Late mandibular growth refers to the continued development and growth of the mandible (lower jaw) that occurs after the typical growth spurts associated with childhood and adolescence. While most of the significant growth of the mandible occurs during these early years, some individuals may experience additional growth in their late teens or early adulthood. Understanding the factors influencing late mandibular growth, its implications, and its relevance in orthodontics and dentistry is essential.

Factors Influencing Late Mandibular Growth

1. Genetics:

   • Genetic factors play a significant role in determining the timing and extent of mandibular growth. Family history can provide insights into an individual's growth patterns.

2. Hormonal Changes:

   • Hormonal fluctuations, particularly during puberty, can influence growth. Growth hormone, sex hormones (estrogen and testosterone), and other endocrine factors can affect the growth of the mandible.

3. Functional Forces:

   • The forces exerted by the muscles of mastication, as well as functional activities such as chewing and speaking, can influence the growth and development of the mandible.

4. Environmental Factors:

   • Nutritional status, overall health, and lifestyle factors can impact growth. Adequate nutrition is essential for optimal skeletal development.

5. Orthodontic Treatment:

   • Orthodontic interventions can influence mandibular growth patterns. For example, the use of functional appliances may encourage forward growth of the mandible in growing patients.

Clinical Implications of Late Mandibular Growth

1. Changes in Occlusion:

   • Late mandibular growth can lead to changes in the occlusal relationship between the upper and lower teeth. This may result in the development of malocclusions or changes in existing malocclusions.

2. Facial Aesthetics:

   • Continued growth of the mandible can affect facial aesthetics, including the profile and overall balance of the face. This may be particularly relevant in individuals with a retrognathic (recessed) mandible or those seeking cosmetic improvements.

3. Orthodontic Treatment Planning:

   • Understanding the potential for late mandibular growth is crucial for orthodontists when planning treatment. It may influence the timing of interventions and the choice of appliances used to guide growth.

4. Surgical Considerations:

   • In some cases, late mandibular growth may necessitate surgical intervention, particularly in adults with significant skeletal discrepancies. Orthognathic surgery may be considered to correct jaw relationships and improve function and aesthetics.

Monitoring Late Mandibular Growth

1. Clinical Evaluation:

   • Regular clinical evaluations, including assessments of occlusion, facial symmetry, and growth patterns, are essential for monitoring late mandibular growth.

2. Radiographic Analysis:

   • Cephalometric radiographs can be used to assess changes in mandibular growth and its relationship to the craniofacial complex. This information can guide treatment decisions.

3. Patient History:

   • Gathering a comprehensive patient history, including growth patterns and any previous orthodontic treatment, can provide valuable insights into late mandibular growth.

Growth is the increase in size It may also be defined as the normal  change in the amount of living substance. eg. Growth is the quantitative aspect and measures in units of increase per unit of time.

Development

It is the progress towards maturity (Todd). Development may be defined as natural sequential series of events between fertilization of ovum and adult stage.

Maturation

It is a period of stabilization brought by growth and development.

CEPHALOCAUDAL GRADIENT OF GROWTH

This simply means that there is an axis of increased growth extending from the head towards feet. At about 3rd month of intrauterine life the head takes up about 50% of total body length. At this stage cranium is larger relative to face. In contrast the limbs are underdeveloped. 

By the time of birth limbs and trunk have grown faster than head and the entire proportion of the body to the head has increased. These processes of growth continue till adult.  

SCAMMON’S CURVE

In normal growth pattern all the tissue system of the body do not growth at the same rate. Scammon’s curve for growth shows 4 major tissue system of the body;

• Neural

• Lymphoid 

• General: Bone, viscera, muscle.

• Genital

The graph indicates the growth of the neural tissue is complete by 6-7 year of age. General body tissue show an “S” shaped curve with showing of rate during childhood and acceleration at puberty. Lymphoid tissues proliferate to its maximum in late childhood and undergo involution. At the same time growth of the genital tissue accelerate rapidly. 

Functional Matrix Hypothesis is a concept in orthodontics and craniofacial biology that explains how the growth and development of the craniofacial complex (including the skull, face, and dental structures) are influenced by functional demands and environmental factors rather than solely by genetic factors. This hypothesis was proposed by Dr. Robert A. K. McNamara and is based on the idea that the functional matrices—such as muscles, soft tissues, and functional activities (like chewing and speaking)—play a crucial role in shaping the skeletal structures.

