Innervation of the Skin

• Innervation of the skin is mainly through the three branches of the trigeminal nerve (CN V).
• Some skin over the angle of the mandible and anterior and posterior of the auricle is supplied by the great auricular nerve from the cervical plexus.
• Some cutaneous branches of the auricular branch of the facial nerve also supplies skin on both sides of the auricle.

• The trigeminal nerve is the general sensory nerve to the head, particularly the face, and is the motor nerve to the muscles of mastication.

The Ophthalmic Nerve

• This is the superior division of the trigeminal nerve, the smallest of the three branches and is wholly sensory.
• The ophthalmic nerve divides into three branches: the nasociliary, frontal and lacrimal just before entering the orbit through the superior orbital fissure.

• The nasociliary nerve supplies the tip of the nose through the external nasal branch of the anterior ethmoidal nerve.

• The frontal nerve is the direct continuation of CN V¹ and divides into two branches, the supraorbital and supratrochlear.
• The supratrochlear nerve supplies the middle part of the forehead.
• The supraorbital nerve supplies the lateral part and the front of the scalp.

• The lacrimal nerve, the smallest of the main ophthalmic branches, emerges over the superolateral orbital margin to supply the lacrimal gland and the lateral part of the upper eyelid.

The Maxillary Nerve

• This is the intermediate division of the trigeminal nerve.
• It has three cutaneous branches.

• The infraorbital nerve is the largest terminal branch of the maxillary nerve.
• It passes through the infraorbital foramen and breaks up into branches that supplies the skin on the lateral aspect of the nose, upper lip and lower eyelid.

• The zygomaticofacial nerve, a small branch of the maxillary, emerges from the zygomatic bone from a foramen with the same name.
• It supplies the skin over the zygomatic bone.

• The zygomaticotemporal nerve emerges from the zygomatic bone from foramen of the same name.
• It supplies the skin over the temporal region.

The Mandibular Nerve

• This is the inferior division of the trigeminal nerve.
• Of the three division of the trigeminal nerve, CN V³ is the only one that carries motor fibres (to the muscles of mastication).
• The main sensory branches of the mandibular nerve are the buccal, auriculotemporal, inferior alveolar and lingual nerves.

• The buccal nerve is a small branch of the mandibular that emerges from deep to the ramus of the mandible.
• It supplies the skin of the cheek over the buccinator muscle, the mucous membrane lining the cheek, and the buccal surface of the gingiva.

• The auriculotemporal nerve passes medially to the neck of the mandible and then turns superiorly, posterior to its head and anterior to the auricle. It then crosses over the root of the zygomatic process of the temporal bone, deep to the superficial temporal artery.

• It supplies the auricle, external acoustic meatus, tympanic membrane, and the skin in the temporal region.

• The inferior alveolar nerve is the large terminal branch of the posterior division of the mandibular nerve (the lingual nerve is the other terminal branch).
• It enters the mandible through the mandibular foramen to the mandibular canal. In the canal, it gives branches to the mandibular teeth.
• Opposite the mental foramen, this nerve divides into the mental nerve and the incisive nerve.
• The incisive nerve supplies the incisor teeth, the adjacent gingiva and the mucosa of the lower lip.
• The mental nerve emerges from the mental foramen and supplies the skin of the chin and the skin and mucous membrane of the lower lip and gingiva.

• The lingual nerve is the smaller terminal branch of the mandibular nerve.
• It supplies the general sensory fibres to the anterior two-thirds of the tongue, the floor of the mouth and the gingivae of the mandibular teeth.

Smooth Muscle

Light microscopic Structure:

cells - long - spindle shaped,  nucleus lies in the widest widest part of the fiber,  when the fiber contract the nucleus become folded, 30 - 200 µm long,between fibres lie endomycium

Electron microscopic structure:

 Mitochondria, ribosomes, golgi, rough EPR, myofilaments are present but no sarcomeres and no Z lines,thin filaments - actin and tropomyosin (7nm), thick filaments - myosin (17nmØ)

- intermediate filaments (10 nm)

- actin and myosin overlap more than in skeletal muscle and can therefore contract more

 A rudimentary sacroplasmic reticulum is present in the form of invaginations on the surface called caveolae , So there are no T-tubules,  Cells communicate through gap junctions.

