SHOCK

Shock  is  defined  as  a  pathological  state  causing  inadequate  oxygen  delivery  to  the peripheral tissues and resulting in lactic acidosis, cellular hypoxia and disruption of normal metabolic condition.

CLASSIFICATION

Shock is generally classified into three major categories:

1.    Hypovolemic shock

2.    Cardiogenic shock

3.    Distributive shock

Distributive shock is further subdivided into three subgroups:

a.    Septic shock

b.    Neurogenic shock

c.    Anaphylactic shock

Hypovolemic  shock  is  present  when  marked  reduction  in  oxygen  delivery results from diminished cardiac output secondary to inadequate vascular volume. In general, it results from loss of fluid from circulation, either directly or indirectly.
e.g.    ?    Hemorrhage
    •    Loss of plasma due to burns
    •    Loss of water and electrolytes in diarrhea
    •    Third space loss (Internal fluid shift into inflammatory exudates in
        the peritoneum, such as in pancreatitis.)

Cardiogenic shock is present when there is severe reduction in oxygen delivery secondary to impaired cardiac function. Usually it is due to myocardial infarction or pericardial tamponade.

Septic Shock (vasogenic shock) develops as a result of the systemic effect of infection. It is the result of a septicemia with endotoxin and exotoxin release by gram-negative and gram-positive bacteria. Despite normal or increased cardiac output and oxygen delivery, cellular oxygen consumption is less than normal due to impaired extraction as a result of impaired metabolism.

Neurogenic shock results primarily from the disruption of the sympathetic nervous system which may be due to pain or loss of sympathetic tone, as in spinal cord injuries.

PATHO PHYSIOLOGY OF SHOCK

Shock stimulates a physiologic response. This circulatory response to hypotension is to conserve perfusion to the vital organs (heart and brain) at the expense of other tissues. Progressive vasoconstriction of skin, splanchnic and renal vessels leads to renal cortical necrosis and acute renal failure. If not corrected in time, shock leads to organ failure and sets up a vicious circle with hypoxia and acidosis.

CLINICAL FEATURES

The clinical presentation varies according to the cause. But in general patients with hypotension and reduced tissue perfusion presents with:
•    Tachycardia
•    Feeble pulse
•    Narrow pulse pressure
•    Cold extremities (except septic shock)
•    Sweating, anxiety
•    Breathlessness / Hyperventilation
•    Confusion leading to unconscious state

PATHO PHYSIOLOGY OF SHOCK

Shock stimulates a physiologic response. This circulatory response to hypotension is to conserve perfusion to the vital organs (heart and brain) at the expense of other tissues. Progressive vasoconstriction of skin, splanchnic and renal vessels leads to renal cortical necrosis and acute renal failure. If not corrected in time, shock leads to organ failure and sets up a vicious circle with hypoxia and acidosis.

CLINICAL FEATURES

The clinical presentation varies according to the cause. But in general patients with hypotension and reduced tissue perfusion presents with:
•    Tachycardia
•    Feeble pulse
•    Narrow pulse pressure
•    Cold extremities (except septic shock)
•    Sweating, anxiety
•    Breathlessness / Hyperventilation
•    Confusion leading to unconscious state

Ludwig's Angina

Ludwig's angina is a serious, potentially life-threatening cellulitis or connective tissue infection of the submandibular space. It typically arises from infections of the teeth, particularly the second or third molars, and can lead to airway obstruction due to swelling. This condition is named after the German physician Wilhelm Friedrich von Ludwig, who first described it in the 19th century.

Etiology

• Common Causes:

  • Dental infections (especially from the lower molars)
  • Infections from the floor of the mouth
  • Trauma to the submandibular area
  • Occasionally, infections can arise from other sources, such as the oropharynx or skin.

• Microbial Agents:

  • Mixed flora, including both aerobic and anaerobic bacteria.
  • Common organisms include Streptococcus, Staphylococcus, and Bacteroides species.

Pathophysiology

• The infection typically begins in the submandibular space and can spread rapidly due to the loose connective tissue in this area.
• The swelling can lead to displacement of the tongue and can obstruct the airway, making it a medical emergency.

