Histology

Histology is the study of tissues.

A tissue is a group of cells with similar structure and function plus the extracellular substances located between the cells.

There are four basic types of tissues:

- Epitheliums

- Connective tissue

- Muscle tissue

- Nervous tissue

A. Anatomic position-erect body position with the arms at the sides and the palms  upward

B. Plane or section

1. Definition-imaginary flat surface formed by an extension through an axis

2. Median plane-a vertical plane. that divides a body into right and left halves

3. Sagittal plane

• Any plane parallel to the median plane
• Divides the body into right and left portions

4. Frontal plane

• Vertical plane that forms at right angles to the sagittal plane
• Divides the body into anterior and posterior sections
• Synonymous with the term coronal plane

5. Transverse plane

• Horizontal plane that forms at right angles to the sagittal and frontal planes
• Divides the body into upper and lower portions
• Synonymous with the term horizontal plane

C. Relative positions

1. Anterior

• Nearest the abdominal surface and the front of the body
• Synonymous with the term ventral
• In referring to hands and forearms, the terms palmar and Volar are used

2. Posterior

• Back of the body
• Synonymous with the term dorsal

3. Superior

• Upper or higher
• Synonymous with the term cranial (head)

4. Inferior

• Below or lower
• Synonymous with the term caudal (tail)
• In referring to the top of the foot and the sole of the foot. the terms dorsal and plantar are used respectively

5. Medial-near to the median plane

6. Lateral-farther away from the median plane

7. Proximal-near the source or attachment

8. Distal-away from the source or. attachment

9. Superficial-near the surface

10. Deep-away from the surface

11. Afferent-conducting toward a structure

12. Efferent-conducting away from a structure

The External Ear

• The auricle (L. auris, ear) is the visible, shell-like part of the external ear.
• It consists of a single elastic cartilage that is covered on both surfaces with thin, hairy skin.
• The external ear contains hairs, sweat glands, and sebaceous glands.
• The cartilage is irregularly ridged and hollowed, which gives the auricle its shell-like form.
• It also shapes the orifice of the external acoustic meatus.

The Ear Lobule

• The ear lobule (earlobe) consists of fibrous tissue, fat and blood vessels that are covered with skin.
• The arteries are derived mainly from the posterior auricular artery and the superficial temporal artery.
• The skin of the auricle is supplied by the great auricular and auriculotemporal nerves.

• The great auricular nerve supplies the superior surface and the lateral surface inferior to the external acoustic meatus with nerve fibres from C2.
• The auriculotemporal nerve supplies the skin of the auricle superior to the external acoustic meatus.

The External Acoustic Meatus

• This passage extends from the concha (L. shell) of the auricle to the tympanic membrane (L. tympanum, tambourine). It is about 2.5 cm long in adults.
• The lateral 1/3 of the S-shaped canal is cartilaginous, whereas its medial 2/3 is bony.

• The lateral third of the meatus is lined with the skin of the auricle and contains hair follicles, sebaceous glands, and ceruminous glands.
• The latter glands produce cerumen (L. cera, wax).

• The medial two-thirds of the meatus is lined with very thin skin that is continuous with the external layer of the tympanic membrane.

• The lateral end of the meatus is the widest part. It has the diameter about that of a pencil.
• The meatus becomes narrow at its medial end, about 4 mm from the tympanic membrane.
• The constricted bony part is called the isthmus.

• Innervation of the external acoustic meatus is derived from three cranial nerves:

1. The auricular branch of the auriculotemporal nerve (derived from the mandibular, CN V³).
2. The facial nerve (CN VII) by the branches from the tympanic plexus.
3. The auricular branch of the vagus nerve (CN X).

The Tympanic Membrane

• This is a thin, semi-transparent, oval membrane at the medial end of the external acoustic meatus.
• It forms a partition between the external and middle ears.
• The tympanic membrane is a thin fibrous membrane, that is covered with very thin skin externally and mucous membrane internally.

• The tympanic membrane shows a concavity toward the meatus with a central depression, the umbo, which is formed by the end of the handle of the malleus.
• From the umbo, a bright area referred to as the cone of light, radiates anteroinferiorly.

• The external surface of the tympanic membrane is supplied by the auriculotemporal nerve.
• Some innervation is supplied by a small auricular branch of the vagus nerve (CN X); this nerve may also contain some glossopharyngeal and facial nerve fibres.

Walls of the Tympanic Cavity or Middle Ear

• This cavity is shaped like a narrow six-sided box that has convex medial and lateral walls.
• It has the shape of the biconcave lens in cross-section (like a red blood cell).

The Roof or Tegmental Wall

• This is formed by a thin plate of bone, called the tegmen tympani (L. tegmen, roof).
• It separates the tympanic cavity from the dura on the floor of middle cranial fossa.
• The tegmen tympani also covers the aditus ad antrum.

