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Oral and Maxillofacial Surgery

Necrotizing Sialometaplasia

Necrotizing sialometaplasia is an inflammatory lesion that primarily affects the salivary glands, particularly the minor salivary glands. It is characterized by necrosis of the glandular tissue and subsequent metaplastic changes. The exact etiology of this condition remains unknown, but several factors have been suggested to contribute to its development.

Key Features

  1. Etiology:

    • The precise cause of necrotizing sialometaplasia is not fully understood. However, common suggested causes include:
      • Trauma: Physical injury to the salivary glands leading to ischemia (reduced blood flow).
      • Acinar Necrosis: Death of the acinar cells (the cells responsible for saliva production) in the salivary glands.
      • Squamous Metaplasia: Transformation of glandular epithelium into squamous epithelium, which can occur in response to injury or inflammation.
  2. Demographics:

    • The condition is more commonly observed in men, particularly in their 5th to 6th decades of life (ages 50-70).
  3. Common Sites:

    • Necrotizing sialometaplasia typically affects the minor salivary glands, with common locations including:
      • The palate
      • The retromolar area
      • The lip
  4. Clinical Presentation:

    • The lesion usually presents as a large ulcer or an ulcerated nodule that is well-demarcated from the surrounding normal tissue.
    • The edges of the lesion often show signs of an inflammatory reaction, which may include erythema and swelling.
  5. Management:

    • Conservative Treatment: The management of necrotizing sialometaplasia is generally conservative, as the lesion is self-limiting and typically heals on its own.
    • Debridement: Gentle debridement of the necrotic tissue may be performed using hydrogen peroxide or saline to promote healing.
    • Healing Time: The lesion usually heals within 6 to 8 weeks without the need for surgical intervention.

Intraligamentary Injection and Supraperiosteal Technique

Intraligamentary Injection

  • The intraligamentary injection technique is a simple and effective method for achieving localized anesthesia in dental procedures. It requires only a small volume of anesthetic solution and produces rapid onset of anesthesia.
  • Technique:

    1. Needle Placement:
      • The needle is inserted into the gingival sulcus, typically on the mesial surface of the tooth.
      • The needle is then advanced along the root surface until resistance is encountered, indicating that the needle is positioned within the periodontal ligament.
    2. Anesthetic Delivery:
      • Approximately 0.2 ml of anesthetic solution is deposited into the periodontal ligament space.
      • For multirooted teeth, injections should be made both mesially and distally to ensure adequate anesthesia of all roots.
  • Considerations:

    • Significant pressure is required to express the anesthetic solution into the periodontal ligament, which can be a factor to consider during administration.
    • This technique is particularly useful for localized procedures where rapid anesthesia is desired.

Supraperiosteal Technique (Local Infiltration)

  • The supraperiosteal injection technique is commonly used for achieving anesthesia in the maxillary arch, particularly for single-rooted teeth.
  • Technique:

    1. Anesthetic Injection:

      • For the first primary molar, the bone overlying the tooth is thin, allowing for effective anesthesia by injecting the anesthetic solution opposite the apices of the roots.
    2. Challenges with Multirooted Teeth:

      • The thick zygomatic process can complicate the anesthetic delivery for the buccal roots of the second primary molar and first permanent molars.
      • Due to the increased thickness of bone in this area, the supraperiosteal injection at the apices of the roots of the second primary molar may be less effective.
    3. Supplemental Injection:

      • To enhance anesthesia, a supplemental injection should be administered superior to the maxillary tuberosity area to block the posterior superior alveolar nerve.
      • This additional injection compensates for the bone thickness and the presence of the posterior middle superior alveolar nerve plexus, which can affect the efficacy of the initial injection.

Odontogenic Keratocyst (OKC)

The odontogenic keratocyst (OKC) is a unique and aggressive cystic lesion of the jaw with distinct histological features and a high recurrence rate. Below is a comprehensive overview of its characteristics, treatment options, and prognosis.

Characteristics of Odontogenic Keratocyst

  1. Definition and Origin:

    • The term "odontogenic keratocyst" was first introduced by Philipsen in 1956. It is believed to originate from remnants of the dental lamina or basal cells of the oral epithelium.
  2. Biological Behavior:

    • OKCs exhibit aggressive behavior and have a recurrence rate of 13% to 60%. They are considered to have a neoplastic nature rather than a purely developmental origin.
  3. Histological Features:

    • The cyst lining is typically 6 to 10 cells thick, with a palisaded basal cell layer and a surface of corrugated parakeratin.
    • The epithelium may produce orthokeratin (10%), parakeratin (83%), or both (7%).
    • No rete ridges are present, and mitotic activity is frequent, contributing to the cyst's growth pattern.
  4. Types:

    • Orthokeratinized OKC: Less aggressive, lower recurrence rate, often associated with dentigerous cysts.
    • Parakeratinized OKC: More aggressive with a higher recurrence rate.
  5. Clinical Features:

    • Age: Peak incidence occurs in individuals aged 20 to 30 years.
    • Gender: Predilection for males (approximately 1:5 male to female ratio).
    • Location: More commonly found in the mandible, particularly in the ramus and third molar area. In the maxilla, the third molar area is also a common site.
    • Symptoms: Patients may be asymptomatic, but symptoms can include pain, soft-tissue swelling, drainage, and paresthesia of the lip or teeth.
  6. Radiographic Features:

    • Typically appears as a unilocular lesion with a well-defined peripheral rim, although multilocular varieties (20%) can occur.
    • Scalloping of the borders is often present, and it may be associated with the crown of a retained tooth (40%).