Dense bodies

Filaments are attached to dense bodies which take the place of the Z line in skeletal muscle

There are two types of dense bodies - cytoplasmic and membrane

contains a percentage actinin (like the Z line)

dense bodies transmit contractile force to adjacent fibres

Arrangement:

Fibres can be single or in groups, normally arranged in sheaths,  In the GIT are 2 or 3 layers

Nerve supply:

2 types:

Where it is arranged in layers a few fibres are innervated together

impulse spread through the gap junctions between fibres (slow contraction)

In the iris and the vas deferens each fiber is individually supplied (quick contraction)

Appendicular Skeleton
Upper extremity
•    Shoulder-clavicle and scapula

Clavicle
    Articulates with the manubrium at the sternal end
    Articulates with the scapula at the lateral end
    Slender S-shaped bone that extends horizontally across the upper part of the thorax
    
Scapula

    Triangular bone with the base upward and the apex downward
    Lateral aspect contains the glenoid cavity that articulates with the head of the humerus
    Spine extends across the upper part of the posterior surface; expands laterally and
    forms the acromion (forms point of shoulder) 
    Coracoid process projects anteriorly from the upper part of the neck of the scapula
    
Arm (humerus)

Consists of a shaft (diaphysis) and two ends (epiphyses)
Proximal end has a head that articulates with the glenoid fossa of the scapula
Greater and lesser tubercles lie below the head

Intertubercular groove is located between them; long tendon of the biceps attaches here
Surgical neck is located below the tubercles

    o    Radial groove runs obliquely on the posterior surface; radial nerve is located here

    o    Deltoid muscles attaches in a V-shaped area in the middle of the shaft. called the deltoid tuberosity
    
Distal end has two projections. the medial and lateral epicondyles
Capitulum-articulates with the radius
Trochlea-articulates with the ulqa

Forearm

Radius
Lateral bone of the forearm
Radial tuberosity is located below the head on the medial side
Distal end is broad for articulation with the wrist: has a styloid process on its lateral side

Ulna

    Medial side of the forearm
    Conspicuous part of the elbow joint (olecranon)
    Curved surface that articulates with the trochlea of the humerus is the trochlearnotch
    Lateral ide is concave (radial notch); articulates with the head of the radius Distal end contains the styloid process 
    Distal end contains the styloid process

Hand

Carpal bones (8)
    Aranged in two rows of four
    Scaphoid. lunate. triquetral. and pisiform  proximal row); trapezium. trapezoid.
    capitate. and hamate (distal row)
    
Metacarpal bones (5)
    Framework of the hand
    Numbered 1 to 5 beginning on the lateral side
    
Phalanges (14)
    Fingers
     Three phalanges in each finger; two phalanges in the thumb

• Skull 
  Cranium
  o    Superior portion formed by the frontal. parietal, and occipital bones
  o    Lateral portions formed by the temporal and sphenoid bones
  o    Cranial base formed by the temporal. sphenoid, and ethmoid bones
  o    Fontanels-soft spots in which ossification is incomplete at birth

  Frontal bone
  o    Forms the forehead
  o    Contains the frontal sinuses
  o    Forms the roof of the orbits
  o    Union with the parietal bones forms the coronal suture

  Parietal bones
  o    Union with the occipital bone forms the lambdoid suture
  o    Union with the temporal bone forms the squamous suture
  o    Union with the sphenoid bone forms the coronal suture

  Temporal bones
  o    Contains the external auditory meatus and middle and inner ear structures
  o    Squamous portion-above the meatus: zygomatic process-articulates with the zygoma
  o    to form the zygomatic arch 

  •    Petrous portion
  o    Contains organs of hearing and equilibrium 
  o    Prominent elevation on the floor of the cranium

  •    Mastoid portion
  o    Protuberance behind the ear

  o    Mastoid process
  •    Glenoid fossa-articulates with the condyle on the mandible
  •    Styloid process-anterior to the mastoid process; several neck muscles attach here
  •    Stylomastoid foramen-located between the styloid and mastoid processes; facial nerve emerges through this opening
  •    Jugular foramen-located between the petrous portion and the occipital bone: cranial nerves IX. X, and XI exit
   

The Meatus of the Nose

Sphenopalatine Recess

• This space is posterosuperior to the superior concha.
• The sphenoidal sinus opens into this recess.

Superior Meatus

• This is a narrow passageway between the superior and middle nasal conchae.
• The posterior ethmoidal sinuses open into it by one or more orifices.

Middle Meatus

• This is longer and wider than the superior one.

• The anterosuperior part of this meatus lead into a funnel-shaped opening, called the infundibulum, through which the frontonasal duct leads to the frontal sinus.
• There is one duct for each frontal sinus and since there may be several, there may be several frontonasal ducts.