The Floor or Jugular Wall

• This wall is thicker than the roof.
• It separates the tympanic cavity from the superior bulb of the internal jugular vein. The internal jugular vein and the internal carotid artery diverge at the floor of the tympanic cavity.

• The tympanic nerve, a branch of the glossopharyngeal nerve (CN IX), passes through an aperture in the floor of the tympanic cavity and its branches form the tympanic plexus.

The Lateral or Membranous Wall

• This is formed almost entirely by the tympanic membrane.
• Superiorly it is formed by the lateral bony wall of the epitympanic recess.
• The handle of the malleus is incorporated in the tympanic membrane, and its head extends into the epitympanic recess.

The Medial or Labyrinthine Wall

• This separates the middle ear from the membranous labyrinth (semicircular ducts and cochlear duct) encased in the bony labyrinth.
• The medial wall of the tympanic cavity exhibits several important features.

• Centrally, opposite the tympanic membrane, there is a rounded promontory (L. eminence) formed by the first turn of the cochlea.
• The tympanic plexus of nerves, lying on the promontory, is formed by fibres of the facial and glossopharyngeal nerves.

• The medial wall of the tympanic cavity also has two small apertures or windows.

• The fenestra vestibuli (oval window) is closed by the base of the stapes, which is bound to its margins by an annular ligament.
• Through this window, vibrations of the stapes are transmitted to the perilymph window within the bony labyrinth of the inner ear.

• The fenestra cochleae (round window) is inferior to the fenestra vestibuli.
• This is closed by a second tympanic membrane.

The Posterior or Mastoid Wall

• This wall has several openings in it.
• In its superior part is the aditus ad antrum (mastoid antrum), which leads posteriorly from the epitympanic recess to the mastoid cells.

• Inferiorly is a pinpoint aperture on the apex of a tiny, hollow projection of bone, called the pyramidal eminence (pyramid).
• This eminence contains the stapedius muscle.
• Its aperture transmits the tendon of the stapedius, which enters the tympanic cavity and inserts into the stapes.

• Lateral to the pyramid, there is an aperture through which the chorda tympani nerve, a branch of the facial nerve (CN VII), enters the tympanic cavity.

The Anterior Wall or Carotid Wall

• This wall is a narrow as the medial and lateral walls converge anteriorly.
• There are two openings in the anterior wall.

• The superior opening communicates with a canal occupied by the tensor tympani muscle.
• Its tendon inserts into the handle of the malleus and keeps the tympanic membrane tense.

• Inferiorly, the tympanic cavity communicates with the nasopharynx through the auditory tube.

The Nasal Mucosa

• Mucosa lines the entire nasal cavities except for the vestibule of the nose.
• The nasal mucosa is firmly bound to the periosteum and perichondrium of the supporting structures of the nose.
• It is continuous with the adjoining cavities to which the nasal cavity communicates (e.g., the nasopharynx and paranasal sinuses).

• The inferior 2/3 of the nasal mucosa is called the respiratory area and air passing over this is warmed and moistened before it passes into the lungs.
• The superior 1/3 is called the olfactory area.

The Olfactory Area of Nasal Mucosa

• This area contains the peripheral organ of smell.
• Sniffing draws air into this area
• Olfactory receptor cells (from the olfactory nerve, CN I, are located in the mucosa of this area in the nose.

Nerves to the Respiratory Area of Nasal Mucosa

• The inferior 2/3 of the nasal mucosa are supplied chiefly by the trigeminal nerve (CN V).

• The mucous membrane of the nasal septum is supplied chiefly by the nasopalatine nerve, a branch of the maxillary nerve (CN V²).
• Its anterior portion is supplied by the anterior ethmoidal nerve (a branch of the nasociliary nerve) which is derived from the ophthalmic nerve (CN V¹).

• The lateral walls of the nasal cavity are supplied by branches of the maxillary nerve (CN V²); the greater palatine nerve, and the anterior ethmoidal nerve.

Arteries of the Nasal Mucosa

• The blood supply of the mucosa of the nasal septum is derived mainly from the maxillary artery.

• The sphenopalatine artery, a branch of the maxillary, supplies most of the blood of the nasal mucosa.
• It enters by the sphenopalatine foramen and sends branches to the posterior regions of the lateral wall and to the nasal septum.

• The greater palatine artery, also a branch of the maxillary, passes through the incisive foramen to supply the nasal septum.

• The anterior and posterior ethmoidal arteries, branches of the ophthalmic artery, supply the anterosuperior part of the mucosa of the lateral wall of the nasal cavity and nasal septum.

• Three branches of the facial artery (superior labial, ascending palatine, and lateral nasal) also supply the anterior parts of the nasal mucosa.

Veins of the Nasal Mucosa

• The veins of the nasal mucosa form a venous network of plexus in the connective tissue of the nasal mucosa.
• Some of the veins open into the sphenopalatine vein and drain to the pterygoid plexus.
• Others join the facial and infraorbital veins.
• Some empty into the ophthalmic veins and drain into the cavernous sinus.