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Pedodontics

Recurrent Aphthous Ulcers (Canker Sores)

Overview of Recurrent Aphthous Ulcers (RAU)

  • Definition:

    • Recurrent aphthous ulcers, commonly known as canker sores, are painful ulcerations that occur on the unattached mucous membranes of the mouth. They are characterized by their recurrent nature and can significantly impact the quality of life for affected individuals.
  • Demographics:

    • RAU is most prevalent in school-aged children and young adults, with a peak incidence between the ages of 10 and 19 years.
    • It is reported to be the most common mucosal disorder across various ages and races globally.

Clinical Features

  • Characteristics:

    • RAU is defined by recurrent ulcerations on the moist mucous membranes of the mouth.
    • Lesions can be discrete or confluent, forming rapidly in certain areas.
    • They typically feature:
      • A round to oval crateriform base.
      • Raised, reddened margins.
      • Significant pain.
  • Types of Lesions:

    • Minor Aphthous Ulcers:
      • Usually single, smaller lesions that heal without scarring.
    • Major Aphthous Ulcers (RAS):
      • Larger, more painful lesions that may take longer to heal and can leave scars.
      • Also referred to as periadenitis mucosa necrotica recurrens or Sutton disease.
    • Herpetiform Ulcers:
      • Multiple small lesions that can appear in clusters.
  • Duration and Healing:

    • Lesions typically persist for 4 to 12 days and heal uneventfully, with scarring occurring only rarely and usually in cases of unusually large lesions.

Epidemiology

  • Prevalence:
      The condition occurs approximately three times more frequently in white children compared to black children.
    • Prevalence estimates of RAU range from 2% to 50%, with most estimates falling between 5% and 25%. Among medical and dental students, the estimated prevalence is between 50% and 60%.

Associated Conditions

  • Systemic Associations:
    • RAS has been linked to several systemic diseases, including:
      • PFAPA Syndrome: Periodic fever, aphthous stomatitis, pharyngitis, and adenitis.
      • Behçet Disease: A systemic condition characterized by recurrent oral and genital ulcers.
      • Crohn's Disease: An inflammatory bowel disease that can present with oral manifestations.
      • Ulcerative Colitis: Another form of inflammatory bowel disease.
      • Celiac Disease: An autoimmune disorder triggered by gluten.
      • Neutropenia: A condition characterized by low levels of neutrophils, leading to increased susceptibility to infections.
      • Immunodeficiency Syndromes: Conditions that impair the immune system.
      • Reiter Syndrome: A type of reactive arthritis that can present with oral ulcers.
      • Systemic Lupus Erythematosus: An autoimmune disease that can cause various oral lesions.
      • MAGIC Syndrome: Mouth and genital ulcers with inflamed cartilage.

 Anomalies of Number: problems in initiation stage

 Hypodontia: 6% incidence; usually autosomal dominant (50% chance of passing to children) with variable expressivity (e.g., parent has mild while child has severe); most common missing permanent tooth (excluding 3rd molars) is Md 2nd premolar, 2nd most common is X lateral; oligodontia (at least 6 missing), and anodontia

1. Clincial implications: can interfere with function, lack of teeth → ↓ alveolar bone formation, esthetics, hard to replace in young children, implants only after growth completed, severe cases should receive genetic and systemic evaluation to see if other problems

2. Syndromes with hypodontia: Rieger syndrome, incontinentia pigmenti, Kabuki syndrome, Ellis-van Creveld syndrome, epidermolysis bullosa junctionalis, and ectodermal dysplasia (usually X-linked; sparse hair, unable to sweat, dysplastic nails)

Supernumerary teeth: aka hyperdontia; mesiodens when located in palatal midline; occur sporadically or as part of syndrome, common in cleft cases; delayed eruption often a sign that supernumeraries are preventing normal eruption

 

1. Multiple supernumerary teeth: cleidocranial dysplasia/dysostosis, Down’s, Apert, and Crouzon syndromes, etc.

Anomalies of Size: problems in morphodifferentiation stage

Microdontia: most commonly peg laterals; also in Down’s syndrome, hemifacial microsomia

Macrodontia: may be associated with hemifacial hypertrophy

Fusion: more common in primary dentition; union of two developing teeth

Gemination: more common in primary; incomplete division of single tooth bud → bifid crown, one pulp chamber; clinically distinguish from fusion by counting geminated tooth as one and have normal # teeth present (not in fusion)

