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Anatomy - NEETMDS- courses
NEET MDS Lessons
Anatomy

Eye 

At week 4, two depressions are evident on each of the forebrain hemispheres.  As the anterior neural fold closes, the optic pits elongate to form the optic vesicles.  The optic vesicles remain connected to the forebrain by optic stalks. 
The invagination of the optic vesicles forms a bilayered optic cup.  The bilayered cup becomes the dual layered retina (neural and pigmented layer)
Surface ectoderm forms the lens placode, which invaginates with the optic cup.
The optic stalk is deficient ventrally to contain choroids fissure to allow blood vessels into the eye (hyaloid artery).  The artery feeds the growing lens, but will its distal portion will eventually degenerate such that the adult lens receives no hyaloid vasculature.
At the 7th week, the choroids fissure closes and walls fuse as the retinal nerve get bigger.
The anterior rim of the optic vesicles forms the retina and iris.  The iris is an outgrowth of the distal edge of the retina.
Optic vesicles induces/maintains the development of the lens vesicle, which forms the definitive lens.  Following separation of the lens vesicle from the surface ectoderm, the cornea develops in the anterior 1/5th of the eye.
The lens and retina are surrounded by mesenchyme which forms a tough connective tissue, the sclera, that is continuous with the dura mater around the optic nerve.  
Iridopupillary membrane forms to separate the anterior and posterior chambers of the eye.  The membrane breaks down to allow for the pupil
Mesenchyme surrounding the forming eye forms musculature (ciliary muscles and pupillary muscles – from somitomeres 1 and 2; innervated by CN III), supportive connective tissue elements and vasculature.


Eyelids

Formed by an outgrowth of ectoderm that is fused at its midline in the 2nd trimester, but later reopen.

The Parotid Glands

  • The parotid glands are the largest of the three pairs of salivary glands.
  • Each gland is wedged between the mandible and the sternocleidomastoid muscle and partly covers them.
  • The parotid gland is wrapped with a fibrous capsule (parotid fascia) that is continuous with the deep investing fascia of the neck.
  • Viewed superficially, the parotid gland is somewhat triangular in shape.
  • Its apex is posterior to the angle of the mandible and its base is along the zygomatic arch.
  • The parotid gland overlaps the posterior part of the masseter muscle.
  • The parotid duct (Stensen's duct) is about 5 cm long and 5 mm in diameter.
  • It passes horizontally from the anterior edge of the gland.
  • At the anterior border of the masseter muscle, the parotid duct turns medially and pierces the buccinator muscle.
  • It enters the oral cavity opposite the second maxillary molar.

 

Blood Vessels of the Parotid Gland

  • This gland is supplied by branches of the external carotid artery.
  • The veins from the parotid gland drains into the retromandibular vein, which enters the internal jugular vein.

 

Lymphatic Drainage of the Parotid Gland

  • The lymph vessels of this gland end in the superficial and deep cervical lymph nodes.

 

Nerves of the Parotid Gland

  • These nerves are derived from the auriculotemporal nerve and from the sympathetic and parasympathetic systems.
  • The parasympathetic fibres are derived from the glossopharyngeal nerve (CN IX) through the otic ganglion.
  • Stimulation of these fibres produces a thin watery (serous) saliva to flow from the parotid duct.
  • The sympathetic fibres are derived from the cervical ganglia through the external carotid plexus.
  • Stimulation of these fibres produces a thick mucous saliva.

Internal Muscles of the Pharynx

  • The internal, chiefly longitudinal muscular layer, consists of 3 muscles: stylopharyngeus, palatopharyngeus, and salpingopharyngeus.
  • They all elevate the larynx and pharynx during swallowing and speaking.

