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Periodontology - NEETMDS- courses
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Periodontology

Theories Regarding the Mineralization of Dental Calculus

Dental calculus, or tartar, is a hard deposit that forms on teeth due to the mineralization of dental plaque. Understanding the mechanisms by which plaque becomes mineralized is essential for dental professionals in managing periodontal health. The theories regarding the mineralization of calculus can be categorized into two main mechanisms: mineral precipitation and the role of seeding agents.

1. Mineral Precipitation

Mineral precipitation involves the local rise in the saturation of calcium and phosphate ions, leading to the formation of calcium phosphate salts. This process can occur through several mechanisms:

A. Rise in pH

  • Mechanism: An increase in the pH of saliva can lead to the precipitation of calcium phosphate salts by lowering the precipitation constant.
  • Causes:
    • Loss of Carbon Dioxide: Bacterial activity in dental plaque can lead to the loss of CO2, resulting in an increase in pH.
    • Formation of Ammonia: The degradation of proteins by plaque bacteria can produce ammonia, further elevating the pH.

B. Colloidal Proteins

  • Mechanism: Colloidal proteins in saliva bind calcium and phosphate ions, maintaining a supersaturated solution with respect to calcium phosphate salts.
  • Process:
    • When saliva stagnates, these colloids can settle out, disrupting the supersaturated state and leading to the precipitation of calcium phosphate salts.

C. Enzymatic Activity

  • Phosphatase:
    • This enzyme, released from dental plaque, desquamated epithelial cells, or bacteria, hydrolyzes organic phosphates in saliva, increasing the concentration of free phosphate ions and promoting mineralization.
  • Esterase:
    • Present in cocci, filamentous organisms, leukocytes, macrophages, and desquamated epithelial cells, esterase can hydrolyze fatty esters into free fatty acids.
    • These fatty acids can form soaps with calcium and magnesium, which are subsequently converted into less-soluble calcium phosphate salts, facilitating calcification.

2. Seeding Agents and Heterogeneous Nucleation

The second theory posits that seeding agents induce small foci of calcification that enlarge and coalesce to form a calcified mass. This concept is often referred to as the epitactic concept or heterogeneous nucleation.

A. Role of Seeding Agents

  • Unknown Agents: The specific seeding agents involved in calculus formation are not fully understood, but it is believed that the intercellular matrix of plaque plays a significant role.
  • Carbohydrate-Protein Complexes:
    • These complexes may initiate calcification by chelating calcium from saliva and binding it to form nuclei that promote the deposition of minerals.

Clinical Implications

  1. Understanding Calculus Formation:

    • Knowledge of the mechanisms behind calculus mineralization can help dental professionals develop effective strategies for preventing and managing calculus formation.
  2. Preventive Measures:

    • Maintaining good oral hygiene practices can help reduce plaque accumulation and the conditions that favor mineralization, such as stagnation of saliva and elevated pH.
  3. Treatment Approaches:

    • Understanding the role of enzymes and proteins in calculus formation may lead to the development of therapeutic agents that inhibit mineralization or promote the dissolution of existing calculus.
  4. Research Directions:

    • Further research into the specific seeding agents and the biochemical processes involved in calculus formation may provide new insights into preventing and treating periodontal disease.

Periodontal Fibers

Periodontal fibers play a crucial role in maintaining the integrity of the periodontal ligament and supporting the teeth within the alveolar bone. Understanding the different groups of periodontal fibers is essential for comprehending their functions in periodontal health and disease.

1. Gingivodental Group

  • Location:
    • Present on the facial, lingual, and interproximal surfaces of the teeth.
  • Attachment:
    • These fibers are embedded in the cementum just beneath the epithelium at the base of the gingival sulcus.
  • Function:
    • They help support the gingiva and maintain the position of the gingival margin.

2. Circular Group

  • Location:
    • These fibers course through the connective tissue of the marginal and interdental gingiva.
  • Attachment:
    • They encircle the tooth in a ring-like fashion.
  • Function:
    • The circular fibers help maintain the contour of the gingiva and provide support to the marginal gingiva.

3. Transseptal Group

  • Location:
    • Located interproximally, these fibers extend between the cementum of adjacent teeth.
  • Attachment:
    • They lie in the area between the epithelium at the base of the gingival sulcus and the crest of the interdental bone.
  • Function:
    • The transseptal fibers are primarily responsible for the post-retention relapse of orthodontically positioned teeth.
    • They are sometimes classified as principal fibers of the periodontal ligament.
    • Collectively, they form the interdental ligament of the arch, providing stability to the interproximal areas.