Clinical Presentation

• Symptoms:

  • Swelling of the submandibular area, which may be bilateral
  • "Brawny induration" (firm, non-fluctuant swelling)
  • Pain and tenderness in the submandibular region
  • Difficulty swallowing (dysphagia) and speaking (dysarthria)
  • Fever and malaise
  • Possible elevation of the floor of the mouth and displacement of the tongue

• Signs:

  • Swelling may extend to the neck and may cause "bull neck" appearance.
  • Trismus (limited mouth opening) may be present.
  • Respiratory distress due to airway compromise.

Diagnosis

• Clinical Evaluation: Diagnosis is primarily clinical based on history and physical examination.
• Imaging:
  • CT scan of the neck may be used to assess the extent of the infection and to rule out other conditions.
  • X-rays may show air in the soft tissues if there is a necrotizing infection.

Management

Initial Management

• Airway Management:
  • Ensure the airway is patent; this may require intubation or tracheostomy in severe cases.

Medical Treatment

• Antibiotics:
  • Broad-spectrum intravenous antibiotics are initiated to cover both aerobic and anaerobic bacteria. Common regimens may include:
    • Ampicillin-sulbactam
    • Clindamycin
    • Metronidazole combined with a penicillin derivative

Surgical Intervention

• Drainage:
  • Surgical drainage may be necessary if there is an abscess formation or significant swelling.
  • Incisions are typically made in the submandibular area to allow for drainage of pus and to relieve pressure.

Complications

• Airway Obstruction: The most critical complication, requiring immediate intervention.
• Sepsis: Can occur if the infection spreads systemically.
• Necrotizing fasciitis: Rare but serious complication that may require extensive surgical intervention.
• Thrombosis of the internal jugular vein: Can occur due to the spread of infection.

Prognosis

• With prompt diagnosis and treatment, the prognosis is generally good. However, delays in management can lead to significant morbidity and mortality due to airway compromise and systemic infection.

Advanced Trauma Life Support (ATLS)

Introduction

Trauma is a leading cause of death, particularly in the first four decades of life, and ranks as the third most common cause of death overall. The Advanced Trauma Life Support (ATLS) program was developed to provide a systematic approach to the management of trauma patients, ensuring that life-threatening conditions are identified and treated promptly.

Mechanisms of Injury

In trauma, injuries can be classified based on their mechanisms:

Overt Mechanisms

1. Penetrating Trauma: Injuries caused by objects that penetrate the skin and underlying tissues.
2. Blunt Trauma: Injuries resulting from impact without penetration, such as collisions or falls.
3. Thermal Trauma: Injuries caused by heat, including burns.
4. Blast Injury: Injuries resulting from explosions, which can cause a combination of blunt and penetrating injuries.

Covert Mechanisms

1. Blunt Trauma: Often results in internal injuries that may not be immediately apparent.
2. Penetrating Trauma: Can include knife wounds and other sharp objects.
3. Penetrating Knife: Specific injuries from stabbing.
4. Gunshot Injury: Injuries caused by firearms, which can have extensive internal damage.

The track of penetrating injuries can often be identified by the anatomy involved, helping to determine which organs may be injured.

Steps in ATLS

The ATLS protocol consists of a systematic approach to trauma management, divided into two main surveys:

1. Primary Survey

• Objective: Identify and treat life-threatening conditions.
• Components:
  • A - Airway: Ensure the airway is patent. In patients with a Glasgow Coma Scale (GCS) of 8 or less, immediate intubation is necessary. Maintain cervical spine stability.
  • B - Breathing: Assess ventilation and oxygenation. Administer high-flow oxygen via a reservoir mask. Identify and treat conditions such as tension pneumothorax, flail chest, massive hemothorax, and open pneumothorax.
  • C - Circulation: Evaluate circulation based on:
    • Conscious level (indicates cerebral perfusion)
    • Skin color
    • Rapid, thready pulse (more reliable than blood pressure)
  • D - Disability: Assess neurological status using the Glasgow Coma Scale (GCS).
  • E - Exposure: Fully expose the patient to assess for injuries on the front and back.

