Benign Migratory Glossitis

• Also called Erythema migrans, wandering rash, or geographic tongue.

• Associated with fissured tongue.

Fissured Tongue

• Seen in:

  • Melkersson-Rosenthal syndrome

  • Down syndrome

  • Benign migratory glossitis

Melkersson-Rosenthal Syndrome

• Triad:

  • Bell’s palsy

  • Cheilitis granulomatosa (lip/facial swelling)

  • Fissured tongue

Ankyloglossia

• Tongue-tie may cause speech defects.

• Affects articulation of: l, r, t, d, n, th, sh, z

• SLE → IgG, IgM, IgA deposits at BMZ + superficial lamina propria
• Lichen Planus (Erosive/Atrophic) → Autoimmune T-cell; BMZ involvement
• Cicatricial Pemphigoid → Subepidermal blistering from anti-BMZ antibodies

• Solitary Bone Cyst (Traumatic Bone Cyst): Usually situated above the inferior dental canal.

• Stafne's Bone Defect (Static Bone Cavity/Lingual Mandibular Bone Defect): Located below the inferior dental canal. (Note: Stafne's is a pseudocyst/developmental defect, not a true cyst).

• Stevens-Johnson Syndrome (SJS):

  • Characterized by ulcers with hemorrhagic crusts.

  • Typically has an acute onset following drug exposure (mainly sulfa group drugs).

• Biopsy for Vesiculobullous Pathology: Should be taken from the margin of the vesicle/bulla, including a significant amount of normal-appearing mucosa, to capture the pathological changes and adjacent healthy tissue for comparison.

• Linea Alba: A white, bilateral line on the buccal mucosa associated with pressure, frictional irritation, or sucking trauma from the facial surface of teeth.

• Morsicatio Buccarum: Chronic irritation seen on the buccal mucosa as a result of suction and glassblowers (chewing habits).

• Riga-Fede Disease: Sublingual ulcerations in infants resulting from chronic mucosal trauma from adjacent primary teeth (often natal/neonatal teeth).

Smoker's Palate & Melanosis

• Status: NOT premalignant
• Exception: Reverse smoking palatal changes ARE premalignant

Oral Submucous Fibrosis (OSMF)

Initial Stage:

• Vesicles may be present
• Dilated capillaries

Advanced Stage:

• Compressed capillaries due to fibrosis

Miescher Cheilitis

• Definition: Granulomatous inflammation confined to the lip

Melkersson–Rosenthal Syndrome

Triad:

1. Facial palsy
2. Cheilitis granulomatosa
3. Fissured tongue

Ascher Syndrome

Triad:

1. Double lip
2. Blepharochalasis
3. Nontoxic thyroid enlargement

Double Lip

• Appearance: Cupid's bow