Concepts of the Functional Matrix Hypothesis

1. Functional Matrices:

   • The hypothesis posits that the growth of the craniofacial skeleton is guided by the functional matrices surrounding it. These matrices include:
     • Muscles: The muscles of mastication, facial expression, and other soft tissues exert forces on the bones, influencing their growth and development.
     • Soft Tissues: The presence and tension of soft tissues, such as the lips, cheeks, and tongue, can affect the position and growth of the underlying skeletal structures.
     • Functional Activities: Activities such as chewing, swallowing, and speaking create functional demands that influence the growth patterns of the craniofacial complex.

2. Growth and Development:

   • According to the Functional Matrix Hypothesis, the growth of the craniofacial skeleton is not a direct result of genetic programming but is instead a response to the functional demands placed on it. This means that changes in function can lead to changes in growth patterns.
   • For example, if a child has a habit of mouth breathing, the lack of proper nasal function can lead to altered growth of the maxilla and mandible, resulting in malocclusion or other dental issues.

3. Orthodontic Implications:

   • The Functional Matrix Hypothesis has significant implications for orthodontic treatment and craniofacial orthopedics. It suggests that:
     • Functional Appliances: Orthodontic appliances that modify function (such as functional appliances) can be used to influence the growth of the jaws and improve occlusion.
     • Early Intervention: Early orthodontic intervention may be beneficial in guiding the growth of the craniofacial complex, especially in children, to prevent or correct malocclusions.
     • Holistic Approach: Treatment should consider not only the teeth and jaws but also the surrounding soft tissues and functional activities.

4. Clinical Applications:

   • The Functional Matrix Hypothesis encourages clinicians to assess the functional aspects of a patient's oral and facial structures when planning treatment. This includes evaluating muscle function, soft tissue relationships, and the impact of habits (such as thumb sucking or mouth breathing) on growth and development.

Forces Required for Tooth Movements

1. Tipping:

   • Force Required: 50-75 grams
   • Description: Tipping involves the movement of a tooth around its center of resistance, resulting in a change in the angulation of the tooth.

2. Bodily Movement:

   • Force Required: 100-150 grams
   • Description: Bodily movement refers to the translation of a tooth in its entirety, moving it in a straight line without tipping.

3. Intrusion:

   • Force Required: 15-25 grams
   • Description: Intrusion is the movement of a tooth into the alveolar bone, effectively reducing its height in the dental arch.

4. Extrusion:

   • Force Required: 50-75 grams
   • Description: Extrusion involves the movement of a tooth out of the alveolar bone, increasing its height in the dental arch.

5. Torquing:

   • Force Required: 50-75 grams
   • Description: Torquing refers to the rotational movement of a tooth around its long axis, affecting the angulation of the tooth in the buccolingual direction.

6. Uprighting:

   • Force Required: 75-125 grams
   • Description: Uprighting is the movement of a tilted tooth back to its proper vertical position.

7. Rotation:

   • Force Required: 50-75 grams
   • Description: Rotation involves the movement of a tooth around its long axis, changing its orientation within the dental arch.

8. Headgear:

   • Force Required: 350-450 grams on each side
   • Duration: Minimum of 12-14 hours per day
   • Description: Headgear is used to control the growth of the maxilla and to correct dental relationships.

9. Face Mask:

   • Force Required: 1 pound (450 grams) per side
   • Duration: 12-14 hours per day
   • Description: A face mask is used to encourage forward growth of the maxilla in cases of Class III malocclusion.

10. Chin Cup:

    • Initial Force Required: 150-300 grams per side
    • Subsequent Force Required: 450-700 grams per side (after two months)
    • Duration: 12-14 hours per day
    • Description: A chin cup is used to control the growth of the mandible and improve facial aesthetics.

Tweed's Analysis

Tweed's analysis is a comprehensive cephalometric method developed by Dr. Charles Tweed in the mid-20th century. It is primarily used in orthodontics to evaluate the relationships between the skeletal and dental structures of the face, particularly focusing on the position of the teeth and the skeletal bases. Tweed's analysis is instrumental in diagnosing malocclusions and planning orthodontic treatment.

Key Features of Tweed's Analysis

1. Reference Planes and Points:

   • Sella (S): The midpoint of the sella turcica, a bony structure in the skull.
   • Nasion (N): The junction of the frontal and nasal bones.
   • A Point (A): The deepest point on the maxillary arch between the anterior nasal spine and the maxillary alveolar process.
   • B Point (B): The deepest point on the mandibular arch between the anterior nasal spine and the mandibular alveolar process.
   • Menton (Me): The lowest point on the symphysis of the mandible.
   • Gnathion (Gn): The midpoint between Menton and Pogonion (the most anterior point on the chin).
   • Pogonion (Pog): The most anterior point on the contour of the chin.
   • Go (Gonion): The midpoint of the contour of the ramus and the body of the mandible.