 Anomalies of Shape: errors during morphodifferentiation stage

Dens evaginatus: extra cusp in central groove/cingulum; fracture can → pulp exposure; most common in Orientals

Dens in dente: invagination of inner enamel epithelium → appearance of tooth within a tooth

Taurodontism: failure of Hertwig’s epithelial root sheath to invaginate to proper level → elongated (deep) pulp chamber, stunted roots; sporadic or associated with syndrome (e.g., amelogenesis imperfecta, Trichodento-osseous syndrome, ectodermal dysplasia)

Conical teeth: often associated with ectodermal dysplasia

Anomalies of Structure: problems during histodifferentiation, apposition, and mineralization stages

Dentinogenesis imperfecta: problem during histodifferentiation where defective dentin matrix → disorganized and atubular circumpulpal dentin; autosomal dominant inheritance; three types, one occurs with osteogenesis imperfecta (brittle bone syndrome); not sensitive despite exposed dentin; primary dentition has bulbous crowns, obliterated pulp chambers, bluish-grey or brownish-yellow teeth that are easily worn; permanent teeth often stained but can be sound

Amelogenesis imperfecta: heritable defect, independent from metabolic, syndromes, or systemic conditions (though similar defects seen with syndromes or environmental insults); four main types (hypoplastic, hypocalcified, hypomaturation, hypoplastic/hypomaturation with taurodontism); proper treatment addresses sensitivity, esthetics, VDO, caries and gingivitis prevention

Enamel hypoplasia: quantitative defect of enamel from problems in apposition stage; localized (caused by trauma) or generalized (caused by infection, metabolic disease, malnutrition, or hereditary disorders) effects; more common in malnourished children; least commonly Md incisors affected, often 1st molars; more susceptible to caries, excessive wearing → lost VDO, esthetic problems, and sensitivity to hot/cold

Enamel hypocalcification: during calcification stage

Fluorosis: excess F ingestion during calcification stage → intrinsic stain, mottled appearance, or brown staining and pitting; mild, moderate, or severe; porous enamel soaks up external stain

Classification of Amelogenesis Imperfecta

Amelogenesis imperfecta (AI) is a group of genetic conditions that affect the development of enamel, leading to various enamel defects. The classification of amelogenesis imperfecta is based on the phenotype of the enamel and the mode of inheritance. Below is a detailed classification of amelogenesis imperfecta.

Type I: Hypoplastic

Hypoplastic amelogenesis imperfecta is characterized by a deficiency in the amount of enamel produced. The enamel may appear thin, pitted, or smooth, depending on the specific subtype.

  1. 1A: Hypoplastic Pitted

    • Inheritance: Autosomal dominant
    • Description: Enamel is pitted and has a rough surface texture.
  2. 1B: Hypoplastic, Local

    • Inheritance: Autosomal dominant
    • Description: Localized areas of hypoplasia affecting specific teeth.
  3. 1C: Hypoplastic, Local

    • Inheritance: Autosomal recessive
    • Description: Similar to 1B but inherited in an autosomal recessive manner.
  4. 1D: Hypoplastic, Smooth

    • Inheritance: Autosomal dominant
    • Description: Enamel appears smooth with a lack of pits.
  5. 1E: Hypoplastic, Smooth

    • Inheritance: Linked dominant
    • Description: Similar to 1D but linked to a dominant gene.
  6. 1F: Hypoplastic, Rough

    • Inheritance: Autosomal dominant
    • Description: Enamel has a rough texture with hypoplastic features.
  7. 1G: Enamel Agenesis

    • Inheritance: Autosomal recessive
    • Description: Complete absence of enamel on affected teeth.

Type II: Hypomaturation

Hypomaturation amelogenesis imperfecta is characterized by enamel that is softer and more prone to wear than normal enamel, often with a mottled appearance.

  1. 2A: Hypomaturation, Pigmented

    • Inheritance: Autosomal recessive
    • Description: Enamel has a pigmented appearance, often with brown or yellow discoloration.
  2. 2B: Hypomaturation

    • Inheritance: X-linked recessive
    • Description: Similar to 2A but inherited through the X chromosome.
  3. 2D: Snow-Capped Teeth

    • Inheritance: Autosomal dominant
    • Description: Characterized by a white, snow-capped appearance on the incisal edges of teeth.

Type III: Hypocalcified

Hypocalcified amelogenesis imperfecta is characterized by enamel that is poorly mineralized, leading to soft, chalky teeth that are prone to rapid wear and caries.

