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Oral and Maxillofacial Surgery

Ludwig's Angina

Ludwig's angina is a serious, potentially life-threatening cellulitis or connective tissue infection of the submandibular space. It is characterized by bilateral swelling of the submandibular and sublingual areas, which can lead to airway obstruction. The condition is named after the German physician Wilhelm Friedrich Ludwig, who provided a classic description of the disease in the early 19th century.

Historical Background

  • Coining of the Term: The term "Ludwig's angina" was first coined by Camerer in 1837, who presented cases that included a classic description of the condition. The name honors W.F. Ludwig, who had described the features of the disease in the previous year.

  • Etymology:

    • The word "angina" is derived from the Latin word "angere," which means "to suffocate" or "to choke." This reflects the potential for airway compromise associated with the condition.
    • The name "Ludwig" recognizes the contributions of Wilhelm Friedrich Ludwig to the understanding of this medical entity.
  • Ludwig's Personal Connection: Interestingly, Ludwig himself died of throat inflammation in 1865, which underscores the severity of infections in the head and neck region.

Clinical Features

Ludwig's angina typically presents with the following features:

  1. Bilateral Swelling: The most characteristic sign is bilateral swelling of the submandibular area, which can extend to the sublingual space. This swelling may cause the floor of the mouth to elevate.

  2. Pain and Tenderness: Patients often experience pain and tenderness in the affected area, which may worsen with movement or swallowing.

  3. Dysphagia and Dysarthria: Difficulty swallowing (dysphagia) and changes in speech (dysarthria) may occur due to swelling and discomfort.

  4. Airway Compromise: As the swelling progresses, there is a risk of airway obstruction, which can be life-threatening. Patients may exhibit signs of respiratory distress.

  5. Systemic Symptoms: Fever, malaise, and other systemic signs of infection may be present.

Etiology

Ludwig's angina is most commonly caused by infections that originate from the teeth, particularly the second or third molars. The infection can spread from dental abscesses or periodontal disease into the submandibular space. The most common pathogens include:

  • Streptococcus species
  • Staphylococcus aureus
  • Anaerobic bacteria

Diagnosis and Management

  • Diagnosis: Diagnosis is primarily clinical, based on the characteristic signs and symptoms. Imaging studies, such as CT scans, may be used to assess the extent of the infection and to rule out other conditions.

  • Management:

    • Airway Management: Ensuring a patent airway is the top priority, especially if there are signs of respiratory distress.
    • Antibiotic Therapy: Broad-spectrum intravenous antibiotics are initiated to target the likely pathogens.
    • Surgical Intervention: In cases of significant swelling or abscess formation, surgical drainage may be necessary to relieve pressure and remove infected material.

Ridge Augmentation Procedures

Ridge augmentation procedures are surgical techniques used to increase the volume and density of the alveolar ridge in the maxilla and mandible. These procedures are often necessary to prepare the site for dental implants, especially in cases where there has been significant bone loss due to factors such as tooth extraction, periodontal disease, or trauma. Ridge augmentation can also be performed in conjunction with orthognathic surgery to enhance the overall facial structure and support dental rehabilitation.

Indications for Ridge Augmentation

  • Insufficient Bone Volume: To provide adequate support for dental implants.
  • Bone Resorption: Following tooth extraction or due to periodontal disease.
  • Facial Aesthetics: To improve the contour of the jaw and facial profile.
  • Orthognathic Surgery: To enhance the results of jaw repositioning procedures.

Types of Graft Materials Used

Ridge augmentation can be performed using various graft materials, which can be classified into the following categories:

  1. Autografts:

    • Bone harvested from the patient’s own body, typically from intraoral sites (e.g., chin, ramus) or extraoral sites (e.g., iliac crest).
    • Advantages: High biocompatibility, osteogenic potential, and lower risk of rejection or infection.
    • Disadvantages: Additional surgical site, potential for increased morbidity, and limited availability.
  2. Allografts:

    • Bone grafts obtained from a human donor (cadaveric bone) that have been processed and sterilized.
    • Advantages: No additional surgical site required, readily available, and can provide a scaffold for new bone growth.
    • Disadvantages: Risk of disease transmission and potential for immune response.
  3. Xenografts:

    •  Bone grafts derived from a different species, commonly bovine (cow) bone.
    • Advantages: Biocompatible and provides a scaffold for bone regeneration.
    • Disadvantages: Potential for immune response and slower resorption compared to autografts.
  4. Alloplasts:

    •  Synthetic materials used for bone augmentation, such as hydroxyapatite, calcium phosphate, or bioactive glass.
    • Advantages: No risk of disease transmission, customizable, and can be designed to promote bone growth.
    • Disadvantages: May not integrate as well as natural bone and can have variable resorption rates.

