What is the major effector of cell injury in alcoholic hepatitis?
1) Tumor Necrosis Factor (TNF)
2) Interferon gamma (IFN-?)
3) Interleukin-10 (IL-10)
4) Interleukin-4 (IL-4)
📝 Explanation:
TNF is considered the main effector of injury in alcoholic hepatitis. It is produced by activated macrophages, particularly Kupffer cells, and plays a critical role in the initiation and perpetuation of inflammation and necrosis in the liver.