NEET MDS Lessons
Anatomy
Cardiac Muscle
Fibres anastomose through cross bridges
Fibres are short, connected end to end at intercalated discs, also striated, contract automatically
Light microscopic Structure:
Short fibres connected at intercalated disks, 85 - 100 µm long, 15 µm
same bands as in skeletal muscle, 1 or 2 nuclei - oval and central, in perinuclear area is a sarcoplasmic reticulum, intercalated discs lie at the Z line
Electron microscopic structure:
Between myofibrils lie the mitochondria, 2,5 µm long mitochondria, dense cristae
and are as long as the sarcomere, fibres have more glycogen than skeletal muscle fibres
myofilaments, actin and myosin are the same as in skeletal muscle, the sarcoplasmic reticulum differs in that there is no terminal sisterna. The sarcotubules end in little feet that
sit on the T-tubule
Intercalated Disc:
on Z lines, fibres interdigitate,
3 types of junctions in the disc
Transverse Part:
zonula adherens
desmosomes
Lateral Part:
Gap junctions (nexus) - for impulse transfer
Mechanism of Contraction:
slide - ratchet like in skeletal muscle, certain fibres are modified for conduction, Impulses spread from cell to cell through gap junctions, Purkinje cells are found in the AV bundle
they have less myofibrils, lots of glycogen and intercalated discs
Connective tissue coverings:
Only endomycium in cardiac muscle, Blood vessels, lymph vessels and nerves lie in the endomycium
Histology
Histology is the study of tissues.
A tissue is a group of cells with similar structure and function plus the extracellular substances located between the cells.
There are four basic types of tissues:
- Epitheliums
- Connective tissue
- Muscle tissue
- Nervous tissue
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Articulations
Classified according to their structure, composition,and movability
• Fibrous joints-surfaces of bones almost in direct contact with limited movement
o Syndesmosis-two bones united by interosseous ligaments
o Sutures-serrated margins of bones united by a thin layer of fibrous tissue
o Gomphosis-insertion of a cone-shaped process into a socket• Cartilaginous joints-no joint cavity and contiguous bones united by cartilage
o Synchondrosis-ends of two bones approximated by hyaline cartilage
o Symphyses-approximating bone surfaces connected by fibrocartilage• Synovial joints-approximating bone surfaces covered with cartilage; may be separated by a disk; attached by ligaments
o Hinge-permits motion in one plane only
o Pivot-permits rotary movement in which a ring rotates around a central axis
o Saddle-opposing surfaces are convexconcave. allowing great freedom of motion
o Ball and socket - capable of movement in an infinite number of axes; rounded head of one bone moves in a cuplike cavity of the approximating boneBursae
• Sacs filled with synovial fluid that are present where tendons rub against bone or where skjn rubs across bone
• Some bursae communicate with a joint cavity
• Prominent bursae found at the elbow. hip, and knee'Movements
• Gliding
o Simplest kind of motion in a joint
o Movement on a joint that does not involve any angular or rotary motions
• Flexion-decreases the angle formed by the union of two bones
• Extension-increases the angle formed by the union of two bones
• Abduction-occurs by moving part of the appendicular skeleton away from the median plane of the body
• Adduction-occurs by moving part of the appendicular skeleton toward the median plane of the body
• Circumduction
o Occurs in ball-and-socket joints
o Circumscribes the conic space of one bone by the other bone
• Rotation-turning on an axis without being displaced from that axis
- This is the second cranial nerve (CN II) and is the nerve of sight.
Intrinsic muscles
all innervated by recurrent laryngeal nerve except cricothyroid: external laryngeal nerve
adductors of vocal folds: bring folds together at midline
Transverse and oblique arytenoids: pull arytenoids together
Lateral cricoartenoids: spin and slide arytenoids up
only one abductor of vocal folds
Posterior cricoarytenoids—down and up
adjustors of shape and tension of vocal folds
Cricothyroid muscle
o superficial to lateral cricoarytenoid
o tenses vocal folds by tilting thyroid cartilage forward and sliding forward
Thyroartenoid and vocalis muscles
o vocalis: sometimes treated as medial most fibers of thyroartenoid muscle
o different fiber directions
lateral: adduct
medial: change shape of folds
control voice by bring bringing together different parts of folds
o as move from epithelium to vocalis muscle, fold becomes stiffer
o near connections, vocal folds are stiffer
o vocal fold: complex, multilayered vibrator
Muscles of the Soft Palate
The Levator Veli Palatini (Levator Palati)
- Superior attachment: cartilage of the auditory tube and petrous part of temporal bone.
- Inferior attachment: palatine aponeurosis.
- Innervation: pharyngeal branch of vagus via pharyngeal plexus.
- This cylindrical muscle runs inferoanteriorly, spreading out in the soft palate, where it attaches to the superior surface of the palatine aponeurosis.
- It elevates the soft palate, drawing it superiorly and posteriorly.
- It also opens the auditory tube to equalise air pressure in the middle ear and pharynx.
The Tensor Veli Palatini (Tensor Palati)
- Superior attachment: scaphoid fossa of medial pterygoid plate, spine of sphenoid bone, and cartilage of auditory tube.
- Inferior attachment: palatine aponeurosis.
- Innervation: medial pterygoid nerve (a branch of the mandibular nerve).
- This thin, triangular muscle passes inferiorly, and hooks around the hamulus of the medial pterygoid plate.
- It then inserts into the palatine aponeurosis.
- This muscle tenses the soft palate by using the hamulus as a pulley.
- It also pulls the membranous portion of the auditory tube open to equalise air pressure of the middle ear and pharynx.
The Palatoglossus Muscle
- Superior attachment: palatine aponeurosis.
- Inferior attachment: side of tongue.
- Innervation: cranial part of accessory nerve (CN XI) through the pharyngeal branch of vagus (CN X) via the pharyngeal plexus.
- This muscle, covered by mucous membrane, forms the palatoglossal arch.
- The palatoglossus elevates the posterior part of the tongue and draws the soft palate inferiorly onto the tongue.
- Superior attachment: hard palatThe Palatopharyngeus Musclee and palatine aponeurosis.
- Inferior attachment: lateral wall of pharynx.
- Innervation: cranial part of accessory nerve (CN XI) through the pharyngeal branch of vagus (CN X) via the pharyngeal plexus.
- This thin, flat muscle is covered with mucous membrane to form the palatopharyngeal arch.
- It passes posteroinferiorly in this arch.
- This muscle tenses the soft palate and pulls the walls of the pharynx superiorly, anteriorly and medially during swallowing.
The Musculus Uvulae
- Superior attachment: posterior nasal spine and palatine aponeurosis.
- Inferior attachment: mucosa of uvula.
- Innervation: cranial part of accessory through the pharyngeal branch of vagus, via the pharyngeal plexus.
- It passes posteriorly on each side of the median plane and inserts into the mucosa of the uvula.
- When the muscle contracts, it shortens the uvula and pulls it superiorly.
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Ossification
- Intramembranous-found in the flat bones of the face
- Mesenchymal cells cluster and form strands
- Strands are cemented in a uniform network. Which is known as osteoid
- Calcium salts are deposited; osteoid is converted to bone
- Trabeculae are formed and make cancellous bone with open spaces known as marrow cavities
- Periosteum forms on the inner and outer surfaces of the ossification centers
- Surface bone becomes compact bone
- Endochondral-primary type of ossification In the human