Treatment Options for Odontogenic Keratocyst

  1. Surgical Excision:

    • Enucleation: Complete removal of the cyst along with the surrounding tissue.
    • Curettage: Scraping of the cyst lining after enucleation to remove any residual cystic tissue.
  2. Chemical Cauterization:

    • Carnoy’s Solution: Application of Carnoy’s solution (6 ml absolute alcohol, 3 ml chloroform, and 1 ml acetic acid) after enucleation and curettage can help reduce recurrence rates. It penetrates the bone and can assist in freeing the cyst from the bone wall.
  3. Marsupialization:

    • This technique involves creating a window in the cyst to allow for drainage and reduction in size, which can be beneficial in larger cysts or in cases where complete excision is not feasible.
  4. Primary Closure:

    • After enucleation and curettage, the site may be closed primarily or packed open to allow for healing.
  5. Follow-Up:

    • Regular follow-up is essential due to the high recurrence rate. Patients should be monitored for signs of recurrence, especially in the first few years post-treatment.

Prognosis

  • The prognosis for OKC is variable, with a significant recurrence rate attributed to the aggressive nature of the lesion and the potential for residual cystic tissue.
  • Recurrence is not necessarily related to the size of the cyst or the presence of satellite cysts but is influenced by the nature of the lesion itself and the presence of dental lamina remnants.
  • Multilocular lesions tend to have a higher recurrence rate compared to unilocular ones.
  • Surgical technique does not significantly influence the likelihood of relapse.

Associated Conditions

  • Multiple OKCs can be seen in syndromes such as:
    • Nevoid Basal Cell Carcinoma Syndrome (Gorlin-Goltz Syndrome)
    • Marfan Syndrome
    • Ehlers-Danlos Syndrome
    • Noonan Syndrome

Augmentation of the Inferior Border of the Mandible

Mandibular augmentation refers to surgical procedures aimed at increasing the height or contour of the mandible, particularly the inferior border. This type of augmentation is often performed to improve the support for dentures, enhance facial aesthetics, or correct deformities. Below is an overview of the advantages and disadvantages of augmenting the inferior border of the mandible.

Advantages of Inferior Border Augmentation

  1. Preservation of the Vestibule:

    • The procedure does not obliterate the vestibule, allowing for the immediate placement of an interim denture. This is particularly beneficial for patients who require prosthetic support soon after surgery.
  2. No Change in Vertical Dimension:

    • Augmentation of the inferior border does not alter the vertical dimension of the occlusion, which is crucial for maintaining proper bite relationships and avoiding complications associated with changes in jaw alignment.
  3. Facilitation of Secondary Vestibuloplasty:

    • The procedure makes subsequent vestibuloplasty easier. By maintaining the vestibular space, it allows for better access and manipulation during any future surgical interventions aimed at deepening the vestibule.
  4. Protection of the Graft:

    • The graft used for augmentation is not subjected to direct masticatory forces, reducing the risk of graft failure and promoting better healing. This is particularly important in ensuring the longevity and stability of the augmentation.

Disadvantages of Inferior Border Augmentation

  1. Extraoral Scar:

    • The procedure typically involves an incision that can result in an extraoral scar. This may be a cosmetic concern for some patients, especially if the scar is prominent or does not heal well.
  2. Potential Alteration of Facial Appearance:

    • If the submental and submandibular tissues are not initially loose, there is a risk of altering the facial appearance. Tight or inelastic tissues may lead to distortion or asymmetry postoperatively.
  3. Limited Change in Superior Surface Shape:

    • The augmentation primarily affects the inferior border of the mandible and may not significantly change the shape of the superior surface of the mandible. This limitation can affect the overall contour and aesthetics of the jawline.
  4. Surgical Risks:

    • As with any surgical procedure, there are inherent risks, including infection, bleeding, and complications related to anesthesia. Additionally, there may be risks associated with the grafting material used.

Absorbable

Natural

Catgut

Tansor fascia lata

Collagen tape

Synthetic

Polyglycolic acid (Dexon)

Polyglactin (Vicryl)

Polydioxanone (PDS)

Non-absorbable

Natural

Linen

Cotton

Silk

Synthetic

Nylon

Terylene (Dacron)

Polypropylene (Prolene)

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