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Periodontics - NEETMDS- courses
NEET MDS Lessons
General Medicine

Type Key Feature
Beta Thalassemia ↓ Beta chains, ↑ Alpha chains
Common mutation Intron-1
Diagnosis Hb electrophoresis
Screening test NESTROFT
Radiology sign Hair-on-end skull appearance
  • Alpha Thalassemia: Caused by deletion of alpha genes
  • HbH Disease: Deletion of 3 alpha chains

Blade Angulation Protocols

Scaling & Root Planing

  • Angulation: 45-90 degrees to tooth surface
  • Purpose: Effective calculus removal and root surface debridement

Gingival Curettage

  • Angulation: >90 degrees
  • Technique: Removal of infected soft tissue from pocket wall

Curette Sharpening

  • Optimal Angle: 100-110 degrees
  • Maintenance: Critical for effective instrumentation

Curette Design

Gracey Curettes

  • Offset Angle: 60 degrees
  • Specificity: Area-specific design for different tooth surfaces

Universal Curettes

  • Angle: 90 degrees
  • Application: Suitable for all tooth surfaces

After-Five Curettes

  • Modification: Terminal shank extended by 3mm
  • Purpose: Access to deep pockets (>5mm)

Probing Systems

CPITN Probe

  • Tip Diameter: 0.5mm
  • Markings: 3.5, 5.5, 8.5, 11.5mm
  • Use: Community periodontal index assessment

Florida Probe

  • Tip Diameter: 0.4mm (more precise)
  • Technology: Computerized probing system

Implant Probing

  • Maximum Force: 25N
  • Probe Type: Plastic probes recommended to prevent implant surface damage

Pathophysiology

  • Enzyme defect: Glucose-6-phosphate dehydrogenase deficiency
  • Result: Impaired NADPH production → reduced glutathione → oxidative damage
  • Inheritance: X-linked recessive (affects males predominantly)

Key Clinical Features

  • Heinz bodies: Characteristic finding (precipitated denatured hemoglobin)
  • Hemolytic episodes: Triggered by oxidative stress
  • Chronic hemolysis: Usually absent between episodes
  • Neonatal jaundice: May be severe

Important Clinical Points

  • Estrogen does NOT induce hemolysis (unlike other conditions)
  • Favism: Hemolysis after eating fava beans
  • Drug-induced: Most common trigger for hemolytic crisis

Oxidative Stressors to Avoid

Medications

  • Antimalarials: Primaquine, chloroquine
  • Antibiotics: Sulfonamides, nitrofurantoin, chloramphenicol
  • Analgesics: Aspirin (high doses), phenazopyridine
  • Others: Methylene blue, naphthalene (mothballs)

Infections

  • Bacterial infections
  • Viral hepatitis
  • Pneumonia
  • Typhoid fever

Other Triggers

  • Fava beans (favism)
  • Diabetic ketoacidosis
  • Severe illness/stress

  • Mineral Sources:
    • Supragingival: Saliva
    • Subgingival: GCF
  • Crystal Composition:
    Crystal Type Percentage
    Hydroxyapatite 58%
    Magnesium whitlockite 21%
    Octacalcium phosphate 12%
    Brushite 8%
  • Color:
    • Supragingival: White/yellow
    • Subgingival: Dark brown/green-black
  • Stains:
    • Green: Chromogenic bacteria
    • Yellow-brown: Chlorhexidine

🗣 Speech & Language

Area Location Damage Effect
Broca’s Dominant inferior frontal gyrus Motor aphasia (impaired expression)
Wernicke’s Dominant superior temporal gyrus Fluent but irrelevant speech

😵‍💫 Headache & Migraine

  • Pain-sensitive meningeal layer: Dura
  • Ophthalmoplegic migraine: III nerve palsy
  • Telcagepant: New anti-migraine drug

🧠 Stroke & Hemorrhage

  • Stroke in young women (India): Cortical vein thrombosis
  • Commonest CVA cause: Embolism
  • ICH most commonly due to: Intracerebral hemorrhage (trauma)
  • Infarction site → hemiplegia: MCA territory
  • Thrombolytic for stroke: Tissue plasminogen activator (tPA)
  • Carotid stenosis management: Aspirin reduces TIA risk

🧠 Cranial Nerves

  • Trigeminal nerve disorder: Tic Douloureux
  • UMN VII palsy: Contralateral lower face paresis
  • Ramsay – Hunt syndrome: Herpes virus
  • Griesinger’s sign: Sigmoid sinus thrombosis

🧠 Parkinsonism

  • Cause: Wilson disease (Copper accumulation)
  • Lazabemide: MAO-B inhibitor

Causes

  • Volatile sulfur compounds: H₂S, methyl mercaptan, dimethyl sulfide

Detection Methods

  • Gold standard: Organoleptic rating (easiest)
  • Most sensitive: Gas chromatography

  • ANUG Staging:
    • Stage 1 – 2: NUG/NUP
    • Stage 3 – 4: NUP
    • Stage 5 – 6: Necrotizing stomatitis
    • Stage 7: Noma
  • Bone Defects:
    • 3-wall: Intrabony
    • 2-wall: Crater
    • 1-wall: Hemiseptum
  • Radiographic Signs: Fuzziness in lamina dura is earliest sign.
  • TFO (Trauma from Occlusion): Widened PDL, thickened lamina dura.
  • Most Susceptible Area: Furcation.

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