Study Notes

Papillon-Lefevre Syndrome Classic Triad Plantar Hyperkeratosis: Thickening of palms and soles Early-Onset Periodontitis: Severe periodontal destruction in primary and permanent dentition Dural Calcification: Intracranial calcifications Genetics and Pathogenesis Inheritance: Autosomal recessive Gene: CTSC gene mutation affecting cathepsin C Drug-Induced Gingival Hyperplasia Most Common Causative Drug Primary Agent: Phenytoin (anti-seizure…

Innervation of the Pharynx The motor and most of the sensory supply of the pharynx is derived from the pharyngeal plexus of nerves on the surface of the pharynx. The plexus is formed by pharyngeal branches of the vagus (CN X) and glossopharyngeal (CN IX) nerves, and by sympathetic branches for the superior cervical ganglion. The motor fibres in the pharyngeal plexus are derived from the cranial root of accessory nerve (CN XI), and are carried by the…

Niacin: Vitamin B3, Nicotinamide, Nicotinic Acid Niacin, or vitamin B3,  is involved in energy production, normal enzyme function, digestion, promoting normal appetite, healthy skin, and nerves. RDA Males: 16 mg/day; Females: 14 mg/day Niacin Deficiency : Pellagra is the disease state that occurs as a result of severe niacin deficiency. Symptoms include cramps, nausea, mental confusion, and skin problems.…

Diseases from Str. pyogenes (Group A strep) 1.  Streptococcal pharyngitis.  Most frequent Group A infection.  Throat has gray-white exudate.  Infection may become systemic into blood, sinuses, jugular vein, meninges.  In less than a week the M-protein and capsule production decrease, and transmission declines. 2.  Skin infections, such as impetigo.  Especially in children.  Different M-proteins than in pharyngitis. …

Adult Respiratory Distress Syndrome  A constellation of pathologic and clinical findings initiated by diffuse injury to alveolar capillaries. This syndrome is associated with a multitude of clinical conditions which primarily damage the lung or secondarily as part of a systemic disorder.  Pathogenesis  There are many types of injuries which lead to the ultimate, common pathway, i.e., damage to the alveolar capillary unit. The initial injury most …