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Oral Pathology - NEETMDS- courses
NEET MDS Lessons
Oral Pathology

Miescher Cheilitis

  • Definition: Granulomatous inflammation confined to the lip

Melkersson–Rosenthal Syndrome

Triad:

  1. Facial palsy
  2. Cheilitis granulomatosa
  3. Fissured tongue

Ascher Syndrome

Triad:

  1. Double lip
  2. Blepharochalasis
  3. Nontoxic thyroid enlargement

Double Lip

  • Appearance: Cupid's bow

  • Calcifying Odontogenic Cyst (COC) / Gorlin Cyst: Characterized by Ghost Cells.

  • Aneurysmal Bone Cyst (ABC): Associated with a "blood-soaked" appearance on gross examination.

  • Radicular Cyst - Common Site: Maxillary anterior teeth (due to higher incidence of trauma).

  • Odontogenic Keratocyst (OKC) / Keratocystic Odontogenic Tumor (KCOT):

    • Most common site: Posterior mandible (similar to ameloblastoma).

    • Expansion: Tends to expand antero-posteriorly; buccal and lingual expansion seen in late stages.

    • Basal layer histology: Tall columnar cells with palisaded nuclei – "row of tombstones" or "picket fence appearance."

    • Classification: Now considered a benign odontogenic neoplasm (KCOT) in recent WHO classifications.

  • Retention Cyst of Maxillary Sinus: Characteristic X-ray feature is a dome-shaped/hemispherical radio-opacity in the antrum.

  • Abfraction: Appears as a subgingival, deep, narrow "V" shaped notch in the cervical areas of teeth.

  • Abrasion vs. Abfraction:

    • Abrasion: Commonly affects cuspids and bicuspids.

    • Abfraction: Affects only a single tooth (adjacent tooth is unaffected).

  • Erosion (Gastric): Erosion due to gastric secretions is termed Perimolysis.

Infective osteomyelitis

  • Tuberculous osteomyelitis
  • Syphilitic osteomyelitis
  • Actinomycotic osteomyelitis

Tuberculous osteomyelitis

  • Non healing sinus tract formation
  • Age group affected is around 15 – 40 years.
  • Commonly seen in phalanges and dorsal and lumbar vertebrae.
  • Usually occurs secondary to tuberculosis of lungs.
  • Cases have been reported where mandibular lesions were not associated with pulmonary disease.
  • Another common entrance is through a carious tooth via open pulp.
  • Usually affects long bones and rare in jaws.
  • Results when blood borne bacilli lodge in cancellous bone. Usually in ramus , body of mandible. may mimic parotid swelling or submassetric abscess.

Syphilitic osteomyelitis

  • Difficult to distinguish syphilitic osteomyelitis of the jaws from pyogenic osteomyelitis on clinical & radiographic examination.
  • Main features are progressive course & failure to improve with usual treatment for pyogenic osteomyelitis.
  • Massive sequestration may occur resulting in pathologic fracture.
  • If unchecked, eventually causes perforation of the cortex.

Actinomycotic Osteomyelitis

  • The organisms thrive in the oral cavity, especially tissues adjacent to mandible.
  • May enter the bone through a fresh wound, carious tooth or a periodontal pocket at the gingival margin of erupting tooth.
  • Soft or firm tissue masses on skin, which have purplish, dark red, oily areas with occasional zones of fluctuation.
  • Spontaneous drainage of serous fluid containing granular material.
  • Regional lymph nodes occasionally enlarged.
  • Mimics parotitis / parotid tumors

Macroglossia

  • Feature: Crenated (scalloped) lateral tongue borders

Lymphangioma of Tongue

  • Appearance: Tapioca pudding/Frog's egg

Geographic Tongue

  • Associated With: Fissured tongue
  • Histopathology: Similar to psoriasis
  • Key Feature: Munro's abscesses

Median Rhomboid Glossitis

  • Unique Sign: "Kissing lesion" on soft palate due to tongue contact

Hairy Tongue

  • Misnomer: Elongated filiform papillae—not actual hair

Acute suppurative osteomyelitis

  • Serious sequela of periapical infection.
  • Leads to spread of pus through the medullary cavities of bone.
  • Depending upon the main site of involvement of bone, can be of two types-
  1. Acute intramedullary
  2. Acute subperiosteal

Acute Intramedullary Osteomyelitis

CLINICAL FEATURES:

  • Patient experiences dull , continuous pain , indurated swelling forms over the affected region of jaw involving the cheek , febrile.
  • When mandible involved, loss of sensation occurs on lower lip on affected side due to involvement of inferior alveolar nerve.
  • Teeth become loose later along with tender on percussion
  • Pus discharge , trismus , foul smell , regional lymphadenopathy , weakness

RADIOGRAPHIC FEATURES

  • Earliest radiographic change is that trabeculae in involved area are thin, of poor density & slightly blurred.
  • Subsequently multiple radiolucencies appear which become apparent on radiograph.
  • In some cases there is saucer shaped area of destruction with irregular margins.
  • Loss of continuity of lamina dura, seen in more than one tooth.

HISTOLOGIC FEATURES:

  • Dense infiltration of marrow by polymorphonuclear leukocytes.
  • Bone trabeculae in involved site (sequestrum) are devoid of cells in the lacunae.
  • separation of considerable portions of devitalized bone.

 

Acute Subperiosteal Osteomyelitis

CLINICAL FEATURES

  • Pain , febrile condition , i/o and e/o swelling , parasthesia
  • Bone involvement limited to localized areas of cortex.
  • Pus ruptures rapidly through the overlying cortex, tracks along the surface of mandible under the periosteal sheath.
  • Elevation of periosteum from cortex is followed eventually by minute cortical sequestration.

  • Solitary Bone Cyst (Traumatic Bone Cyst): Usually situated above the inferior dental canal.

  • Stafne's Bone Defect (Static Bone Cavity/Lingual Mandibular Bone Defect): Located below the inferior dental canal. (Note: Stafne's is a pseudocyst/developmental defect, not a true cyst).

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