2. Secondary Survey

• Objective: Conduct a thorough head-to-toe examination to identify all injuries.
• Components:
  • AMPLE: A mnemonic to gather important patient history:
    • A - Allergy: Any known allergies.
    • M - Medications: Current medications the patient is taking.
    • P - Past Medical History: Relevant medical history.
    • L - Last Meal: When the patient last ate.
    • E - Events of Incident: Details about the mechanism of injury.

Triage

Triage is the process of sorting patients based on the severity of their condition. The term "triage" comes from the French word meaning "to sort." In trauma settings, patients are categorized using a color-coded system:

• Red: First priority (critical patients, e.g., tension pneumothorax).
• Yellow: Second priority (urgent cases, e.g., pelvic fracture).
• Green: Third priority (minor injuries, e.g., simple fracture).
• Black: Zero priority (patients who are dead or unsalvageable).

Blunt Trauma

• Common Causes: The most frequent cause of blunt trauma is road traffic accidents.
• Seat Belt Use: Wearing seat belts significantly reduces mortality rates:
  • Front row occupants: 45% reduction in death rate.
  • Rear seat belt use: 80% reduction in death rate for front seat occupants.
• Seat Belt Injuries: Marks on the thorax indicate a fourfold increase in thoracic injuries, while abdominal marks indicate a threefold increase in abdominal injuries.

Radiographs in Trauma

Key radiographic views to obtain in trauma cases include:

1. Lateral cervical spine
2. Anteroposterior chest
3. Anteroposterior pelvis

Excision of Lesions Involving the Jaw Bone

When excising lesions involving the jaw bone, various terminologies are used to describe the specific techniques and outcomes of the procedures.

1. Enucleation

• Enucleation refers to the separation of a lesion from the bone while preserving bone continuity. This is achieved by removing the lesion along an apparent tissue or cleavage plane, which is often defined by an encapsulating or circumscribing connective tissue envelope derived from the lesion or surrounding bone.
• Key Characteristics:
  • The lesion is contained within a defined envelope.
  • Bone continuity is maintained post-excision.

2. Curettage

• Curettage involves the removal of a lesion from the bone by scraping, particularly when the lesion is friable or lacks an intact encapsulating tissue envelope. This technique may result in the removal of some surrounding bone.
• Key Characteristics:
  • Indicates the inability to separate the lesion along a distinct tissue plane.
  • May involve an inexact or immeasurable thickness of surrounding bone.
  • If a measurable margin of bone is removed, it is termed "resection without continuity defect."

3. Marsupialization

• Marsupialization is a surgical procedure that involves the exteriorization of a lesion by removing overlying tissue to expose its internal surface. This is done by excising a portion of the lesion bordering the oral cavity or another body cavity.
• Key Characteristics:
  • Multicompartmented lesions are rendered unicompartmental.
  • The lesion is clinically cystic, and the excised tissue may include bone and/or overlying mucosa.

4. Resection Without Continuity Defect

• This term describes the excision of a lesion along with a measurable perimeter of investing bone, without interrupting bone continuity. The anatomical relationship allows for the removal of the lesion while preserving the integrity of the bone.
• Key Characteristics:
  • Bone continuity is maintained.
  • Adjacent soft tissue may be included in the resection.

5. Resection With Continuity Defect

•  This involves the excision of a lesion that results in a defect in the continuity of the bone. This is often associated with more extensive resections.
• Key Characteristics:
  • Bone continuity is interrupted.
  • May require reconstruction or other interventions to restore function.

6. Disarticulation

•  Disarticulation is a special form of resection that involves the temporomandibular joint (TMJ) and results in a continuity defect.
• Key Characteristics:
  • Involves the removal of the joint and associated structures.
  • Results in loss of continuity in the jaw structure.

7. Recontouring

•  Recontouring refers to the surgical reduction of the size and/or shape of the surface of a bony lesion or bone part. The goal is to reshape the bone to conform to the adjacent normal bone surface or to achieve an aesthetic result.
• Key Characteristics:
  • May involve lesions such as bone hyperplasia, torus, or exostosis.
  • Can be performed with or without complete eradication of the lesion (e.g., fibrous dysplasia).

