NEET MDS Lessons
Anatomy
Eye
At week 4, two depressions are evident on each of the forebrain hemispheres. As the anterior neural fold closes, the optic pits elongate to form the optic vesicles. The optic vesicles remain connected to the forebrain by optic stalks.
The invagination of the optic vesicles forms a bilayered optic cup. The bilayered cup becomes the dual layered retina (neural and pigmented layer)
Surface ectoderm forms the lens placode, which invaginates with the optic cup.
The optic stalk is deficient ventrally to contain choroids fissure to allow blood vessels into the eye (hyaloid artery). The artery feeds the growing lens, but will its distal portion will eventually degenerate such that the adult lens receives no hyaloid vasculature.
At the 7th week, the choroids fissure closes and walls fuse as the retinal nerve get bigger.
The anterior rim of the optic vesicles forms the retina and iris. The iris is an outgrowth of the distal edge of the retina.
Optic vesicles induces/maintains the development of the lens vesicle, which forms the definitive lens. Following separation of the lens vesicle from the surface ectoderm, the cornea develops in the anterior 1/5th of the eye.
The lens and retina are surrounded by mesenchyme which forms a tough connective tissue, the sclera, that is continuous with the dura mater around the optic nerve.
Iridopupillary membrane forms to separate the anterior and posterior chambers of the eye. The membrane breaks down to allow for the pupil
Mesenchyme surrounding the forming eye forms musculature (ciliary muscles and pupillary muscles – from somitomeres 1 and 2; innervated by CN III), supportive connective tissue elements and vasculature.
Eyelids
Formed by an outgrowth of ectoderm that is fused at its midline in the 2nd trimester, but later reopen.
-
BONES OF THE CRANIUM
Occipital (1)
Frontal (1)
Sphenoid (1)
Ethmoid (1)
Parietal (2)
Temporal (2)
BONES OF THE FACE
Mandible (1)
Vomer (1)
Maxillae (2)
Zygomae (2)
Lacrimal (2)
Nasal (2)
Inferior nasal conchae (2)
Palatine (2)
- Bones begin to form during the eighth week of embryomic life in the fibrous membranes (intramembranous ossification) and hyaline cartilage (endochondral ossification)
The Palate
- The palate forms the arched roof of the mouth and the floor of the nasal cavities.
- The palate consists of two regions: the anterior 2/3 or bony part, called the hard palate, and the mobile posterior 1/3 or fibromuscular part, known as the soft palate.
The External Ear
- The auricle (L. auris, ear) is the visible, shell-like part of the external ear.
- It consists of a single elastic cartilage that is covered on both surfaces with thin, hairy skin.
- The external ear contains hairs, sweat glands, and sebaceous glands.
- The cartilage is irregularly ridged and hollowed, which gives the auricle its shell-like form.
- It also shapes the orifice of the external acoustic meatus.
The Ear Lobule
- The ear lobule (earlobe) consists of fibrous tissue, fat and blood vessels that are covered with skin.
- The arteries are derived mainly from the posterior auricular artery and the superficial temporal artery.
- The skin of the auricle is supplied by the great auricular and auriculotemporal nerves.
- The great auricular nerve supplies the superior surface and the lateral surface inferior to the external acoustic meatus with nerve fibres from C2.
- The auriculotemporal nerve supplies the skin of the auricle superior to the external acoustic meatus.
The External Acoustic Meatus
- This passage extends from the concha (L. shell) of the auricle to the tympanic membrane (L. tympanum, tambourine). It is about 2.5 cm long in adults.
- The lateral 1/3 of the S-shaped canal is cartilaginous, whereas its medial 2/3 is bony.
- The lateral third of the meatus is lined with the skin of the auricle and contains hair follicles, sebaceous glands, and ceruminous glands.
- The latter glands produce cerumen (L. cera, wax).
- The medial two-thirds of the meatus is lined with very thin skin that is continuous with the external layer of the tympanic membrane.
- The lateral end of the meatus is the widest part. It has the diameter about that of a pencil.
- The meatus becomes narrow at its medial end, about 4 mm from the tympanic membrane.
- The constricted bony part is called the isthmus.
- Innervation of the external acoustic meatus is derived from three cranial nerves:
- The auricular branch of the auriculotemporal nerve (derived from the mandibular, CN V3).
- The facial nerve (CN VII) by the branches from the tympanic plexus.
- The auricular branch of the vagus nerve (CN X).
The Tympanic Membrane
- This is a thin, semi-transparent, oval membrane at the medial end of the external acoustic meatus.
- It forms a partition between the external and middle ears.
- The tympanic membrane is a thin fibrous membrane, that is covered with very thin skin externally and mucous membrane internally.
- The tympanic membrane shows a concavity toward the meatus with a central depression, the umbo, which is formed by the end of the handle of the malleus.
- From the umbo, a bright area referred to as the cone of light, radiates anteroinferiorly.
- The external surface of the tympanic membrane is supplied by the auriculotemporal nerve.
- Some innervation is supplied by a small auricular branch of the vagus nerve (CN X); this nerve may also contain some glossopharyngeal and facial nerve fibres.
|
Muscle
|
Emotion
|
|
Epicranius
|
Surprise
|
|
Orbicularisoculi
|
Squinting
|
|
Orbicularisoris |
Pouting |
|
Nasalis
|
Smelling
|
|
Zygomaticus
|
Smiling
|
|
Buccinator
|
Chewing
|
|
Mentalis
|
Doubt
|
|
Triangularis
|
Sadness
|
|
Platysma
|
Sadness
|
|
Masseter
|
Chewing
|
|
Temporalis
|
Sternness
|
|
Pterygoid
|
Conternation
|
|
Genioglossus and Styloglossus
|
Swallowing, Speaking, Chewing
|
Intramembranous ossification
- Flat bones develop in this way (bones of the skull)
- This type of bone development takes place in mesenchymal tissue
- Mesenchymal cells condense to form a primary ossification centre (blastema)
- Some of the condensed mesenchymal cells change to osteoprogenitor cells
- Osteoprogenitor cells change into osteoblasts which start to deposit bone
- As the osteoblasts deposit bone some of them become trapped in lacunae in the bone and then change into osteocytes
- Osteoblasts lie on the surface of the newly formed bone
- As more and more bone is deposited more and more osteocytes are formed from mesenchymal cells
- The bone that is formed is called a spicule
- This process takes place in many places simultaneously
- The spicules fuse to form trabeculae
- Blood vessels grow into the spaces between the trabeculae
- Mesenchymal cells in the spaces give rise to hemopoetic tissue
- This type of bone development forms the first phase in endochondral development
- It is also responsible for the growth of short bones and the thickening of long bones