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Benzodiazepines: Produce anterograde amnesia Act on α-subunit of GABA-A receptors Muscle relaxation with Midazolam Flumazenil: Specific antagonist Lorazepam: Difficult reversal…
Morphine: MC cause of death → Respiratory depression ↑ ICP ❌ No muscle relaxation Opioids act on dorsal horn of spinal cord Diazepam for post-op delirium…
Pain: sensory and emotional experience associated with actual or potential tissue damage 1. Components: sensory (objective characteristics of pain e.g., location, duration, intensity; thermal, mechanical, or chemical) and motivational/affective (associated with past experience, fear, suffering, anxiety, culture) 2. Anatomy and physiology: nociceptors specialized to convey noxious stimuli (mechanical, chemical, thermal) a. Hyperalgesia: …
First Local Anaesthetic: Cocaine First Muscle Relaxant: D-Tubocurarine (DTC) Intubation Pioneer: Ivan Magill (Magill's forceps) Preoperative Considerations Stop smoking ideally 8 weeks prior to surgery. Urgent warfarin reversal: Fresh Frozen Plasma (FFP). Atropine: ↓ Salivation Bronchodilation Flushing in pediatric patients…
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NEET MDS