  1. 3A:

    • Inheritance: Autosomal dominant
    • Description: Enamel is poorly calcified, leading to significant structural weakness.
  2. 3B:

    • Inheritance: Autosomal recessive
    • Description: Similar to 3A but inherited in an autosomal recessive manner.

Type IV: Hypomaturation, Hypoplastic with Taurodontism

This type combines features of both hypomaturation and hypoplasia, along with taurodontism, which is characterized by elongated pulp chambers and short roots.

  1. 4A: Hypomaturation-Hypoplastic with Taurodontism

    • Inheritance: Autosomal dominant
    • Description: Enamel is both hypoplastic and hypomature, with associated taurodontism.
  2. 4B: Hypoplastic-Hypomaturation with Taurodontism

    • Inheritance: Autosomal dominant
    • Description: Similar to 4A but with a focus on hypoplastic features.

Apexogenesis

Apexogenesis is a vital pulp therapy procedure aimed at promoting the continued physiological development and formation of the root end of an immature tooth. This procedure is particularly relevant in pediatric dentistry, where the goal is to preserve the vitality of the dental pulp in young patients, allowing for normal root development and maturation of the tooth.

Indications for Apexogenesis

Apexogenesis is typically indicated in cases where the pulp is still vital but has been exposed due to caries, trauma, or other factors. The procedure is designed to maintain the health of the pulp tissue, thereby facilitating the ongoing development of the root structure. It is most commonly performed on immature permanent teeth, where the root has not yet fully formed.

Materials Used

Mineral Trioxide Aggregate (MTA) is frequently used in apexogenesis procedures. MTA is a biocompatible material known for its excellent sealing properties and ability to promote healing. It serves as a barrier to protect the pulp and encourages the formation of a calcified barrier at the root apex, facilitating continued root development.

Signs of Success

The most important indicator of successful apexogenesis is the continuous completion of the root apex. This means that as the pulp remains vital and healthy, the root continues to grow and mature, ultimately achieving the appropriate length and thickness necessary for functional dental health.

Contraindications
While apexogenesis can be a highly effective treatment for preserving the vitality of the pulp in young patients, it is generally contraindicated in children with serious systemic illnesses, such as leukemia or cancer. In these cases, the risks associated with the procedure may outweigh the potential benefits, and alternative treatment options may be considered.

Rubber Dam in Dentistry

The rubber dam is a crucial tool in dentistry, primarily used for isolating teeth during various procedures. Developed by Barnum in 1864, it enhances the efficiency and safety of dental treatments.

Rationale for Using Rubber Dam

  1. Maintains Clean and Visible Field

    • The rubber dam isolates the treatment area from saliva and blood, providing a clear view for the clinician.
  2. Patient Protection

    • Prevents aspiration or swallowing of foreign bodies, such as dental instruments or materials, ensuring patient safety.
  3. Clinician Protection

    • Reduces the risk of exposure to blood and saliva, minimizing the potential for cross-contamination.
  4. Reduces Risk of Cross-Contamination

    • Particularly important in procedures involving the root canal system, where maintaining a sterile environment is critical.
  5. Retracts and Protects Soft Tissues

    • The dam retracts the cheeks, lips, and tongue, protecting soft tissues from injury during dental procedures.
  6. Increases Efficiency

    • Minimizes the need for patient cooperation and frequent rinsing, allowing for a more streamlined workflow.
  7. Application of Medicaments

    • Facilitates the application of medicaments without the fear of dilution from saliva or blood.
  8. Improved Properties of Restorative Material

    • Ensures that restorative materials set properly by keeping the area dry and free from contamination.
  9. Psychological Benefit to the Patient

    • Provides a sense of security and comfort, as patients may feel more at ease knowing that the area is isolated and protected.

Rubber Dam Sheet Specifications

Rubber dam sheets are available in various thicknesses, which can affect their handling and application:

  • Thin: 0.15 mm
  • Medium: 0.20 mm
  • Heavy: 0.25 mm
  • Extra-Heavy: 0.30 mm
  • Special Heavy: 0.35 mm

Sizes and Availability

  • Rubber dam sheets can be purchased in rolls or prefabricated sizes, typically 5” x 5” or 6” x 6”.
  • Non-latex rubber dams are available only in the 6” x 6” size.

Color Options

  • Rubber dams come in various colors. Darker colors provide better visual contrast, while lighter colors can illuminate the operating field and facilitate the placement of radiographic films beneath the dam.

Surface Characteristics

  • Rubber dam sheets have a shiny and a dull surface. The dull surface is typically placed facing occlusally, as it is less reflective and reduces glare, enhancing visibility for the clinician.

