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pharmacology - 3 Questions
Which of the following Antimicrobials has Antipseudomonal action:
1) Cefopodoxime proxetil 2) Ceforanide 3) Cefotetan 4) Cefoperazone
Cephalosporins with antipseudomonal action: Cefoperazone Ceftazidime
Which one of the following drugs increases gastrointestinal motility? 1) Glycopyrrolate. 2) Atropine. 3) Neostigmine. 4) Fentanyl.
Synthetic opioids, sharing properties of opium and morphine, include meperidine, propoxyphene, diphenoxylate, fentanyl, buprenorphine, methadone, and pentazocine. Various opiate effects are analgesia, respiratory depression, constipation, and euphoria. Fentanyl (80 to 100 times more powerful than morphine) is especially dangerous. Atropine blocks the muscarinic receptors. Atropine decreases gastrointestinal tract motility and secretion and causes constipation. Although various derivatives and congeners of atropine (such as propantheline, isopropamide, and glycopyrrolate) have been advocated in patients with peptic ulcer or with diarrheal syndromes Neostigmine is Cholinesterase inhibitors that enhance the effects of parasympathetic stimulation and leads to reversal of intoxication by agents with a anticholinergic action
In Dicumarol poisoning which Vit K is used
1) Menadione 2) Menaqunone 3) Phytonadione 4) None of the above
To reverse the effect of overdose of oral anticoagulants: Phytonadione (K1) is the preparation of choice, because it acts most rapidly, dose depends on the severity of upoprothrombinemia & bleeding.