All of the following statements about the typical feature of a periapical
granuloma are true EXCEPT
1) It consists of proliferating granulation tissue
2) It can form only if the periapical bone is resorbed
3) It shows evidence of local antibody production
4) It results from immunologically mediated tissue damage
📝 Explanation:
Periapical granulomas were diagnosed as well-circumscribed periapical
radiolucency measuring less than 1.5 cm in diameter, periapical cysts were
characterized by well-defined periapical radiolucency with sclerotic borders
measuring greater than 1.5 cm, and periapical abscesses were characterized by
ill-defined periapical radiolucency with diffuse margins.
While bone resorption can occur in the presence of a periapical granuloma, it
is not a prerequisite for its formation. A periapical granuloma can develop in
response to pulp necrosis or infection without necessarily requiring bone
resorption to occur first. The granuloma can form as a reaction to the
inflammatory process, regardless of the state of the surrounding bone.