NEET MDS Quiz - Practice Test

1

General Medicine

What is the primary function of the glomerular basement membrane (GBM) in the nephrotic syndrome?
1) Preventing the passage of red blood cells
2) Regulating ion transport
3) Preventing the passage of proteins
4) Maintaining the structure of the renal corpuscle

Option 1

Option 2

Option 3

Option 4

📝 Explanation:

The GBM is a critical component of the glomerular filtration barrier that normally prevents the passage of proteins into the urine. In the nephrotic syndrome, there are alterations in the GBM that lead to increased permeability and loss of proteins, particularly albumin, into the glomerular filtrate.

2

General Medicine

What is the role of antithrombin III in the coagulation process?
1) Activates thrombin
2) Inhibits thrombin
3) Stabilizes fibrin clots
4) Activates factor X

Option 1

Option 2

Option 3

Option 4

📝 Explanation:

Antithrombin III is a serine protease inhibitor that plays a critical role in regulating blood coagulation by inhibiting thrombin (factor IIa) and other serine proteases in the coagulation cascade. This helps maintain the delicate balance between clot formation and dissolution.

3

General Medicine

What is the most common neurological manifestation of Wilson�s disease?
1) Movement disorders
2) Cognitive impairment
3) Seizures
4) Peripheral neuropathy

Option 1

Option 2

Option 3

Option 4

📝 Explanation:

Movement disorders, particularly those associated with basal ganglia dysfunction such as dystonia and chorea, are the most common neurological manifestations of Wilson�s disease due to the primary toxic effect on the basal ganglia from copper deposition.

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