4. Semicircular Fibers

  • Location:
    • These fibers attach to the proximal surface of a tooth immediately below the cementoenamel junction (CEJ).
  • Attachment:
    • They go around the facial or lingual marginal gingiva of the tooth and attach to the other proximal surface of the same tooth.
  • Function:
    • Semicircular fibers help maintain the position of the tooth and support the gingival tissue around it.

5. Transgingival Fibers

  • Location:
    • These fibers attach to the proximal surface of one tooth and traverse the interdental space diagonally to attach to the proximal surface of the adjacent tooth.
  • Function:
    • Transgingival fibers provide support across the interdental space, helping to maintain the position of adjacent teeth and the integrity of the gingival tissue.

Trauma from Occlusion

Trauma from occlusion refers to the injury sustained by periodontal tissues when occlusal forces exceed their adaptive capacity.

1. Trauma from Occlusion

  • This term describes the injury that occurs to periodontal tissues when the forces exerted during occlusion (the contact between opposing teeth) exceed the ability of those tissues to adapt.
  • Traumatic Occlusion: An occlusion that produces such injury is referred to as a traumatic occlusion. This can result from various factors, including malocclusion, excessive occlusal forces, or parafunctional habits (e.g., bruxism).

2. Clinical Signs of Trauma to the Periodontium

The most common clinical sign of trauma to the periodontium is:

  • Increased Tooth Mobility: As the periodontal tissues are subjected to excessive forces, they may become compromised, leading to increased mobility of the affected teeth. This is often one of the first observable signs of trauma from occlusion.

3. Radiographic Signs of Trauma from Occlusion

Radiographic examination can reveal several signs indicative of trauma from occlusion:

  1. Increased Width of Periodontal Space:

    • The periodontal ligament space may appear wider on radiographs due to the increased forces acting on the tooth, leading to a loss of attachment and bone support.
  2. Vertical Destruction of Inter-Dental Septum:

    • Trauma from occlusion can lead to vertical bone loss in the inter-dental septa, which may be visible on radiographs as a reduction in bone height between adjacent teeth.
  3. Radiolucency and Condensation of the Alveolar Bone:

    • Areas of radiolucency may indicate bone loss, while areas of increased radiopacity (condensation) can suggest reactive changes in the bone due to the stress of occlusal forces.
  4. Root Resorption:

    • In severe cases, trauma from occlusion can lead to root resorption, which may be observed as a loss of root structure on radiographs.

Alveolar Process

The alveolar process is a critical component of the dental anatomy, providing support for the teeth and playing a vital role in periodontal health. Understanding its structure and composition is essential for dental professionals in diagnosing and treating various dental conditions.

Components of the Alveolar Process

  1. External Plate of Cortical Bone:

    • Description: The outer layer of the alveolar process is composed of cortical bone, which is dense and forms a protective outer shell.
    • Composition:
      • Formed by Haversian bone, which consists of organized structures called osteons.
      • Compacted bone lamellae contribute to the strength and stability of the alveolar process.
  2. Alveolar Bone Proper:

    • Description: The inner socket wall of the alveolar process is known as the alveolar bone proper.
    • Radiographic Appearance:
      • It is seen as the lamina dura on radiographs, appearing as a radiopaque line surrounding the tooth roots.
    • Histological Features:
      • Contains a series of openings known as the cribriform plate.
      • These openings allow neurovascular bundles to connect the periodontal ligament with the central component of the alveolar bone, which is the cancellous bone.
  3. Cancellous Bone:

    • Description: Located between the external cortical bone and the alveolar bone proper, cancellous bone consists of trabecular structures.
    • Function:
      • Acts as supporting alveolar bone, providing strength and flexibility to the alveolar process.
    • Interdental Septum:
      • The interdental septum consists of cancellous supporting bone enclosed within a compact border, providing stability between adjacent teeth.

Structural Characteristics

  • Facial and Lingual Portions:
    • Most of the facial and lingual portions of the tooth socket are formed by compact bone alone, providing robust support for the teeth.
  • Cancellous Bone Distribution:
    • Cancellous bone surrounds the lamina dura in specific areas:
      • Apical Areas: The region at the tip of the tooth root.
      • Apicolingual Areas: The area where the root meets the lingual surface.
      • Interradicular Areas: The space between the roots of multi-rooted teeth.