Suture Materials

Sutures are essential in surgical procedures for wound closure and tissue approximation. Various types of sutures are available, each with unique properties, advantages, and applications. Below is a summary of some commonly used suture materials, including chromic catgut, polypropylene, polyglycolic acid, and polyamide (nylon).

1. Chromic Catgut

• Description:

  • Chromic catgut is a natural absorbable suture made from collagen derived from the submucosa of sheep intestines or the serosa of beef cattle intestines. It is over 99% pure collagen.

• Absorption Process:

  • The absorption of chromic catgut occurs through enzymatic digestion by proteolytic enzymes, which are derived from lysozymes contained within polymorphonuclear leukocytes (polymorphs) and macrophages.

• Absorption Rate:

  • The absorption rate depends on the size of the suture and whether it is plain or chromicized. Typically, absorption is completed within 60-120 days.

• Applications:

  • Commonly used in soft tissue approximation and ligation, particularly in areas where a temporary support is needed.

2. Polypropylene (Proline)

• Description:

  • Polypropylene is a synthetic monofilament suture made from a purified and dyed polymer.

• Properties:

  • It has an extremely high tensile strength, which it retains indefinitely after implantation. Polypropylene is non-biodegradable, meaning it does not break down in the body.

• Applications:

  • Ideal for use in situations where long-term support is required, such as in vascular surgery, hernia repairs, and other procedures where permanent sutures are beneficial.

3. Polyglycolic Acid

• Description:

  • Polyglycolic acid is a synthetic absorbable suture formed by linking glycolic acid monomers to create a polymer.

• Properties:

  • It is known for its predictable absorption rate and is commonly used in various surgical applications.

• Applications:

  • Frequently used in soft tissue approximation, including in gastrointestinal and gynecological surgeries, where absorbable sutures are preferred.

4. Polyamide (Nylon)

• Description:

  • Polyamide, commonly known as nylon, is a synthetic non-absorbable suture that is chemically extruded and generally available in monofilament form.

• Properties:

  • Nylon sutures have a low coefficient of friction, making passage through tissue easy. They also elicit minimal tissue reaction.

• Applications:

  • Used in a variety of surgical procedures, including skin closure, where a strong, durable suture is required.

Dautrey Procedure

The Dautrey procedure is a surgical intervention aimed at preventing dislocation of the temporomandibular joint (TMJ) by creating a mechanical obstacle that restricts abnormal forward translation of the condylar head. This technique is particularly beneficial for patients who experience recurrent TMJ dislocations or subluxations, especially when conservative management strategies have proven ineffective.

1. Indications:

   • The Dautrey procedure is indicated for patients with a history of recurrent TMJ dislocations. It is particularly useful when conservative treatments, such as physical therapy or splint therapy, have failed to provide adequate stabilization of the joint.

2. Surgical Technique:

   • Osteotomy of the Zygomatic Arch: The procedure begins with an osteotomy, which involves surgically cutting the zygomatic arch, the bony structure that forms the prominence of the cheek.
   • Depressing the Zygomatic Arch: After the osteotomy, the zygomatic arch is depressed in front of the condylar head. This depression creates a physical barrier that acts as an obstacle to the forward movement of the condylar head during jaw opening or excessive movement.
   • Stabilization: The newly positioned zygomatic arch limits the range of motion of the condylar head, thereby reducing the risk of dislocation during functional activities such as chewing or speaking.

3. Mechanism of Action:

   • By altering the position of the zygomatic arch, the Dautrey procedure effectively changes the biomechanics of the TMJ. The new position of the zygomatic arch prevents the condylar head from translating too far forward, which is a common cause of dislocation.

4. Postoperative Care:

   • Following the procedure, patients may require a period of recovery and rehabilitation. This may include:
     • Dietary Modifications: Soft diet to minimize stress on the TMJ during the healing process.
     • Pain Management: Use of analgesics to manage postoperative discomfort.
     • Physical Therapy: Exercises to restore normal function and range of motion in the jaw.

5. Outcomes:

   • The Dautrey procedure has been shown to be effective in preventing recurrent TMJ dislocations. Patients often experience improved joint stability and a better quality of life following the surgery. Successful outcomes can lead to reduced pain, improved jaw function, and enhanced overall satisfaction with treatment.