Surgical Techniques

  1. Bone Grafting:

    • The selected graft material is placed in the deficient area of the ridge to promote new bone formation. This can be done using various techniques, including:
      • Onlay Grafting: Graft material is placed on top of the existing ridge.
      • Inlay Grafting: Graft material is placed within the ridge.
  2. Guided Bone Regeneration (GBR):

    • A barrier membrane is placed over the graft material to prevent soft tissue infiltration and promote bone healing. This technique is often used in conjunction with grafting.
  3. Sinus Lift:

    • In the maxilla, a sinus lift procedure may be performed to augment the bone in the posterior maxilla by elevating the sinus membrane and placing graft material.
  4. Combination with Orthognathic Surgery:

    • Ridge augmentation can be performed simultaneously with orthognathic surgery to correct skeletal discrepancies and enhance the overall facial structure.

Management of Greenstick/Crack Fractures of the Mandible

Greenstick fractures (or crack fractures) are incomplete fractures that typically occur in children due to the flexibility of their bones. Fracture in mandible,  can often be managed conservatively, especially when there is no malocclusion (misalignment of the teeth).

Conservative Management

  • No Fixation Required:
    • For greenstick fractures without malocclusion, surgical fixation is generally not necessary.
    • Closed Reduction: The fracture can be managed through closed reduction, which involves realigning the fractured bone without surgical exposure.
  • Dietary Recommendations:
    • Patients are advised to consume soft foods and maintain adequate hydration with lots of fluids to facilitate healing and minimize discomfort during eating.

Surgical Management Options

In cases where surgical intervention is required, or for more complex fractures, the following methods can be employed:

  1. Kirschner Wire (K-wire) Fixation:

    • Indications: K-wires can be used for both dentulous (having teeth) and edentulous (without teeth) mandibles.
    • Technique: K-wires are inserted through the bone fragments to stabilize the fracture. This method provides internal fixation and helps maintain alignment during the healing process.
  2. Circumferential Wiring:

    • Indications: This technique is also applicable for both dentulous and edentulous mandibles.
    • Technique: Circumferential wiring involves wrapping wire around the mandible to stabilize the fracture. This method can provide additional support and is often used in conjunction with other fixation techniques.
  3. External Pin Fixation:

    • Indications: Primarily used for edentulous mandibles.
    • Technique: External pin fixation involves placing pins into the bone that are connected to an external frame. This method allows for stabilization of the mandible while avoiding intraoral fixation, which can be beneficial in certain clinical scenarios.

Mandibular Tori

Mandibular tori are bony growths that occur on the mandible, typically on the lingual aspect of the alveolar ridge. While they are often asymptomatic, there are specific indications for their removal, particularly when they interfere with oral function or prosthetic rehabilitation.

Indications for Removal

  1. Interference with Denture Construction:

    • Mandibular tori may obstruct the proper fitting of full or partial dentures, necessitating their removal to ensure adequate retention and comfort.
  2. Ulceration and Slow Healing:

    • If the mucosal covering over the torus ulcerates and the wound exhibits extremely slow healing, surgical intervention may be required to promote healing and prevent further complications.
  3. Interference with Speech and Deglutition:

    • Large tori that impede normal speech or swallowing may warrant removal to improve the patient's quality of life and functional abilities.