Some important points about the periodontal pocket :
·Soft tissue of pocket wall shows both proliferative & degenerative changes
·Most severe degenerative changes are seen on the lateral wall of pocket
·Plasma cells are the predominant infiltrate (80%). Others include lymphocytes & a scattering of PMNs
·Height of junctional epithelium shortened to only 50-100µm
·Severity of degenerative changes is not linked to pocket depth
·Junctional epithelium starts to lose attachment to tooth when PMN infiltration in junctional epithelium increases above 60%.

Bone Graft Materials

Bone grafting is a critical procedure in periodontal and dental surgery, aimed at restoring lost bone and supporting the regeneration of periodontal tissues. Various materials can be used for bone grafting, each with unique properties and applications.

A. Osseous Coagulum

  • Composition: Osseous coagulum is a mixture of bone dust and blood. It is created using small particles ground from cortical bone.
  • Sources: Bone dust can be obtained from various anatomical sites, including:
    • Lingual ridge of the mandible
    • Exostoses
    • Edentulous ridges
    • Bone distal to terminal teeth
  • Application: This material is used in periodontal surgery to promote healing and regeneration of bone in areas affected by periodontal disease.

B. Bioactive Glass

  • Composition: Bioactive glass consists of sodium and calcium salts, phosphates, and silicon dioxide.
  • Function: It promotes bone regeneration by forming a bond with surrounding bone and stimulating cellular activity.

C. HTR Polymer

  • Composition: HTR Polymer is a non-resorbable, microporous, biocompatible composite made from polymethyl methacrylate (PMMA) and polyhydroxymethacrylate.
  • Application: This material is used in various dental and periodontal applications due to its biocompatibility and structural properties.

D. Other Bone Graft Materials

  • Sclera: Used as a graft material due to its collagen content and biocompatibility.
  • Cartilage: Can be used in certain grafting procedures, particularly in reconstructive surgery.
  • Plaster of Paris: Occasionally used in bone grafting, though less common due to its non-biological nature.
  • Calcium Phosphate Biomaterials: These materials are osteoconductive and promote bone healing.
  • Coral-Derived Materials: Natural coral can be processed to create a scaffold for bone regeneration.

Periodontal Medicaments

Periodontal diseases often require adjunctive therapies to traditional mechanical treatments such as scaling and root planing. Various medicaments have been developed to enhance the healing process and control infection in periodontal tissues. This lecture will discuss several periodontal medicaments, their compositions, and their clinical applications.

1. Elyzol

  • Composition:
    • Elyzol is an oil-based gel containing 25% metronidazole. It is formulated with glyceryl mono-oleate and sesame oil.
  • Clinical Use:
    • Elyzol has been found to be equivalent to scaling and root planing in terms of effectiveness for treating periodontal disease.
    • However, no adjunctive effects beyond those achieved with mechanical debridement have been demonstrated.

2. Actisite

  • Composition:

    • Actisite consists of tetracycline-containing fibers.
    • Each fiber has a diameter of 0.5 mm and contains 12.7 mg of tetracycline per 9 inches of fiber.
  • Clinical Use:

    • The fibers are placed directly into periodontal pockets, where they release tetracycline over time, helping to reduce bacterial load and promote healing.

3. Arestin

  • Composition:

    • Arestin contains minocycline, which is delivered as a biodegradable powder in a syringe.
  • Clinical Use:

    • Arestin is indicated for the treatment of periodontal disease and is applied directly into periodontal pockets, where it provides localized antibiotic therapy.

4. Atridox

  • Composition:

    • Atridox contains 10% doxycycline in a syringeable gel system that is biodegradable.
  • Clinical Use:

    • The gel is injected into periodontal pockets, where it solidifies and releases doxycycline over time, aiding in the management of periodontal disease.

5. Dentamycin and Periocline

  • Composition:

    • Both Dentamycin and Periocline contain 2% minocycline hydrochloride.
  • Clinical Use:

    • These products are used similarly to other local delivery systems, providing localized antibiotic therapy to reduce bacterial infection in periodontal pockets.

6. Periochip

  • Composition:

    • Periochip is a biodegradable chip that contains chlorhexidine.
  • Clinical Use:

    • The chip is placed in the gingival crevice, where it releases chlorhexidine over time, providing antimicrobial action and helping to control periodontal disease.

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