Herpetic Gingivostomatitis

Herpetic gingivostomatitis is an infection of the oral cavity caused by the herpes simplex virus (HSV), primarily HSV type 1. It is characterized by inflammation of the gingiva and oral mucosa, and it is most commonly seen in children.

Etiology and Transmission

  • Causative Agent: Herpes simplex virus (HSV).
  • Transmission: The virus is communicated through personal contact, particularly via saliva. Common routes include:
    • Direct contact with an infected individual.
    • Transmission from mother to child, especially during the neonatal period.

Epidemiology

  • Prevalence: Studies indicate that antibodies to HSV are present in 40-90% of individuals across different populations, suggesting widespread exposure to the virus.
  • Age of Onset:
    • The incidence of primary herpes simplex infection increases after 6 months of age, peaking between 2 to 5 years.
    • Infants under 6 months are typically protected by maternal antibodies.

Clinical Presentation

  • Incubation Period: 3 to 5 days following exposure to the virus.
  • Symptoms:
    • General Symptoms: Fever, headache, malaise, and oral pain.
    • Oral Symptoms:
      • Initial presentation includes acute herpetic gingivostomatitis, with the gingiva appearing red, edematous, and inflamed.
      • After 1-2 days, small vesicles develop on the oral mucosa, which subsequently rupture, leading to painful ulcers with diameters of 1-3 mm.

Course of the Disease

  • Self-Limiting Nature: The primary herpes simplex infection is usually self-limiting, with recovery typically occurring within 10 days.
  • Complications: In severe cases, complications may arise, necessitating hospitalization or antiviral treatment.

Treatment

  • Supportive Care:
    • Pain management with analgesics for fever and discomfort.
    • Ensuring adequate hydration through fluid intake.
    • Topical anesthetic ointments may be used to facilitate eating and reduce pain.
  • Severe Cases:
    • Hospitalization may be required for severe symptoms or complications.
    • Antiviral agents (e.g., acyclovir) may be administered in severe cases or for immunocompromised patients.

Recurrence of Herpetic Infections

  • Reactivation: Recurrent herpes simplex infections are due to the reactivation of HSV, which remains dormant in nerve tissue after the primary infection.
  • Triggers for Reactivation:
    • Mucosal injuries (e.g., from dental treatment).
    • Environmental factors (e.g., sunlight exposure, citrus fruits).
  • Location of Recurrence: Recurrent infections typically occur at the same site as the initial infection, commonly manifesting as herpes labialis (cold sores).

Distraction Techniques in Pediatric Dentistry

Distraction is a valuable technique used in pediatric dentistry to help manage children's anxiety and discomfort during dental procedures. By diverting the child's attention away from the procedure, dental professionals can create a more positive experience and reduce the perception of pain or discomfort.

Purpose of Distraction

  • Divert Attention: The primary goal of distraction is to shift the child's focus away from the dental procedure, which may be perceived as unpleasant or frightening.
  • Reduce Anxiety: Distraction can help alleviate anxiety and fear associated with dental visits, making it easier for children to cooperate during treatment.
  • Enhance Comfort: Providing a break or a moment of distraction during stressful procedures can enhance the overall comfort of the child.

Techniques for Distraction

  1. Storytelling:

    • Engaging the child in a story can capture their attention and transport them mentally away from the dental environment.
    • Stories can be tailored to the child's interests, making them more effective.
  2. Counting Teeth:

    • Counting the number of teeth loudly can serve as a fun and interactive way to keep the child engaged.
    • This technique can also help familiarize the child with the dental procedure.
  3. Repetitive Statements of Encouragement:

    • Providing continuous verbal encouragement can help reassure the child and keep them focused on positive outcomes.
    • Phrases like "You're doing great!" or "Just a little longer!" can be effective.
  4. Favorite Jokes or Movies:

    • Asking the child to recall a favorite joke or movie can create a light-hearted atmosphere and distract them from the procedure.
    • This technique can also foster a sense of connection between the dentist and the child.
  5. Audio-Visual Aids:

    • Utilizing videos, cartoons, or music can provide a visual and auditory distraction that captures the child's attention.
    • Headphones with calming music or engaging videos can be particularly effective during procedures like local anesthetic administration.

Application in Dental Procedures

  • Local Anesthetic Administration: Distraction techniques can be especially useful during the administration of local anesthetics, which may cause discomfort. Engaging the child in conversation or using visual aids can help minimize their focus on the injection.

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