• When the middle concha is removed, rounded elevation called the ethmoidal bulla (L. bubble), is visible
• The middle ethmoidal air cells open on the surface of the ethmoidal bulla.

• Inferior to this bulla is a semicircular groove called the hiatus semilunaris.
• The frontal sinus opens into this hiatus anterosuperiorly.
• Near the hiatus are the openings of the anterior ethmoid air cells.
• The maxillary sinus also opens into the middle meatus.

Inferior Meatus

• This is a horizontal passage, inferolateral to the inferior nasal concha.
• The nasolacrimal duct opens into the anterior part of this meatus.
• Usually, the orifice of this duct is wide and circular.

Hip

Constitutes the pelvic girdle
United with the vertebral column
Union of three parts that is marked by a cup shaped cavity (acetabulum) Ilium
•    Prominence of the hip
•    Superior border is the crest
•    Anterosuperior spine-projection at the anterior tip of the crest
•    Corresponding projections on the posterior part are the posterosuperior and posteroinferior iliac spines
•    Greater sciatic notch-located beneath the posterior part
•    Most is a smooth concavity (iliac fossa)
•    Posteriorly it is rough and articulates with the sacrum in the formation of the sacroiliac joint

Pubic bone

Anterior part of the innominate bone
Symphysis pubic-joining of the two pubic bones at the midline
Body and two rami 
•    Body forms one fifth of the acetabulum
•    Superior ramis extends from the body to the median plane: superior border forms the pubic crest
•    Inferior ramus extends downward and meets with the ischium
•    Pubic arch is formed by the inferior rami of both pubic hones

Ischium
    Forms the lower and back part of the innominate bone
    Body
•    Forms two fifths of the accrabulum
•    Ischial tuberosiry-supports the body in a sitting position
•    Ramus-passes upward to join the inferior ramus of rhe pubis; known as rhe obturator foramen

Pelvis

Fanned by the right and left hip bones, sacrum, and coccyx

Greater pelvis

o    Bounded by the ilia and lower lumbar vertebrae
o    Gives support to the abdominal viscera

Lesser pelvis

o    Brim of the pelvis corresponds to the sacral promontory
o    Inferior outlet is bounded by the tip of the coccyx, ischial tuberosities, and inferior rami of the pubic bones

Female pelvis

o    Shows adaptations related to functions as a birth canal Wide outlet
o    Angle of the pubic arch is obtuse

Male pelvis

o    Shows adaptations that contribute to power and speed
o    Heart-shaped outlet
o    Angle of the pubic arch is acute

Thigh

Femur-longest and strongest bone of the body
Proximal end has a rounded head that articulates with the acetabulum
Constricted portion-the neck
Greater and lesser trochanters
Slightly arched shaft; is concave posteriorly
o    Linea aspera-strengthened by this prominent ridge
o    Site of attachment for several muscles
Distal end has two condyles separated on the posterior side by the intercondyloid notch

Knee cap

Patella-sesamoid bone
Embedded in the tendon of the quadriceps muscle
Articulates with the femur

Leg

Tibia-medial bone
o    Proximal end has two condyles that articulate with the femur
o    Triangular shaft

    Anterior-shin
    Posterior-soleal line
    Distal-medial malleolus that articulates with the latus to form the ankle joint
Fibula-lateral bone
o    Articulates with the lateral condyle of the tibia but does not enter the knee joint
o    Distal end projects as the lateral malleolus

Ankle, foot, and toes

Adapted for supporting weight but similar in structure to the hand

Talus

o    Occupies the uppennost and central position in the tarsus
o    Distributes the body weight from the tibia above to the other tarsal bones
Calcaneus (heel)-Iocated beneath the talus
Navicular-located in front of the talus on the medial side; articulates with three cuneifonn bones distally
Cuboid-lies along the lateral border of the navicular bone

Metatarsals
o    First, second, and third p1etatarsals lie in front of the three cuneifonn bones
o    (2) Fourth and fifth metatarsals lie in front of the cuboid bone

Phalanges

o    Distal to the metatarsals
o    (2) Two in the great toe; three in each of the other four toes .

Longitudinal arches in the foot (2)

o    Lateral-fonned by the calcaneus, talus, cuboid, and fourth and fifth metatarsal bones
o    Medial-fonned by the calcaneus, talus, navicular, cuneifonn, and first, second, and third metatarsal bones

Transverse arches-formed by the tarsal and metatarsal bones