• Ossification

• Intramembranous-found in the flat bones of the face
  • Mesenchymal cells cluster and form strands
  • Strands are cemented in a uniform network. Which is known as osteoid
  • Calcium salts are deposited; osteoid is converted to bone
  • Trabeculae are formed and make cancellous bone with open spaces known as marrow cavities
  • Periosteum forms on the inner and outer surfaces of the ossification centers
  • Surface bone becomes compact bone
• Endochondral-primary type of ossification In the human

The Orbital Margin

• The frontal, maxillary and zygomatic bones contribute equally to the formation of the orbital margin.

• The supraorbital margin is composed entirely of the frontal bone.
• At the junction of its medial and middle thirds is the supraorbital foramen (sometimes a notch), which transmits the supraorbital nerves and vessels.

• The lateral orbital margin is formed almost entirely of the frontal process of the zygomatic bone.

• The infraorbital margin is formed by the zygomatic bone laterally and the maxilla medially.

• The medial orbital margin is formed superiorly by the frontal bone and inferiorly by the lacrimal crest of the frontal process of the maxilla.
• This margin is distinct in its inferior half only.

The Arteries of the Face

• The superficial arteries are derived from the external carotid arteries.

The Facial Artery

• This is the chief artery of the face.
• It arises from the external carotid artery and winds its way to the inferior border of the mandible, just anterior to the masseter muscle.
• It hooks around the inferior border of the mandible and grooves the bone. Here the artery is superficial, just beneath the platysma and its pulsation can be felt.

• In its course over the face to the medial angle of the eye, the facial artery crosses the mandible, buccinator muscle, and maxilla.
• It lies deep to the zygomaticus major.

• The facial artery ends by sending branches to the lip and side of the nose.
• The part of the artery that runs along the side of the nose to supply the eyelids is called the angular artery.

The Superficial Temporal Artery

• This artery is the smaller of the two terminal branches of the external carotid artery (the other is the maxillary artery).
• It begins deep to the parotid gland, posterior to the neck of the mandible, and ascends superficial to the posterior end of the zygomatic process of the temporal bone. It then enters the temporal fossa.

• The superficial temporal artery ends in the scalp by dividing into the frontal and parietal branches.

• Pulsation of this artery can be felt by compressing the root of the zygomatic process of the temporal bone.

The Transverse Facial Artery

• This small artery arises from the superficial temporal artery before it emerges from the parotid gland.
• It crosses the face superficial to the masseter muscle, about a fingerbreadth inferior to the zygomatic arch.
• It divides into numerous branches that supply the parotid gland and duct, the masseter muscle, and the skin of the face.

• It anastomoses with branches of the facial artery.

->The two parietal bones (L. paries, wall) form large parts of the walls of the calvaria.
->On the outside of these smooth convex bones, there are slight elevations near the centre called parietal eminences.
->The middle of the lateral surfaces of the parietal bones is crossed by two curved lines, the superior and inferior temporal lines.
->The superior temporal line indicates an attachment of the temporal fascia; the inferior temporal line marks the superior limit of the temporalis muscle.
->The parietal bones articulate with each other in the median plane at the sagittal suture. The medial plane of the body passes through the sagittal suture.
->The inverted V-shaped suture between the parietal bones and the occipital bones is called the lambdoid suture because of its resemblance to the letter lambda in the Greek alphabet.
->The point where the parietal and occipital bones join is a useful reference point called the lambda. It can be felt as a depression in some people.
->In addition to articulation with each other and the frontal and occipital bones, the parietal bones articulate with the temporal bones and the greater wings of the sphenoid bone.
->In foetal and infant skulls, the bones of the calvaria are separated by dense connective tissue membranes at sutures.
->The large fibrous area where several sutures meet are called fonticuli or fontanelles.
->The softness of these bones and looseness of their connections at these sutures enable the calvaria to undergo changes of shape during birth called molding. Within a day or so after birth, the shape of the infant’s calvaria returns to normal.
->The loose construction of the new-born calvaria also allows the skull to enlarge and undergo remodelling during infancy and childhood.

->Relationships between the various bones are constantly changing during the active growth period.
->The increase in the size of the cranium is greatest during the first 2 years, the period of most rapid postnatal growth of the brain.
->The cranium normally increases in capacity until about 15 or 16 years of age; thereafter the cranium usually increases only slightly in size as its bones thicken for 3 to 4 years.

Eye 

At week 4, two depressions are evident on each of the forebrain hemispheres.  As the anterior neural fold closes, the optic pits elongate to form the optic vesicles.  The optic vesicles remain connected to the forebrain by optic stalks. 
The invagination of the optic vesicles forms a bilayered optic cup.  The bilayered cup becomes the dual layered retina (neural and pigmented layer)
Surface ectoderm forms the lens placode, which invaginates with the optic cup.
The optic stalk is deficient ventrally to contain choroids fissure to allow blood vessels into the eye (hyaloid artery).  The artery feeds the growing lens, but will its distal portion will eventually degenerate such that the adult lens receives no hyaloid vasculature.
At the 7th week, the choroids fissure closes and walls fuse as the retinal nerve get bigger.
The anterior rim of the optic vesicles forms the retina and iris.  The iris is an outgrowth of the distal edge of the retina.
Optic vesicles induces/maintains the development of the lens vesicle, which forms the definitive lens.  Following separation of the lens vesicle from the surface ectoderm, the cornea develops in the anterior 1/5th of the eye.
The lens and retina are surrounded by mesenchyme which forms a tough connective tissue, the sclera, that is continuous with the dura mater around the optic nerve.  
Iridopupillary membrane forms to separate the anterior and posterior chambers of the eye.  The membrane breaks down to allow for the pupil
Mesenchyme surrounding the forming eye forms musculature (ciliary muscles and pupillary muscles – from somitomeres 1 and 2; innervated by CN III), supportive connective tissue elements and vasculature.

Eyelids

Formed by an outgrowth of ectoderm that is fused at its midline in the 2nd trimester, but later reopen.

The Eye and Orbit

• The orbit (eye socket) appears as a bony recess in the skull when it is viewed from anteriorly.
• It almost surrounds the eye and their associated muscles, nerves and vessels, together with the lacrimal apparatus.

• The orbit is shaped somewhat like a four-side pyramid lying on its side, with its apex pointing posteriorly and its base anteriorly.