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NEET MDS Quiz - Practice Test
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Oral Medicine - 3 Questions

1
Oral Medicine

What is the primary target of antifungal agents such as nystatin and clotrimazole in treating oral candidiasis?
(1) Sterols in the fungal cell membrane
(2) Lipids in the fungal cell membrane
(3) Proteins in the fungal cell membrane
(4) Carbohydrates in the fungal cell membrane

📝 Explanation:

Nystatin and clotrimazole target ergosterol in the fungal cell membrane, leading to increased permeability and death of the fungal cells. This mechanism is specific to fungal cells and does not harm human cells, which lack ergosterol in their membranes.

2
Oral Medicine

What is the primary mode of diagnosis for Huntington's disease?
1) Brain MRI
2) Genetic testing
3) Clinical examination and family history
4) Cerebral spinal fluid analysis

📝 Explanation:

The primary mode of diagnosis for Huntington's disease is genetic testing. It involves identifying the expansion of a trinucleotide repeat (CAG) in the HTT gene on chromosome 4.

3
Oral Medicine

In a patient with nephrotic syndrome, which of the following is true regarding plasma cholesterol levels?
(1) Plasma cholesterol levels are decreased due to increased LDL receptors in the liver.
(2) Plasma cholesterol levels are increased due to the loss of cholesterol in urine.
(3) Plasma cholesterol levels are normal as the condition is unrelated to lipid metabolism.
(4) Plasma cholesterol levels are decreased due to increased hepatic synthesis of bile salts.

📝 Explanation:

Nephrotic syndrome is associated with hyperlipidemia, particularly increased levels of LDL and cholesterol. The underlying mechanism involves the loss of albumin in the urine, which leads to hypoalbuminemia. This causes an increased synthesis of very low-density lipoproteins (VLDL) by the liver to compensate for the loss of oncotic pressure. Additionally, the loss of proteins that normally bind to cholesterol in the blood, such as lipoproteins, results in decreased clearance of LDL.

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