The Stylopharyngeus Muscle

  • This is a long, thin, conical muscles that descends inferiorly between the external and internal carotid arteries.
  • It enters the wall of the pharynx between the superior and middle constrictor muscles.
  • Origin: styloid process of temporal bone.
  • Insertion: posterior and superior borders of thyroid cartilage with palatopharyngeus muscle.
  • Innervation: glossopharyngeal nerve (CN IX).
  • It elevates the pharynx and larynx and expands the sides of the pharynx, thereby aiding in pulling the pharyngeal wall over a bolus of food.

The Palatopharyngeus Muscle

  • This is a thin muscle and the overlying mucosa form the palatopharyngeal arch.

The Salpingopharyngeus Muscle

  • This is a slender muscle that descends in the lateral wall of the pharynx.
  • The over lying mucous membrane forms the salpingopharyngeal fold.
  • Origin: cartilaginous part of the auditory tube.
  • Insertion: blends with palatopharyngeus muscle.
  • Innervation: through the pharyngeal plexus.
  • It elevates the pharynx and larynx and opens the pharyngeal orifice of the auditory tube during swallowing.

-> This bone forms much of the base and posterior aspect of the skull.
-> It has a large opening called the foramen magnum, through which the cranial cavity communicates with the vertebral canal.
-> It is also where the spinal cord becomes continuous with the medulla (oblongata) of the brain stem.
-> The occipital bone is saucer-shaped and can be divided into four parts: a squamous part (squama), a basilar part (basioccipital part), and two lateral parts (condylar parts).
-> These four parts develop separately around the foramen magnum and unite at about the age of 6 years to form one bone.
-> On the inferior surfaces of the lateral parts of the occipital bone are occipital condyles, where the skull articulates with C1 vertebra (the atlas) at the atlanto-occipital joints.
-> The internal aspect of the squamous part of the occipital bone is divided into four fossae: the superior two for the occipital poles of the cerebral hemispheres, and the inferior two, called cerebellar fossae, for the cerebellar hemispheres.

 

  • This is the second cranial nerve (CN II) and is the nerve of sight.

CARTILAGE

There are 3 types:

Hyaline cartilage
Elastic cartilage
Fibrocartilage

Matrix is made up by: Hyaluronic acid

Proteoglycans

 

- In cartilage the protein core of the proteoglycan molecule binds through a linking protein to hyaluronic acid to form a proteoglycan aggregate which binds to the fibres

- In the matrix there are spaces, lacunae in which one to three of the cells of cartilage, chondrocytes, are found

- The matrix around the lacuna is the territorial matrix

- Type II collagen fibrils are embedded in the matrix

- The type of fiber depends on the type of cartilage

- Cartilage is surrounded by perichondrium which is a dense CT

- Apositional growth takes place in the perichondrium

- The fibroblasts of the perichondrium change to elliptic chondroblasts which later change to round chondrocytes

- Interstitial growth takes place around the lacunae

- Nutrients diffuse through the matrix to get to the chondrocytes   this limits the thickness of cartilage

Hyaline cartilage

Found: Rib cartilage,  articulating surfaces,  nose,  larynx, trachea, embryonic skeleton, Articulating cartilage has no perichondrium

 Bluish-white and translucent

Contains type II collagen that is not visible

 

Elastic cartilage

Found:  external auditory canal,  epiglottis

Similar to hyaline except that it contains many elastic fibres ,Yellow in colour,  Can be continuous with hyaline

Fibrocartilage

Found: Intervertebral disk, symphysis pubis

Always associated with dense CT,  Many collagen fibres in the matrix, No perichondrium

- Chondrocytes tend to lie in rows, Can withstand strong forces

The Lips

  • These are mobile muscular folds that surround the mouth, the entrance of the oral cavity.
  • The lips (L. labia) are covered externally by skin and internally by mucous membrane.
  • In between these are layers of muscles, especially the orbicularis oris muscle.
  • The upper and lower lips are attached to the gingivae in the median plane by raised folds of mucous membrane, called the labial frenula.

Sensory Nerves of the Lips

  • The sensory nerves of the upper and lower lips are from the infraorbital and mental nerves, which are branches of the maxillary (CN V2) and mandibular (CN V3) nerves.

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