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Pathology - 3 Questions
1. Noduloulcerative Basal Cell Carcinoma: This is the most common subtype of BCC, making up about 60-70% of all cases. It typically appears as a slowly growing, round to oval, pearly or translucent nodule with a central ulceration that may bleed or ooze. The borders of the lesion are often not well-defined and may have a rolled, pearly edge with telangiectasias (small, dilated blood vessels). 2. Cystic Basal Cell Carcinoma: This subtype presents as a round, dome-shaped lesion with a cystic or fluid-filled center. It is less common than the noduloulcerative type, and it may be mistaken for a benign cyst or epidermoid cyst. 3. Morphoeic Basal Cell Carcinoma: Also known as sclerosing or morpheaform BCC, this type is characterized by a slowly growing, ill-defined, firm, plaque-like lesion that can infiltrate deeply into the skin. It may have a whitish, waxy appearance with a scar-like texture. Morphoeic BCC tends to be more aggressive and can be challenging to diagnose due to its subtlety. 4. Pigmented Basal Cell Carcinoma: This is a less common variant of BCC, accounting for approximately 6-15% of cases. It presents with pigmentation in the lesion, which can be brown, blue, or black. The presence of pigment can make it look similar to melanoma, another type of skin cancer, so a biopsy is often necessary to confirm the diagnosis.
Slightly raised vesicles rupturing to form ulcers are a feature of 1) Rubeola 2) Rubella 3) Condyloma acuminatum 4) Chicken pox
Chicken pox presents with multiple dermal lesions characteristically with vesicles, pustules which may secondarily ulcerate
All of the listed conditions (leukoplakia, solar keratosis, and margins of long-standing draining sinuses) are known precursors to squamous cell carcinoma.
MCQ