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282+ quick-fire dental facts • tap a card to flip

Showing page 1 of 32 (282 total shorts) — subject: "Pathology"
#1 Pathology
HbA prevents sickling in sickle cell trait patients because the presence of normal hemoglobin (HbA) reduces the proportion of HbS, preventing polymerization.
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Answer
Sickle cell trait patient do not have manifestations as that of Sickle cell disease, because-
1) 50% HbS is required for occurrence of sickling
2) HbA prevents sickling
3) 50% sickles
4) HbA prevents polymerization of Hbs
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#2 Pathology
The defect leading to thalassemia lies in the hemoglobin itself, specifically in the globin chain synthesis.
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Answer
Defect leading to thalassemia lies in -
1) Haemoglobin
2) Osmotic fragility
3) RBC membrane
4) Platelets
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#3 Pathology
Bullae in a localized cutaneous infection with Staphylococcus aureus typically develop high in the epidermis due to the infection.
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At what level in the skin do bullae MOST likely develop in a localized cutaneous infection around the mouth with phage group II Staphylococcus aureus?

1) Across the basal cells
2) Below the basement membrane
3) Between the basal cells and the basement membrane
4) High in the epidermis

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#4 Pathology
Barrett's esophagus is the primary lesion associated with an increased risk of adenocarcinoma of the distal esophagus.
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Answer

What is the primary lesion associated with an increased risk of adenocarcinoma of the distal esophagus?
1) Generalized fatigue
2) Goodpasture's syndrome
3) Barrett's esophagus
4) Sarcoma

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#5 Pathology
Birbeck’s granules are characteristic of Langerhans cells, which are involved in the immune response and are found in the skin.
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Answer
Birbeck’s granules in the cytoplasm are seen in:
1) Langerhans cells
2) Mast cells
3) Myelocytes
4) Thrombocytes
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#6 Pathology

Correct answer: B) In an Aa × Aa cross, offspring genotypes are 1 AA : 2 Aa : 1 aa. Since homozygous dominant (AA) is typically incompatible with life in true autosomal dominant disorders, and Aa individuals are affected, only the aa (25%) offspring are unaffected.

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Answer

If both parents are heterozygous carriers of an autosomal dominant disorder allele (Aa × Aa), what proportion of offspring is expected to be completely unaffected?
1) 0%
2) 25%
3) 50%
4) 75%

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#7 Pathology
Hypertension is not a typical feature of Paget disease of bone; it is characterized by a mosaic pattern of newly formed woven bone.
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Answer

Which of the following is NOT a typical feature of Paget disease of bone?
1) Mosaic pattern of newly formed woven bone
2) Increased hat size
3) Hypertension
4) Osteosclerotic bones in late stages

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#8 Pathology
Epitheloid cells are a hallmark of granulomatous inflammation, which occurs in response to certain chronic infections (like tuberculosis), autoimmune diseases, and foreign body reactions. In granulomas, epitheloid cells aggregate to form a protective wall around the irritant.
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Answer

Epitheloid cells are characteristic of:
1. Chronic Infection
2. Granulation tissue
3. Granulomatous Inflammation
4. Only In tuberculosis

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#9 Pathology

Correct answer: B) NK cell inhibitory receptors (like KIR) are normally engaged by class I MHC on healthy cells, suppressing NK activity. When tumor cells or virus-infected cells downregulate class I MHC ("missing self"), inhibition is lost and activation signals dominate, triggering NK-mediated killing.

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Answer

Natural killer (NK) cells are triggered to kill target cells primarily when the target shows:
1) Increased class I MHC expression
2) Decreased or absent class I MHC expression
3) Increased class II MHC expression
4) Normal class I MHC density

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