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NEET MDS Quiz - Practice Test
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medicine - 3 Questions

1
Medicine
The treatment of choice in pauci immune crescentic glomerulonephritis is
1. Methylprednisolone + cyclophosphamide
2. Oral prednisolone
3. Immunoglobulin
4. Cyclophosphamide

📝 Explanation:

Pauci-immune crescentic glomerulonephritis (GN) is typically associated with ANCA-associated vasculitis. The standard treatment for this condition involves a combination of high-dose corticosteroids (such as methylprednisolone) and an immunosuppressive agent, most commonly cyclophosphamide, to induce remission. This combined approach is more effective than monotherapy with either agent alone.

2
Medicine
Following is increased on estrogen therapy
1. Triglyceride
2. Cholesterol
3. VLDL
4. LDL

📝 Explanation:

1. Triglyceride Increased Estrogen therapy stimulates hepatic VLDL production, which leads to an increase in plasma triglycerides. This is a well-known metabolic effect.

2. Cholesterol Not consistently increased Estrogen tends to decrease total cholesterol and LDL, while increasing HDL. So this option is not correct.

3. VLDL Increased (secondary to triglycerides) Estrogen increases hepatic secretion of VLDL, but the most clinically emphasized effect is the rise in triglycerides (since VLDL is the carrier of triglycerides).

4. LDL Decreased Estrogen therapy lowers LDL cholesterol, which is considered a beneficial effect.

3
Medicine
A patient was taken up for measurement of the electromechanical systole, QS2, left ventricular ejection time (LVET) and pre-ejection period. While doing the test, it is noted that the carotid transducer measuring pressure is not functioning. Which of the following cannot be measured?
1. QS2
2. LVET and PEP
3. QS2 and LVET
4. QS2 and PEP

📝 Explanation:

QS2 (electromechanical systole): Interval from the onset of the Q wave on ECG to the second heart sound (aortic valve closure).

Can be measured using ECG + phonocardiogram (no carotid pulse needed).

LVET (Left Ventricular Ejection Time): Duration of blood ejection from LV, measured from the upstroke to the dicrotic notch of the carotid pulse tracing.Requires carotid pulse recording.

PEP (Pre-ejection period): Interval from onset of ventricular depolarization (Q wave) to the beginning of LV ejection (upstroke of carotid pulse). Also requires carotid pulse recording.


If the carotid transducer is not functioning, you cannot measure:

LVET (needs carotid upstroke → dicrotic notch)

PEP (needs carotid upstroke relative to Q wave)

But you can still measure QS2 using ECG + phonocardiogram.

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