2. Reference Lines:

   • SN Plane: A line drawn from Sella to Nasion, representing the cranial base.
   • Mandibular Plane (MP): A line connecting Gonion (Go) to Menton (Me), which represents the position of the mandible.
   • Facial Plane (FP): A line drawn from Gonion (Go) to Menton (Me), used to assess the facial profile.

3. Key Measurements:

   • ANB Angle: The angle formed between the lines connecting A Point to Nasion and B Point to Nasion. It indicates the relationship between the maxilla and mandible.
     • Normal Range: Typically between 2° and 4°.
   • SN-MP Angle: The angle between the SN plane and the mandibular plane (MP), which helps assess the vertical position of the mandible.
     • Normal Range: Usually between 32° and 38°.
   • Wits Appraisal: The distance between the perpendiculars dropped from points A and B to the occlusal plane. It provides insight into the anteroposterior relationship of the dental bases.
   • Interincisal Angle: The angle formed between the long axes of the maxillary and mandibular incisors, which helps assess the inclination of the incisors.

4. Tweed's Philosophy:

   • Tweed emphasized the importance of achieving a functional occlusion and a harmonious facial profile. He believed that orthodontic treatment should focus on the relationship between the dental and skeletal structures to achieve optimal results.

Clinical Relevance

• Diagnosis and Treatment Planning: Tweed's analysis helps orthodontists diagnose skeletal discrepancies and plan appropriate treatment strategies. It provides a clear understanding of the patient's craniofacial relationships, which is essential for effective orthodontic intervention.
• Monitoring Treatment Progress: By comparing pre-treatment and post-treatment cephalometric measurements, orthodontists can evaluate the effectiveness of the treatment and make necessary adjustments.
• Predicting Treatment Outcomes: The analysis aids in predicting the outcomes of orthodontic treatment by assessing the initial skeletal and dental relationships.

Anchorage in orthodontics refers to the resistance that the anchorage area offers to unwanted tooth movements during orthodontic treatment. Proper understanding and application of anchorage principles are crucial for achieving desired tooth movements while minimizing undesirable effects on adjacent teeth.

Classification of Anchorage

1. According to Manner of Force Application

• Simple Anchorage:

  • Achieved by engaging a greater number of teeth than those being moved within the same dental arch.
  • The combined root surface area of the anchorage unit must be at least double that of the teeth to be moved.

• Stationary Anchorage:

  • Defined as dental anchorage where the application of force tends to displace the anchorage unit bodily in the direction of the force.
  • Provides greater resistance compared to anchorage that only resists tipping forces.

• Reciprocal Anchorage:

  • Refers to the resistance offered by two malposed units when equal and opposite forces are applied, moving each unit towards a more normal occlusion.
  • Examples:
    • Closure of a midline diastema by moving the two central incisors towards each other.
    • Use of crossbite elastics and dental arch expansions.

2. According to Jaws Involved

• Intra-maxillary Anchorage:
  • All units offering resistance are situated within the same jaw.
• Intermaxillary Anchorage:
  • Resistance units in one jaw are used to effect tooth movement in the opposing jaw.
  • Also known as Baker's anchorage.
  • Examples:
    • Class II elastic traction.
    • Class III elastic traction.

3. According to Site

• Intraoral Anchorage:

  • Both the teeth to be moved and the anchorage areas are located within the oral cavity.
  • Anatomic units include teeth, palate, and lingual alveolar bone of the mandible.

• Extraoral Anchorage:

  • Resistance units are situated outside the oral cavity.
  • Anatomic units include the occiput, back of the neck, cranium, and face.
  • Examples:
    • Headgear.
    • Facemask.

• Muscular Anchorage:

  • Utilizes forces generated by muscles to aid in tooth movement.
  • Example: Lip bumper to distalize molars.

4. According to Number of Anchorage Units

• Single or Primary Anchorage:

  • A single tooth with greater alveolar support is used to move another tooth with lesser support.

• Compound Anchorage:

  • Involves more than one tooth providing resistance to move teeth with lesser support.

• Multiple or Reinforced Anchorage:

  • Utilizes more than one type of resistance unit.
  • Examples:
    • Extraoral forces to augment anchorage.
    • Upper anterior inclined plane.
    • Transpalatal arch.