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NEET MDS Quiz - Practice Test
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Practice Test

General Surgery - 3 Questions

1
General Surgery
Most virus associated malignancy is 

1. Carcinoma cervix 
2. Burkitt's lymphoma 
3. Carcinoma Breast
4. All of above

πŸ“ Explanation:

Carcinoma cervix is strongly associated with Human Papillomavirus (HPV) infection, particularly high-risk strains such as HPV-16 and HPV-18.

Persistent infection with these oncogenic HPV types leads to integration of viral DNA into host cells, producing viral oncoproteins E6 and E7, which inactivate tumor suppressor genes p53 and Rb respectively. This promotes uncontrolled cell proliferation and malignant transformation.

Burkitt’s lymphoma is associated with Epstein-Barr Virus (EBV), but its incidence is geographically limited (endemic in equatorial Africa).

Carcinoma breast has no established viral association; it is linked more to genetic, hormonal, and lifestyle factors.

2
General Surgery
Which of the following salivary gland tumors shows perineural spread
1. Warthin's tumor
2. Adenoid cystic carcinoma
3. Carcinoma in pleomorphic adenoma
4. Mucoepidermoid carcinoma

πŸ“ Explanation:

Adenoid cystic carcinoma (AdCC) is a malignant tumor known for its characteristic slow growth but high propensity for perineural invasion (spread along nerves).

Perineural spread involves the tumor cells migrating along nerve sheaths and is a significant factor in the tumor's aggressive behavior and potential for recurrence. 

Warthin's tumor is a benign tumor and does not show perineural spread.

Carcinoma in pleomorphic adenoma is a malignant tumor but perineural spread is not its defining feature.

Mucoepidermoid carcinoma is also a malignant tumor, but perineural spread is less common compared to adenoid cystic carcinoma.

3
General Surgery
A T2 tumor of the oral cavity near the mandible is best treated with
1.Radiotherapy
2.Chemotherapy
3.Surgery
4.Laser ablation

πŸ“ Explanation:

For a T2 tumor (a tumor larger than 2 cm but not larger than 4 cm) of the oral cavity, surgery is generally considered the primary and best treatment option.

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