Muscles Moving the Auditory Ossicles

The Tensor Tympani Muscle

• This muscle is about 2 cm long.

• Origin: superior surface of the cartilaginous part of the auditory tube, the greater wing of the sphenoid bone, and the petrous part of the temporal bone.
• Insertion: handle of the malleus.
• Innervation: mandibular nerve (CN V³) through the nerve to medial pterygoid.

• The tensor tympani muscle pulls the handle of the malleus medially, tensing the tympanic membrane, and reducing the amplitude of its oscillations.
• This tends to prevent damage to the internal ear when one is exposed to load sounds.

The Stapedius Muscle

• This tiny muscle is in the pyramidal eminence or the pyramid.

• Origin: pyramidal eminence on the posterior wall of the tympanic cavity. Its tendon enters the tympanic cavity by traversing a pinpoint foramen in the apex of the pyramid.
• Insertion: neck of the stapes.
• Innervation: nerve to the stapedius muscle, which arises from the facial nerve (CN VII).

• The stapedius muscle pulls the stapes posteriorly and tilts its base in the fenestra vestibuli or oval window, thereby tightening the anular ligament and reducing the oscillatory range.
• It also prevents excessive movement of the stapes.

The Medial Wall of the Orbit 

• This wall is paper-thin and is formed by the orbital lamina or lamina papyracea of the ethmoid bone, along with contributions from the frontal, lacrimal, and sphenoid bones (L. papyraceus, "made of papyrus" or parchment paper).

• There is a vertical lacrimal groove in the medial wall, which is formed anteriorly by the maxilla and posteriorly by the lacrimal bone.
• It forms a fossa for the lacrimal sac and the adjacent part of the nasolacrimal duct.

• Along the suture between the ethmoid and frontal bones are two small foramina; the anterior and posterior ethmoidal foramina.
• These transmit nerves and vessels of the same name.

Tongue 
Appears at 4th week.
Musculature derived from mesoderm of occipital somites.  Precursor muscles cells migrate to region of tongue and are innervated by general sensory efferent fibers of CN XII.
Mucosa derived from anterior endoderm lining arches 1-4; accordingly, innervation depends on arch derivation:
              Mucosa of anterior 2/3 of tongue comes from the first arch -> CN V
              Mucosa of posterior 1/3 of tongue comes from third and forth arch -> CN IX, X
Special taste of anterior 2/3 of tongue comes from CN VII.
Special taste of posterior 1/3 of tongue comes from CN X.
Tongue freed from floor of mouth by extensive degeneration of underlying tissue.  Midline frenulum continues to anchor tongue to floor of mouth.

Thyroid Gland

Develops as in growth of mucosal epithelium located in the midline of the tongue (at foramen cecum).  It descends along front of pharyngeal gut, but remains connected to tongue by thyrooglossal duct, which is obliterated later in development.  Thyroid gland descends to a point just caudal to laryngeal cartilages. 

Facial structures (general)

a) medial nasal prominence forms midline of nose, philtrum and primary palate
b) lateral nasal prominence forms alae of nose
c) maxillary prominence forms cheek region and lateral lip
d) clefts can form at inter-prominence fusion lines

Nose

At the time of anterior neural tube closure, mesenchyme around forebrain, frontonasal prominence (FNP), has smooth rounded extended contour.  Nasal placodes (thickening of surface ectoderm to become peripheral neural tissue) develop on frontolateral aspects of FNP.  Mesenchyme swells around nasal placode producing a medial and lateral nasal prominence (nasomedial and nasolateral processes).  These nasal prominences form the nose.

Mouth 

Stomadeum (primitive oral cavity) forms between frontonasal prominence and first pharyngeal arch.  The first pharyngeal arch forms the dorsal maxillary prominence and ventral mandibular prominence.  The maxillary prominence will merge with medial nasal prominences, pushing them closer to cause fusion.  Fused medial nasal prominences will form midline of nose and midline of upper lip (philtrum) and primary palate (first 4 teeth).

Nasolacrimal structures

Maxillary and lateral nasal prominences are separated by deep furrow, the nasolacrimal groove.  Ectoderm in floor of groove forms epithelial cord, which detaches from overlying ectoderm.  The epithelial cord canalizes to form the nasolacrimal duct.  The upper end of the duct widens to form the lacrimal sac.  After detachment of the cord, the maxillary and lateral nasal prominences merge with each other, resulting in the formation of a nasolacrimal duct that runs from the medial corner of the eye to the inferior meatus of the nasal cavity.  
The maxillary prominences enlarge to form the cheeks and maxillae.
The lateral nasal prominences form the alae of the nose.

