormone and neurotransmitter release
65646
Pharmacology
Cephalosporins can cause allergic reactions in people with penicillin allergy. The overall rate of allergy to cephalosporins in people with penicillin allergy is approximately 5 to 10%, although rates may be higher for certain people. Allergic reactions to cephalosporins can be severe and even lifethreatening;
it is generally recommended that those allergic to penicillin avoid cephalosporins all together.
48846
Pharmacologyless solublity in blood means more rapid induction, however quicker emergence after discontinuing depends upon solublity and redistribution in lipids of body as well
53955
PharmacologyMorphine causes vomiting by stimulation of the medullary chemo receptor trigger zone
27133
Pharmacology
Chlorthalidone (Thiazide like diuretic)
13951
PharmacologyChlortetracycline acts by interfering with protein synthesis on bacterial but not mammalian ribosomes