Surgical Technique

  1. Incision Placement:

    • The incision should be made on the crest of the ridge if the patient is edentulous (without teeth). This approach allows for better access to the torus while minimizing trauma to surrounding tissues.
    • If there are teeth present in the area, the incision should be made along the gingival margin. This helps to preserve the integrity of the gingival tissue and maintain aesthetics.
  2. Avoiding Direct Incision Over the Torus:

    • It is crucial not to make the incision directly over the torus. Incising over the torus can lead to:
      • Status Line: Leaving a visible line on the traumatized bone, which can affect aesthetics and function.
      • Thin Mucosa: The mucosa over the torus is generally very thin, and an incision through it can result in dehiscence (wound separation) and exposure of the underlying bone, complicating healing.
  3. Surgical Procedure:

    • After making the appropriate incision, the mucosal flap is elevated to expose the underlying bone.
    • The torus is then carefully removed using appropriate surgical instruments, ensuring minimal trauma to surrounding tissues.
    • Hemostasis is achieved, and the mucosal flap is repositioned and sutured back into place.
  4. Postoperative Care:

    • Patients may experience discomfort and swelling following the procedure, which can be managed with analgesics.
    • Instructions for oral hygiene and dietary modifications may be provided to promote healing and prevent complications.
  5. Follow-Up:

    • Regular follow-up appointments are necessary to monitor healing and assess for any potential complications, such as infection or delayed healing.

Alcohols as Antiseptics

Ethanol and isopropyl alcohol are commonly used as antiseptics in various healthcare settings. They possess antibacterial properties and are effective against a range of microorganisms, although they have limitations in their effectiveness against certain pathogens.

Mechanism of Action

  • Antibacterial Activity: Alcohols exhibit antibacterial activity against both gram-positive and gram-negative bacteria, including Mycobacterium tuberculosis.
  • Protein Denaturation: The primary mechanism by which alcohols exert their antimicrobial effects is through the denaturation of proteins. This disrupts cellular structures and functions, leading to cell death.

Effectiveness and Recommendations

  1. Contact Time:

    • According to Spaulding (1939), for alcohol to achieve maximum effectiveness, it must remain in contact with the microorganisms for at least 10 minutes. This extended contact time is crucial for ensuring adequate antimicrobial action.
  2. Concentration:

    • Solutions of 70% alcohol are more effective than higher concentrations (e.g., 90% or 100%). The presence of water in the 70% solution enhances the denaturation process of proteins, as reported by Lawrence and Block (1968). Water acts as a co-solvent, allowing for better penetration and interaction with microbial cells.

Management and Treatment of Le Fort Fractures

Le Fort fractures require careful assessment and management to restore facial anatomy, function, and aesthetics. The treatment approach may vary depending on the type and severity of the fracture.

Le Fort I Fracture

Initial Assessment:

  • Airway Management: Ensure the airway is patent, especially if there is significant swelling or potential for airway compromise.
  • Neurological Assessment: Evaluate for any signs of neurological injury.

Treatment:

  1. Non-Surgical Management:

    • Observation: In cases of non-displaced fractures, close monitoring may be sufficient.
    • Pain Management: Analgesics to manage pain.
  2. Surgical Management:

    • Open Reduction and Internal Fixation (ORIF): Indicated for displaced fractures to restore occlusion and facial symmetry.
    • Maxillomandibular Fixation (MMF): May be used temporarily to stabilize the fracture during healing.
  3. Postoperative Care:

    • Follow-Up: Regular follow-up to monitor healing and occlusion.
    • Oral Hygiene: Emphasize the importance of maintaining oral hygiene to prevent infection.

Le Fort II Fracture

Initial Assessment:

  • Airway Management: Critical due to potential airway compromise.
  • Neurological Assessment: Evaluate for any signs of neurological injury.

Treatment:

  1. Non-Surgical Management:

    • Observation: For non-displaced fractures, close monitoring may be sufficient.
    • Pain Management: Analgesics to manage pain.
  2. Surgical Management:

    • Open Reduction and Internal Fixation (ORIF): Required for displaced fractures to restore occlusion and facial symmetry.
    • Maxillomandibular Fixation (MMF): May be used to stabilize the fracture during healing.
  3. Postoperative Care:

    • Follow-Up: Regular follow-up to monitor healing and occlusion.
    • Oral Hygiene: Emphasize the importance of maintaining oral hygiene to prevent infection.

Le Fort III Fracture

Initial Assessment:

  • Airway Management: Critical due to potential airway compromise and significant facial swelling.
  • Neurological Assessment: Evaluate for any signs of neurological injury.