Secondary (hard) palate

Main part of definitive palate formed by two palatine shelves derived from intraoral bilateral extensions of the maxillary prominences.  These appear at the 6th week.  They are directed obliquely downward on each side of the tongue; they move down when mandible gets bigger.  
At the seventh week, they ascend to attain a horizontal position, then fuse to form the secondary palate.  At the time the palatine shelves fuse, the nasal septum (an outgrowth of median tissue of the frontonasal prominence) grows down and joins the cephalic aspect of the newly formed palate
Anteriorly, shelves fuse with triangular primary palate.  The incisive foramen marks the midline between the primary and secondary palate.

External Ear

The auricle is derived from 6 auricular hillocks (mesenchymal proliferations) along the dorsal aspect of arches 1 (top of ear) and 2 (bottom of ear).  These fuse to form the definitive auricle.  At the mandible grows, the ear is pushed upward and backward from its initial horizontal position on the neck.
The EAM is derived from the 1st pharyngeal arch.  
The eardrum (tympanic membrane) is composed of 3 layers of cells: 1) ectodermal epithelial lining of bottom of EAM; 2) endodermal epithelium lining of tympanic cavity; 3) intermediate layer of connective tissue.
The eardrum is composed of multiple cell layers because it represents the first pharyngeal membrane, and thus lies at the junction of the first pharyngeal pouch and cleft.

Middle Ear

The middle ear consists of an auditory tube (from the 1st pharyngeal pouch, along with tympanic cavity) and the ossicles (from pharyngeal arches 1 and 2 cartilage).  
The first arch cartilage forms the malleus and incus.  The tensor tympani (muscle of the malleus) is derived from the fourth somitomere (associated with the first arch) and is therefore innervated by CN V.
The second arch cartilage forms the stapes.  The stapedius (muscles of the stapes) is derived from the sixth somitomere (associated with the second arch) and is therefore innervated by CN VII.
The ossicles are initially embedded in mesenchyme, but in the 8th month, the mesenchyme degenerates and an endodermal epithelial lining of the tympanic cavity envelops the ossicles and connects them to the wall of the cavity in a mesentery-like fashion.

Inner Ear

The inner ear is derived thickening of surface ectoderm on both sides of the hindbrain (otic placodes).  The placodes invaginate to form otic vesicles (otocytes).  The vesicles then divide into ventral and dorsal components.
The ventral component forms the saccule and cochlear duct.
The dorsal component forms the utricle and semicircular canals and endolymphatic duct.

Cochlear Duct

Derived from an outgrowth of the saccule during the 6th week.  The outgrowth penetrates the surrounding mesenchyme in a spiral fashion.  The surrounding mesenchyme forms the cartilage and undergoes vacuolization.
The scala vestibule and scale tympani form and surround the cochlear duct.  They are filled with periplymp to receive mechanical vibrations of ossicles. The mechanical stimuli activates sensory (ciliary) cells in the cochlear duct.  

Semicircular canals

The utricle is initially three flattened outpocketings, which lose the central core.  From this three semicircular canals are forms, each at 90 degree angles from one another.  Sensory cells arise in the ampulla at one end of each canal, in the utricle and saccule. 

• BONES OF THE CRANIUM   Occipital (1) Frontal    (1) Sphenoid (1) Ethmoid  (1) Parietal    (2) Temporal  (2)

  BONES OF THE FACE   Mandible (1) Vomer     (1) Maxillae  (2) Zygomae  (2) Lacrimal   (2) Nasal        (2) Inferior nasal conchae (2) Palatine     (2)

   

• Long bones (e.g.. femur and humerus)
• Short bones (e.g.. wrist and ankle bones)
• Flat bones (e.g.. ribs)
• Irregular bones (e.g.. vertebrae)

The Paranasal Sinuses

• These sinuses are air-filled extensions of the respiratory part of the nasal cavity.
• They are in the following bones, frontal, ethmoid, sphenoid and the maxilla.

The Frontal Sinuses

• These are located between the outer and inner tables of the frontal bone, posterior to the superciliary arches.

The Ethmoidal Sinuses

• These comprise of several small cavities, called ethmoidal air cells, within the ethmoidal labyrinth (G. labyrinthos, a maze) of the lateral mass of the ethmoid bone.

The Sphenoidal Sinuses

• These occupy a variable amount in the body of the sphenoid bone and may extend into the wings.

The Maxillary Sinuses

• These are the largest pair of paranasal sinuses.
• They are pyramidal-shaped cavities that may occupy the entire bodies of the maxillae.