Angle classified these relationships by using the first permanent molars

Normal or neutral occlusion (ideal):

Mesiobuccalgroove of the mandibular first molar align with the mesiobuccal cusp of the max laxy first permanent molar

ClassI  malocclusion  normal molar relationships with alterations to other characteristics of the occlusion such as versions, crossbites, excessive overjets, or overbites

Class II malocclusion a distal relation of the mesiobuccal groove of the mandibular first permanent molar to the mesiobuccal cusp of the maxillary first permanent molar

Division I: protruded maxillary anterior teeth

Division II: one or more maxillary anterior teeth retruded

Class III  malocclusion a mesial relation of the mesiobuccal groove of the mandibular first permanent molar to the mesiobuccal cusp of the maxillary molar

Permanent dentition period  

-Maxillary / mandibular occlusal relationships are established when the last of the deciduous teeth are lost. The adult relationship of the first permanent molars is established at this time.

-Occlusal and proximal wear reduces crown height to the permanent dentition and the mesiodistal dimensions of the teeth

occlusal and proximal wear also changes the anatomy of teeth. As cusps are worn off, the occlusion can become virtually flat plane. -In the absence of rapid wear, overbite and overjet tend to remain stable.

-Mesio-distal jaw relationships tend to be stable,

With aging, the teeth change in color from off white to yellow. smoking and diet can accelerate staining or darkening of the teeth.

Gingival recession results in the incidence of more root caries . With gingival recession, some patients have sensitivity due to exposed dentin at the cemento-enamel junction.

Curve of Spee.

-The cusp tips and incisal edges align so that there is a smooth, linear curve when viewed from the lateral aspect. The mandibular curve of Spee is concave whereas the maxillary curve is convex.

-It was described by Von Spee as a 4" cylinder that engages the occlusal surfaces.

-It is called a compensating curve of the dental arch.

There is another: the Curve of Wilson. Clinically, it relates to the anterior overbite: the deeper the curve, the deeper the overbite.

Mandibular First Deciduous Molar

-This tooth doesn't resemble any other tooth. It is unique unto itself.

-There are two roots.

-There is a strong bulbous enamel bulge buccally at the mesial.

- the mesiolingual cusps on this tooth is the highest and largest of the cusps.

Types of dentitions:

1. Diphyodont. Teeth develop and erupt into their jaws in two generations of teeth. The term literally means two generations of teeth.

2. Monophyodont. a single generation of teeth.

3. Polyphyodont. Teeth develop a lifetime of generations of successional teeth

4. Homodont. all of the teeth in the jaw are alike. They differ from each other only in size.

5. Heterodont. There is distinctive classes of teeth that are regionally specialized.

Amelogenesis and Enamel

Enamel is highly mineralized: 85% hydroxyapatite crystals
Enamel formation is a two-step process
The first step produces partially mineralized enamel: 30% (secretory)
The second step: Influx of minerals, removal of water and organic matrix (maturative)
Again, dentin is the prerequisite of enamel formation (reciprocal induction)
Stratum intermedium: high alkaline phosphatase activity
Differentiation of ameloblasts: Increase in glycogen contents

Formation of the enamel matrix
Enamel proteins, enzymes, metalloproteinases, phosphatases, etc.
Enamel proteins: amelogenins (90%), enamelin, tuftelin, and amelin
Amelogenins: bulk of organic matrix
Tuftelin: secreted at the early stages of amelogenesis (area of the DE junction)
Enamelin: binds to mineral
Amelin

Mineralization of enamel
 No matrix vesicles
Immediate formation of crystallites
Intermingling of enamel crystallites with dentin
"Soft" enamel is formed

Histologic changes

Differentiation of inner enamel epithelium cells. They become ameloblasts
Tomes' processes: saw-toothed appearance
Collapse of dental organ
Formation of the reduced enamel epithelium

Hard tissue formation (Amelogenesis )

Enamel formation is called amelogenesis and occurs in the crown stage of tooth development. "Reciprocal induction" governs the relationship between the formation of dentin and enamel; dentin formation must always occur before enamel formation. Generally, enamel formation occurs in two stages: the secretory and maturation stages. Proteins and an organic matrix form a partially mineralized enamel in the secretory stage; the maturation stage completes enamel mineralization.

In the secretory stage, ameloblasts release enamel proteins that contribute to the enamel matrix, which is then partially mineralized by the enzyme alkaline phosphatase. The appearance of this mineralized tissue, which occurs usually around the third or fourth month of pregnancy, marks the first appearance of enamel in the body. Ameloblasts deposit enamel at the location of what become cusps of teeth alongside dentin. Enamel formation then continues outward, away from the center of the tooth.

In the maturation stage, the ameloblasts transport some of the substances used in enamel formation out of the enamel. Thus, the function of ameloblasts changes from enamel production, as occurs in the secretory stage, to transportation of substances. Most of the materials transported by ameloblasts in this stage are proteins used to complete mineralization. The important proteins involved are amelogenins, ameloblastins, enamelins, and tuftelins. By the end of this stage, the enamel has completed its mineralization.