Treatment:

  1. Non-Surgical Management:

    • Observation: In cases of non-displaced fractures, close monitoring may be sufficient.
    • Pain Management: Analgesics to manage pain.
  2. Surgical Management:

    • Open Reduction and Internal Fixation (ORIF): Essential for restoring facial anatomy and occlusion. This may involve complex reconstruction of the midface.
    • Maxillomandibular Fixation (MMF): Often used to stabilize the fracture during healing.
    • Craniofacial Reconstruction: In cases of severe displacement or associated injuries, additional reconstructive procedures may be necessary.
  3. Postoperative Care:

    • Follow-Up: Regular follow-up to monitor healing, occlusion, and any complications.
    • Oral Hygiene: Emphasize the importance of maintaining oral hygiene to prevent infection.
    • Physical Therapy: May be necessary to restore function and mobility.

General Considerations for All Le Fort Fractures

  • Antibiotic Prophylaxis: Consideration for prophylactic antibiotics to prevent infection, especially in open fractures.
  • Nutritional Support: Ensure adequate nutrition, especially if oral intake is compromised.
  • Psychological Support: Address any psychological impact of facial injuries, especially in pediatric patients.

Maxillectomy

Maxillectomy is a surgical procedure involving the resection of the maxilla (upper jaw) and is typically performed to remove tumors, treat severe infections, or address other pathological conditions affecting the maxillary region. The procedure requires careful planning and execution to ensure adequate access, removal of the affected tissue, and preservation of surrounding structures for optimal functional and aesthetic outcomes.

Surgical Access and Incision

  1. Weber-Fergusson Incision:

    • The classic approach to access the maxilla is through the Weber-Fergusson incision. This incision provides good visibility and access to the maxillary region.
    • Temporary Tarsorrhaphy: The eyelids are temporarily closed using tarsorrhaphy sutures to protect the eye during the procedure.
  2. Tattooing for Aesthetic Alignment:

    • To achieve better cosmetic results, it is recommended to tattoo the vermilion border and other key points on both sides of the incision with methylene blue. These points serve as guides for alignment during closure.
  3. Incision Design:

    • The incision typically splits the midline of the upper lip but can be modified for better cosmetic outcomes by incising along the philtral ridges and offsetting the incision at the vermilion border.
    • The incision is turned 2 mm from the medial canthus of the eye. Intraorally, the incision continues through the gingival margin and connects with a horizontal incision at the depth of the labiobuccal vestibule, extending back to the maxillary tuberosity.
  4. Continuation of the Incision:

    • From the maxillary tuberosity, the incision turns medially across the posterior edge of the hard palate and then turns 90 degrees anteriorly, several millimeters to the proximal side of the midline, crossing the gingival margin again if possible.
  5. Incision to Bone:

    • The incision is carried down to the bone, except beneath the lower eyelid, where the orbicularis oculi muscle is preserved. The cheek flap is then reflected back to the tuberosity.

Surgical Procedure

  1. Extraction and Elevation:

    • The central incisor on the involved side is extracted, and the gingival and palatal mucosa are elevated back to the midline.
  2. Deepening the Incision:

    • The incision extending around the nose is deepened into the nasal cavity. The palatal bone is divided near the midline using a saw blade or bur.
  3. Separation of Bone:

    • The basal bone is separated from the frontal process of the maxilla using an osteotome. The orbicularis oculi muscle is retracted superiorly, and the bone cut is extended across the maxilla, just below the infraorbital rim, into the zygoma.
  4. Maxillary Sinus:

    • If the posterior wall of the maxillary sinus has not been invaded by the tumor, it is separated from the pterygoid plates using a pterygoid chisel.
  5. Specimen Removal:

    • The entire specimen is removed by severing the remaining attachments with large curved scissors placed behind the maxilla.

Postoperative Considerations

  • Wound Care: Proper care of the surgical site is essential to prevent infection and promote healing.
  • Rehabilitation: Patients may require rehabilitation to address functional issues related to speech, swallowing, and facial aesthetics.
  • Follow-Up: Regular follow-up appointments are necessary to monitor healing and assess for any complications or recurrence of disease.

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